Cilp Gene Search Result

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2 records found for search term Cilp

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1312971	CILP	cartilage intermediate layer protein	Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein (CILP), which increases in early osteoarthrosis cartilage. The encoded protein w ... (more) as thought to encode a protein precursor for two different proteins; an N-terminal CILP and a C-terminal homolog of NTPPHase, however, later studies identified no nucleotide pyrophosphatase phosphodiesterase (NPP) activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease. [provided by RefSeq, Sep 2010]	15	65194760	65211473	Human	92	symbol , COSMIC , description , Human Proteome Map , old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]
1322465	CILP2	cartilage intermediate layer protein 2	Located in extracellular exosome. [provided by Alliance of Genome Resources, Jul 2025]	19	19538265	19546659	Human	56	symbol , COSMIC , Human Proteome Map , old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]