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78 records found for search term Wfdc1
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
68938Wfdc1WAP four-disulfide core domain 1ENCODES a protein that exhibits peptidase inhibitor activity (inferred); serine-type endopeptidase inhibitor activity (inferred); INVOLVED IN negative regulation of epithelial cell proliferation; regulation of cell growth; response to estradiol; ASSOCIATED WITH COVID-19 (ortholog); melanoma (ortholo196462868964647739Rat105symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
68974WFDC1WAP four-disulfide core domain 1This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is mapped to chromosome 16q2168429487884329844Human107symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
68975Wfdc1WAP four-disulfide core domain 1Predicted to enable serine-type endopeptidase inhibitor activity. Acts upstream of or within negative regulation of inflammatory response and negative regulation of wound healing. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in eye; mal8120393104120414759Mouse114symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
9047660Wfdc1WAP four-disulfide core domain 1INVOLVED IN negative regulation of epithelial cell proliferation (ortholog); negative regulation of inflammatory response (ortholog); negative regulation of wound healing (ortholog); ASSOCIATED WITH COVID-19 (ortholog); melanoma (ortholog); prostate cancer (ortholog); FOUND IN extracellular space (oNW_0049555642253638091Chinchilla11symbolgene, protein-coding, MODEL [RefSeq]
11981705WFDC1WAP four-disulfide core domain 1ENCODES a protein that exhibits peptidase inhibitor activity (inferred); serine-type endopeptidase inhibitor activity (inferred); INVOLVED IN negative regulation of epithelial cell proliferation (ortholog); negative regulation of inflammatory response (ortholog); negative regulation of wound healing166495892064994314Bonobo18symbolgene, protein-coding, MODEL [RefSeq]
12362862WFDC1WAP four-disulfide core domain 1ENCODES a protein that exhibits peptidase inhibitor activity (inferred); serine-type endopeptidase inhibitor activity (inferred); INVOLVED IN negative regulation of epithelial cell proliferation (ortholog); negative regulation of inflammatory response (ortholog); negative regulation of wound healing56806789468095749Dog18symbolgene, protein-coding, MODEL [RefSeq]
13991584WFDC1WAP four-disulfide core domain 1ENCODES a protein that exhibits peptidase inhibitor activity (inferred); serine-type endopeptidase inhibitor activity (inferred); INVOLVED IN negative regulation of epithelial cell proliferation (ortholog); negative regulation of inflammatory response (ortholog); negative regulation of wound healingPig21symbolgene, protein-coding, VALIDATED [RefSeq]
18382372WFDC1WAP four-disulfide core domain 1ENCODES a protein that exhibits peptidase inhibitor activity (inferred); serine-type endopeptidase inhibitor activity (inferred); INVOLVED IN negative regulation of epithelial cell proliferation (ortholog); negative regulation of inflammatory response (ortholog); negative regulation of wound healingGreen Monkey18symbolgene, protein-coding, MODEL [RefSeq]
39131316WFDC1WAP four-disulfide core domain 1Chinchillasymbolgene, protein-coding
152178138WFDC1WAP four-disulfide core domain 1Naked Mole-Ratsymbolgene, protein-coding
155238492wfdc1Tropical Clawed Frogsymbolgene, null
155258089wfdc1.LAfrican Clawed Frogsymbolgene, null
155246547wfdc1.SAfrican Clawed Frogsymbolgene, null
18919436LOC101710653kelch domain-containing protein 4ENCODES a protein that exhibits peptidase inhibitor activity (inferred); serine-type endopeptidase inhibitor activity (inferred); FOUND IN extracellular region (inferred)Naked Mole-Rat5old_gene_symbolgene, protein-coding, MODEL [RefSeq]
16562796AC010551.2novel transcript, antisense to WFDC1Humannamegene, lncrna
1619500Wfdc10WAP four-disulfide core domain 10Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in antibacterial humoral response and innate immune response. Predicted to be active in extracellular space. Orthologous to several human genes including WFDC10A (WAP four2164497966164499288Mouse32symbol , PhenoGen , descriptiongene, protein-coding, PROVISIONAL [RefSeq]
1351256WFDC11WAP four-disulfide core domain 11This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20204564856345670239Human18symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1596469Wfdc11WAP four-disulfide core domain 11INTERACTS WITH bisphenol A; manganese(II) chloride; trichloroethene3173816904173825765Rat13symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
