| 1351452 | ZPBP | zona pellucida binding protein | ZPBP is one of several proteins that are thought to participate in secondary binding between acrosome-reacted sperm and the egg-specific extracellular matrix, the zona pellucida (McLeskey et al., 1998 [PubMed 9378618]).[supplied by OMIM, Aug 2008] | 7 | 49840654 | 50093246 | Human | 48 | symbol , COSMIC , description , Human Proteome Map , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1557380 | Zpbp | zona pellucida binding protein | Acts upstream of or within acrosome assembly and binding activity of sperm to zona pellucida. Located in acrosomal vesicle and cell body. Part of zona pellucida receptor complex. Human ortholog(s) of this gene implicated in spermatogenic failure 66. Orthologous to human ZPBP '>ZPBP (zona pellucida binding protein). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 11229624 | 11414222 | Mouse | 58 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1563985 | Zpbp | zona pellucida binding protein | INVOLVED IN acrosome assembly (ortholog); binding of sperm to zona pellucida (ortholog); ASSOCIATED WITH spermatogenic failure 66 (ortholog); FOUND IN acrosomal vesicle (ortholog); cell body (ortholog); zona pellucida receptor complex (ortholog); INTERACTS WITH aflatoxin B1; DDT; endosulfan | 14 | 90047207 | 90244727 | Rat | 43 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8788336 | Zpbp | zona pellucida binding protein | INVOLVED IN acrosome assembly (ortholog); binding of sperm to zona pellucida (ortholog); ASSOCIATED WITH spermatogenic failure 66 (ortholog); FOUND IN acrosomal vesicle (ortholog); cell body (ortholog); zona pellucida receptor complex (ortholog) | NW_004955456 | 3887746 | 3935541 | Chinchilla | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12029715 | ZPBP | zona pellucida binding protein | INVOLVED IN acrosome assembly (ortholog); binding of sperm to zona pellucida (ortholog); ASSOCIATED WITH spermatogenic failure 66 (ortholog); FOUND IN cell body (ortholog) | 7 | 50576485 | 50735411 | Bonobo | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12065124 | ZPBP | zona pellucida binding protein | INVOLVED IN acrosome assembly (ortholog); binding of sperm to zona pellucida (ortholog); ASSOCIATED WITH spermatogenic failure 66 (ortholog); FOUND IN cell body (ortholog) | 18 | 1374312 | 1461722 | Dog | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12577820 | Zpbp | zona pellucida binding protein | INVOLVED IN acrosome assembly (ortholog); binding of sperm to zona pellucida (ortholog); ASSOCIATED WITH spermatogenic failure 66 (ortholog); FOUND IN cell body (ortholog) | NW_004936686 | 1742290 | 1842998 | Squirrel | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14081682 | ZPBP | zona pellucida binding protein | INVOLVED IN acrosome assembly (ortholog); binding of sperm to zona pellucida (ortholog); ASSOCIATED WITH spermatogenic failure 66 (ortholog); FOUND IN cell body (ortholog) | | | | Pig | 17 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 18394937 | ZPBP | zona pellucida binding protein | INVOLVED IN acrosome assembly (ortholog); binding of sperm to zona pellucida (ortholog); ASSOCIATED WITH spermatogenic failure 66 (ortholog); FOUND IN cell body (ortholog) | | | | Green Monkey | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18920245 | Zpbp | zona pellucida binding protein | INVOLVED IN acrosome assembly (ortholog); binding of sperm to zona pellucida (ortholog); ASSOCIATED WITH spermatogenic failure 66 (ortholog); FOUND IN cell body (ortholog) | | | | Naked Mole-Rat | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625980690 | Zpbp | zona pellucida binding protein | INVOLVED IN acrosome assembly (ortholog); binding of sperm to zona pellucida (ortholog); ASSOCIATED WITH spermatogenic failure 66 (ortholog); FOUND IN acrosomal vesicle (ortholog); cell body (ortholog); zona pellucida receptor complex (ortholog) | | | | Black Rat | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 16572605 | AC034148.1 | novel transcript, antisense to ZPBP | | | | | Human | | name | gene, lncrna |
| 1603918 | ZPBP2 | zona pellucida binding protein 2 | Predicted to be involved in acrosome assembly and binding activity of sperm to zona pellucida. Predicted to act upstream of or within membrane lipid metabolic process and regulation of gene expression. Located in nucleus. [provided by Alliance of Genome Resources, Jul 2025] | 17 | 39868202 | 39877896 | Human | 62 | symbol , old_gene_name , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1549726 | Zpbp2 | zona pellucida binding protein 2 | INVOLVED IN acrosome assembly (ortholog); binding of sperm to zona pellucida (ortholog); circadian regulation of gene expression (ortholog); ASSOCIATED WITH adult-onset asthma (ortholog); asthma (ortholog); atrial fibrillation (ortholog); FOUND IN acrosomal vesicle (ortholog); cell body (ortholog); zona pellucida receptor complex (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; amphetamine | 10 | 84055184 | 84063776 | Rat | 66 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1558392 | Zpbp2 | zona pellucida binding protein 2 | Acts upstream of or within several processes, including binding activity of sperm to zona pellucida; membrane lipid metabolic process; and regulation of gene expression. Located in acrosomal vesicle and cell body. Part of zona pellucida receptor complex. Is expressed in lung. Orthologous to human ... (more)pan style='font-weight:700;'>ZPBP2 (zona pellucida binding protein 2). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 98441923 | 98449491 | Mouse | 78 | symbol , PhenoGen , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 8831163 | Zpbp2 | zona pellucida binding protein 2 | INVOLVED IN acrosome assembly (ortholog); binding of sperm to zona pellucida (ortholog); circadian regulation of gene expression (ortholog); ASSOCIATED WITH adult-onset asthma (ortholog); asthma (ortholog); atrial fibrillation (ortholog); FOUND IN acrosomal vesicle (ortholog); cell body (ortholog); zona pellucida receptor complex (ortholog) | NW_004955451 | 14571707 | 14579890 | Chinchilla | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11995193 | ZPBP2 | zona pellucida binding protein 2 | INVOLVED IN acrosome assembly (ortholog); binding of sperm to zona pellucida (ortholog); circadian regulation of gene expression (ortholog); ASSOCIATED WITH adult-onset asthma (ortholog); atrial fibrillation (ortholog); lung squamous cell carcinoma (ortholog); FOUND IN acrosomal vesicle (inferred); cell body (inferred); cytoplasmic vesicle (inferred) | 17 | 17410278 | 17420458 | Bonobo | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12272428 | ZPBP2 | zona pellucida binding protein 2 | INVOLVED IN acrosome assembly (ortholog); binding of sperm to zona pellucida (ortholog); circadian regulation of gene expression (ortholog); ASSOCIATED WITH adult-onset asthma (ortholog); asthma (ortholog); atrial fibrillation (ortholog); FOUND IN acrosomal vesicle (inferred); cell body (inferred); cytoplasmic vesicle (inferred) | 9 | 22632114 | 22639507 | Dog | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12470292 | Zpbp2 | zona pellucida binding protein 2 | INVOLVED IN acrosome assembly (ortholog); binding of sperm to zona pellucida (ortholog); circadian regulation of gene expression (ortholog); ASSOCIATED WITH adult-onset asthma (ortholog); asthma (ortholog); atrial fibrillation (ortholog); FOUND IN acrosomal vesicle (inferred); cell body (inferred); cytoplasmic vesicle (inferred) | NW_004936490 | 15029447 | 15038046 | Squirrel | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14025857 | ZPBP2 | zona pellucida binding protein 2 | INVOLVED IN acrosome assembly (ortholog); binding of sperm to zona pellucida (ortholog); circadian regulation of gene expression (ortholog); ASSOCIATED WITH adult-onset asthma (ortholog); asthma (ortholog); atrial fibrillation (ortholog); FOUND IN acrosomal vesicle (inferred); cell body (inferred); cytoplasmic vesicle (inferred) | | | | Pig | 30 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 18579514 | ZPBP2 | zona pellucida binding protein 2 | INVOLVED IN acrosome assembly (ortholog); binding of sperm to zona pellucida (ortholog); circadian regulation of gene expression (ortholog); ASSOCIATED WITH adult-onset asthma (ortholog); asthma (ortholog); atrial fibrillation (ortholog); FOUND IN acrosomal vesicle (ortholog); cell body (ortholog); zona pellucida receptor complex (ortholog) | | | | Green Monkey | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18932366 | Zpbp2 | zona pellucida binding protein 2 | INVOLVED IN acrosome assembly (ortholog); binding of sperm to zona pellucida (ortholog); circadian regulation of gene expression (ortholog); ASSOCIATED WITH adult-onset asthma (ortholog); atrial fibrillation (ortholog); lung squamous cell carcinoma (ortholog); FOUND IN cell body (ortholog) | | | | Naked Mole-Rat | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 329329235 | zpbp2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626124837 | Zpbp2 | zona pellucida binding protein 2 | INVOLVED IN acrosome assembly (ortholog); binding of sperm to zona pellucida (ortholog); circadian regulation of gene expression (ortholog); ASSOCIATED WITH adult-onset asthma (ortholog); atrial fibrillation (ortholog); lung squamous cell carcinoma (ortholog); FOUND IN acrosomal vesicle (ortholog); cell body (ortholog); zona pellucida receptor complex (ortholog) | | | | Black Rat | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 284349263 | zpbp2.L | | | | | | African Clawed Frog | | symbol | gene, null |