Lrp5 Gene Search Result

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2 records found for search term Lrp5

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1319617	LRP5	LDL receptor related protein 5	This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on th ... (more) e basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]	11	68298412	68449275	Human	1309	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
1606195	LRP5L	LDL receptor related protein 5 like (pseudogene)	INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2-methylcholine	22	25351418	25405408	Human	19	symbol , COSMIC , Human Proteome Map	gene, pseudo, MODEL [RefSeq]