2295209Wfdc11WAP four-disulfide core domain 11Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in antibacterial humoral response and innate immune response. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human WFDC12164504814164516011Mouse18symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
11953583WFDC11WAP four-disulfide core domain 11204198331342003292Bonobosymbolgene, protein-coding, MODEL [RefSeq]
12399500WFDC11WAP four-disulfide core domain 11243295226833002489Dogsymbolgene, protein-coding, MODEL [RefSeq]
13858367WFDC11WAP four-disulfide core domain 11Pigsymbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
19259593WFDC11WAP four-disulfide core domain 11Dogsymbolgene, protein-coding
124769627Wfdc11WAP four-disulfide core domain 11Squirrelsymbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
150657717WFDC11Dog4symbolgene, protein-coding
155263542WFDC11WAP four-disulfide core domain 11Squirrelsymbolgene, protein-coding
1303229Wfdc12WAP four-disulfide core domain 12ENCODES a protein that exhibits peptidase inhibitor activity (inferred); serine-type endopeptidase inhibitor activity (inferred); INVOLVED IN defense response to bacterium (ortholog); FOUND IN extracellular region (inferred); INTERACTS WITH 3,4-methylenedioxymethamphetamine; 3-chloropropane-1,2-diol3173280844173282167Rat48symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1349049WFDC12WAP four-disulfide core domain 12This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20204512342545124465Human47symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1551325Wfdc12WAP four-disulfide core domain 12Predicted to enable serine-type endopeptidase inhibitor activity. Involved in defense response to bacterium. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human WFDC12 (WAP four-disulfide core doma2164031151164032528Mouse46symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
11989481WFDC12WAP four-disulfide core domain 12ENCODES a protein that exhibits peptidase inhibitor activity (inferred); serine-type endopeptidase inhibitor activity (inferred); INVOLVED IN defense response to bacterium (inferred); FOUND IN extracellular region (inferred)204145328241454943Bonobo7symbolgene, protein-coding, MODEL [RefSeq]
18782376WFDC12WAP four-disulfide core domain 12ENCODES a protein that exhibits peptidase inhibitor activity (inferred); serine-type endopeptidase inhibitor activity (inferred); INVOLVED IN defense response to bacterium (inferred); FOUND IN extracellular region (inferred)Green Monkey7symbolgene, protein-coding, MODEL [RefSeq]
20867064WFDC12WAP four-disulfide core domain 12Green Monkeysymbolgene, protein-coding
1352525WFDC13WAP four-disulfide core domain 13This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20204570203845708817Human22symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1613955Wfdc13WAP four-disulfide core domain 13Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in antibacterial humoral response and innate immune response. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human WFDC12164527027164529626Mouse22symbol , PhenoGen , description , old_gene_symbolgene, protein-coding, PROVISIONAL [RefSeq]
2319575Wfdc13WAP four-disulfide core domain 13INTERACTS WITH 17beta-estradiol; testosterone; tetrachloromethane3173838906173840641Rat15symbol , PhenoGengene, protein-coding, MODEL [RefSeq]
11713476WFDC13WAP four-disulfide core domain 13204204074642047823Bonobo1symbolgene, protein-coding, MODEL [RefSeq]
12336350WFDC13WAP four-disulfide core domain 13243301120233029260Dog1symbolgene, protein-coding, MODEL [RefSeq]
12594800Wfdc13WAP four-disulfide core domain 13NW_00493651472915487294083Squirrel1symbolgene, protein-coding, MODEL [RefSeq]
14186825WFDC13WAP four-disulfide core domain 13Pig1symbolgene, protein-coding, MODEL [RefSeq]
18424093WFDC13WAP four-disulfide core domain 13Green Monkey1symbolgene, protein-coding, MODEL [RefSeq]
20867080WFDC13WAP four-disulfide core domain 13Green Monkeysymbolgene, protein-coding
150657719WFDC13WAP four-disulfide core domain 13Dog4symbolgene, protein-coding
626033118Wfdc13WAP four-disulfide core domain 13Black Rat1symbolgene, protein-coding, MODEL [RefSeq]
