| 1343864 | EIF2S2 | eukaryotic translation initiation factor 2 subunit beta | Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene rep resenting the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015] | 20 | 34088309 | 34112243 | Human | 187 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 16565816 | AC010738.1 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa (EIF2S2) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16561851 | AL161670.2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa (EIF2S2) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16560243 | AP001646.1 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa (EIF2S2) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16552276 | AL021407.1 | pseudogene similar to part of eukaryotic translation initiation factor 2 subunit 2 EIF2S2 | | | | | Human | | name | gene, processed_pseudogene |
| 1349546 | EIF2S2P1 | eukaryotic translation initiation factor 2 subunit 2 beta pseudogene 1 | | 14 | 63734675 | 63736219 | Human | | symbol , GTEx , COSMIC , Human Proteome Map , old_gene_symbol | gene, pseudo, INFERRED [RefSeq] |
| 1343874 | EIF2S2P2 | eukaryotic translation initiation factor 2 subunit 2 beta pseudogene 2 | INTERACTS WITH benzo[a]pyrene | 3 | 185245166 | 185246567 | Human | 1 | symbol , COSMIC , Human Proteome Map | gene, pseudo, VALIDATED [RefSeq] |
| 1352428 | EIF2S2P3 | eukaryotic translation initiation factor 2 subunit 2 beta pseudogene 3 | | 10 | 92668451 | 92669847 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 2800935 | EIF2S2P4 | eukaryotic translation initiation factor 2 subunit 2 beta pseudogene 4 | INTERACTS WITH aristolochic acid A; cadmium dichloride; lead diacetate | 2 | 170751691 | 170753082 | Human | 3 | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 4108858 | EIF2S2P5 | eukaryotic translation initiation factor 2 subunit 2 beta pseudogene 5 | | 1 | 114468205 | 114469566 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 3231911 | EIF2S2P6 | eukaryotic translation initiation factor 2 subunit 2 beta pseudogene 6 | | 11 | 82835412 | 82837442 | Human | | symbol , GTEx , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 2881249 | EIF2S2P7 | eukaryotic translation initiation factor 2 subunit 2 beta pseudogene 7 | | 2 | 57048152 | 57049465 | Human | | symbol , GTEx , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 735608 | EIF2S1 | eukaryotic translation initiation factor 2 subunit alpha | The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36- kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010] | 14 | 67360328 | 67386516 | Human | 641 | description | gene, protein-coding, VALIDATED [RefSeq] |