| 1312854 | DNTT | DNA nucleotidylexotransferase | This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malig nant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008] | 10 | 96304434 | 96338564 | Human | 77 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 16554418 | AL136181.1 | novel transcript, antisense to DNTT | | | | | Human | | name | gene, lncrna |
| 1322651 | DNTTIP1 | deoxynucleotidyltransferase terminal interacting protein 1 | DNTTIP1 binds DNA and enhances the activity of terminal deoxynucleotidyltransferase (TDT, or DNTT; MIM 187410), a DNA polymerase that catalyzes the polymerization of DNA in the absence of a DNA template (Yamashita et al., 20 01 [PubMed 11473582]).[supplied by OMIM, Mar 2008] | 20 | 45791954 | 45811418 | Human | 71 | symbol , COSMIC , description , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1604625 | DNTTIP2 | deoxynucleotidyltransferase terminal interacting protein 2 | This gene is thought to be involved in chromatin remodeling and gene transcription. The encoded nuclear protein binds to and enhances the transcriptional activity of the estrogen receptor alpha, and also interacts with terminal deoxynucleotidyltransferase. The expression profile of this gene is a po tential biomarker for chronic obstructive pulmonary disease. [provided by RefSeq, Dec 2010] | 1 | 93866284 | 93879206 | Human | 94 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |