ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN negative regulation of epidermal growth factor receptor signaling pathway (ortholog); negative regulation of toll-like receptor signaling pathway (ortholog); p
rotein autoubiquitination (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); FOUND IN cytosol (ortholog); endoplasmic reticulum (ortholog); INTERACTS WITH acetamide; bisphenol A; flutamide
Enables ubiquitin protein ligase activity. Involved in negative regulation of signal transduction; protein ubiquitination; and ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Is active in endoplasmic reticulum. [provided by Alliance of Genome Resources, Jul
Enables ubiquitin protein ligase activity. Involved in protein K48-linked ubiquitination and protein K63-linked ubiquitination. Located in cytosol. Is expressed in central nervous system and genitourinary system. Orthologous to human RNF115 (ring finger protein 115). [provided by Alliance of Genome