| 736452 | FMO1 | flavin containing dimethylaniline monoxygenase 1 | Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Thre e forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013] | 1 | 171248494 | 171285978 | Human | 297 | symbol , COSMIC , description , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 38674514 | FMO1-AS1 | FMO1 antisense RNA 1 | | 1 | 171120372 | 171251889 | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, ncrna, MODEL [RefSeq] |
| 16555031 | BX284613.2 | novel transcript, antisense to FMO1 | | | | | Human | | name | gene, lncrna |
| 2303691 | FMO10P | flavin containing dimethylaniline monoxygenase 10, pseudogene | | 1 | 166649150 | 166699360 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 2881129 | FMO11P | flavin containing dimethylaniline monoxygenase 11, pseudogene | | 1 | 166767570 | 166792767 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 733627 | FMO2 | flavin containing dimethylaniline monoxygenase 2 | This gene encodes a flavin-containing monooxygenase family member. It is an NADPH-dependent enzyme that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, some human populations contain an allele (FMO2*2A) with a premature stop codon, resulting in a protein that is C-terminally-truncated, has no catalytic activity, and is likely degraded rapidly. This gene is found in a cluster with other related family members on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014] | 1 | 171185300 | 171212686 | Human | 191 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 733168 | FMO5 | flavin containing dimethylaniline monoxygenase 5 | Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Thre e forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009] | 1 | 147184305 | 147227284 | Human | 196 | description | gene, protein-coding, REVIEWED [RefSeq] |