Folr1 Gene Search Result

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5 records found for search term Folr1

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1346305	FOLR1	folate receptor alpha	The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidyl ... (more) inositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2009]	11	72189709	72196323	Human	269	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
616336042	FOLR1-AS1	FOLR1 antisense RNA 1		11	72163322	72209241	Human		symbol , COSMIC , name , Human Proteome Map	gene, ncrna, VALIDATED [RefSeq]
1318329	FOLR2	folate receptor beta	The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolat ... (more) e to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]	11	72216794	72221950	Human	118	description , old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]
16561064	AP000812.3	folate receptor 1 (adult) (FOLR1) pseudogene					Human		name	gene, unprocessed_pseudogene
1349897	FOLR1P1	folate receptor 1 pseudogene 1		11	72158833	72159656	Human		symbol , GTEx , COSMIC , Human Proteome Map , old_gene_symbol	gene, pseudo, INFERRED [RefSeq]