ENCODES a protein that exhibits DNA-binding transcription factor activity; INVOLVED IN kidney development; negative regulation of transcription by RNA polymerase II; nucleolus organization; ASSOCIATED WITH Reperfusion Injury; in situ carcinoma (ortholog); seminoma (ortholog); FOUND IN nucleolus (ort
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and nucleolus organization. Predicted to
be located in cytosol; nucleolus; and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and liver and biliary system. Orthologous to human ZNF354A (zinc finger protein 354A). [provided by Alliance of Genome Resources, Jul 2025]