ENCODES a protein that exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); sequence-specific DNA binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); p
ositive regulation of transcription by RNA polymerase II (ortholog); FOUND IN cytosol (ortholog); nucleus (ortholog); INTERACTS WITH amitrole; bisphenol A; cadmium dichloride
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcript
ion by RNA polymerase II. Located in nucleus. Is expressed in central nervous system; early conceptus; and genitourinary system. Orthologous to human ZNF263 (zinc finger protein 263). [provided by Alliance of Genome Resources, Jul 2025]