| 1316904 | DMC1 | DNA meiotic recombinase 1 | This gene encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins). Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis. This protein, which is evolutionarily conserved, is reported to be essential for meiotic homologous recombination and may thus play an important role in generating diversity of genetic information. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013] | 22 | 38509147 | 38570183 | Human | 133 | symbol , old_gene_name , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1322878 | HID1 | HID1 domain containing | Predicted to act upstream of or within several processes, including insulin processing; secretory granule maturation; and vacuole fusion, non-autophagic. Located in Golgi apparatus; cytoplasmic microtubule; and cytosol. Implicated in developmental and epileptic encephalopathy 105. [provided by Allia nce of Genome Resources, Jul 2025] | 17 | 74950742 | 74972759 | Human | 103 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1604777 | MND1 | meiotic nuclear divisions 1 | The product of the MND1 gene associates with HOP2 (MIM 608665) to form a stable heterodimeric complex that binds DNA and stimulates the recombinase activity of RAD51 (MIM 179617) and DMC1 (MIM 602721) (Chi et al., 2007 [PubMed 17639080]). Both the MND1 and HOP2 genes are indispensable for meiotic recombination.[supplied by OMIM, Mar 2008] | 4 | 153344649 | 153415118 | Human | 117 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 730859 | PSMC3IP | PSMC3 interacting protein | This gene encodes a protein that functions in meiotic recombination. It is a subunit of the PSMC3IP/MND1 complex, which interacts with PSMC3/TBP1 to stimulate DMC1- and RAD51-mediated strand exchange during meiosis. The protein encoded by this gene can also co-a ctivate ligand-driven transcription mediated by estrogen, androgen, glucocorticoid, progesterone, and thyroid nuclear receptors. Mutations in this gene cause XX female gonadal dysgenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2011] | 17 | 42572310 | 42577831 | Human | 171 | description | gene, protein-coding, REVIEWED [RefSeq] |