| 69022 | FDPS | farnesyl diphosphate synthase | This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for p rotein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2008] | 1 | 155308866 | 155320665 | Human | 398 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1606652 | FDPSP1 | farnesyl diphosphate synthase pseudogene 1 | | 1 | 187563027 | 187564175 | Human | | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, pseudo, INFERRED [RefSeq] |
| 1602263 | FDPSP2 | farnesyl diphosphate synthase pseudogene 2 | INTERACTS WITH 3-isobutyl-1-methyl-7H-xanthine; benzo[a]pyrene; bisphenol F | 7 | 76470020 | 76475000 | Human | 6 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, pseudo, PROVISIONAL [RefSeq] |
| 1350506 | FDPSP3 | farnesyl diphosphate synthase pseudogene 3 | | 14 | 54884807 | 54886244 | Human | | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, pseudo, INFERRED [RefSeq] |
| 1347692 | FDPSP4 | farnesyl diphosphate synthase pseudogene 4 | | 15 | 42939253 | 42940404 | Human | | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, pseudo, INFERRED [RefSeq] |
| 1345163 | FDPSP5 | farnesyl diphosphate synthase pseudogene 5 | | X | 44475971 | 44477480 | Human | | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, pseudo, INFERRED [RefSeq] |
| 1353374 | FDPSP6 | farnesyl diphosphate synthase pseudogene 6 | | 21 | 20388287 | 20388845 | Human | | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, pseudo, INFERRED [RefSeq] |
| 2303432 | FDPSP7 | farnesyl diphosphate synthase pseudogene 7 | | 7 | 76968136 | 76969310 | Human | | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, pseudo, INFERRED [RefSeq] |
| 4144937 | FDPSP8 | farnesyl diphosphate synthase pseudogene 8 | INTERACTS WITH aristolochic acid A | 1 | 211660133 | 211661299 | Human | 1 | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 4144923 | FDPSP9 | farnesyl diphosphate synthase pseudogene 9 | | 15 | 79944444 | 79945632 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 4145239 | FDPSP10 | farnesyl diphosphate synthase pseudogene 10 | | 15 | 43140094 | 43141267 | Human | | symbol , GTEx , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |