Hgs Gene Search Result

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7 records found for search term Hgs

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
733649	HGS	hepatocyte growth factor-regulated tyrosine kinase substrate	The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation. [pro ... (more) vided by RefSeq, Dec 2010]	17	81684011	81702121	Human	166	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
16563504	AC139530.1	novel transcript, antisense to HGS					Human		name	gene, lncrna
16567709	AC139530.3	novel transcript, antisense to HGS					Human		name	gene, lncrna
1606456	HGSNAT	heparan-alpha-glucosaminide N-acetyltransferase	This gene encodes a lysosomal acetyltransferase, which is one of several enzymes involved in the lysosomal degradation of heparin sulfate. Mutations in this gene are associated with Sanfilippo syndrome C, one type of the lysosomal storage disease mucopolysaccaridosis III, which results from impaired ... (more) degradation of heparan sulfate. [provided by RefSeq, Jan 2009]	8	43140464	43202855	Human	484	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
1606879	GSTK1	glutathione S-transferase kappa 1	This gene encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification. The encoded protein is localized to the peroxisome and catalyzes the conjugation of glutathione to a wide range of hydrophobic substates facilitating the remo ... (more) val of these compounds from cells. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009]	7	143263441	143269115	Human	236	old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]
1349768	GSTM3	glutathione S-transferase mu 3	Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encod ... (more) es a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008]	1	109733937	109741038	Human	446	old_gene_name	gene, protein-coding, REVIEWED [RefSeq]
1601696	FAM174A	family with sequence similarity 174 member A	Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]	5	100535374	100586741	Human	58	old_gene_name	gene, protein-coding, VALIDATED [RefSeq]