1596495Wfdc16WAP four-disulfide core domain 16ENCODES a protein that exhibits peptidase inhibitor activity (inferred); FOUND IN extracellular region (inferred); INTERACTS WITH bisphenol A; methoxychlor3173786248173789418Rat8symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1620482Wfdc16WAP four-disulfide core domain 16Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in antibacterial humoral response and innate immune response. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Jul 2025]2164476621164480728Mouse19symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1624871Wfdc17WAP four-disulfide core domain 17Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in antibacterial humoral response and innate immune response. Predicted to be active in extracellular space. Is expressed in several structures, including adipose tissue; bone; liver; lung; and spleen. [provid118359488283597095Mouse43symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
2318138Wfdc17WAP four-disulfide core domain 17ENCODES a protein that exhibits serine-type endopeptidase inhibitor activity (ortholog); ASSOCIATED WITH amenorrhea (ortholog); Delayed Puberty (ortholog); genetic disease (ortholog); INTERACTS WITH bisphenol A; trichloroethene; (1->4)-beta-D-glucan (ortholog)106905945169060298Rat94symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
619957Wfdc18WAP four-disulfide core domain 18ENCODES a protein that exhibits peptidase inhibitor activity (inferred); ASSOCIATED WITH Neoplasm Metastasis; FOUND IN extracellular region (inferred); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl106908631969088473Rat58symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
737112Wfdc18WAP four-disulfide core domain 18Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in antibacterial humoral response and innate immune response. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in mammary gland. [provided by Allianc118359983083602186Mouse59symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1315782WFDC10AWAP four-disulfide core domain 10AThis gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20204562973945631196Human35symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1596480Wfdc10aWAP four-disulfide core domain 10AENCODES a protein that exhibits peptidase inhibitor activity (inferred); FOUND IN extracellular region (inferred); INTERACTS WITH 6-propyl-2-thiouracil; all-trans-retinoic acid; bisphenol A3173809395173810748Rat33symbol , PhenoGen , old_gene_symbolgene, protein-coding, PROVISIONAL [RefSeq]
11962683WFDC10AWAP four-disulfide core domain 10A204196631441967804Bonobosymbolgene, protein-coding, MODEL [RefSeq]
12257998WFDC10AWAP four-disulfide core domain 10AENCODES a protein that exhibits peptidase inhibitor activity (inferred); FOUND IN extracellular region (inferred)243290950532910890Dog6symbolgene, protein-coding, MODEL [RefSeq]
18573721WFDC10AWAP four-disulfide core domain 10AENCODES a protein that exhibits peptidase inhibitor activity (inferred); FOUND IN extracellular region (inferred)Green Monkey2symbolgene, protein-coding, MODEL [RefSeq]
18915072Wfdc10aWAP four-disulfide core domain 10AENCODES a protein that exhibits peptidase inhibitor activity (inferred); FOUND IN extracellular region (inferred)Naked Mole-Rat2symbolgene, protein-coding, MODEL [RefSeq]
626081562Wfdc10aWAP four-disulfide core domain 10ABlack Ratsymbolgene, protein-coding, MODEL [RefSeq]
1343114WFDC10BWAP four-disulfide core domain 10BThis gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20204568465145705019Human14symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
11673546WFDC10BWAP four-disulfide core domain 10B204201771242019309Bonobo1symbolgene, protein-coding, MODEL [RefSeq]
12081262WFDC10BWAP four-disulfide core domain 10BENCODES a protein that exhibits peptidase inhibitor activity (inferred); FOUND IN extracellular region (inferred)243300420933006293Dog3symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
18676425WFDC10BWAP four-disulfide core domain 10BGreen Monkey1symbolgene, protein-coding, MODEL [RefSeq]
1303026Wfdc15aWAP four-disulfide core domain 15AENCODES a protein that exhibits peptidase inhibitor activity (inferred); FOUND IN extracellular region (inferred); INTERACTS WITH bisphenol A3173292668173294900Rat3symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1550404Wfdc15aWAP four-disulfide core domain 15APredicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in antibacterial humoral response and innate immune response. Predicted to be located in extracellular region. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Jul 20252164040783164042058Mouse30symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1303042Wfdc15bWAP four-disulfide core domain 15BENCODES a protein that exhibits peptidase inhibitor activity (inferred); serine-type endopeptidase inhibitor activity (inferred); FOUND IN extracellular region (inferred); INTERACTS WITH acetamide; amphetamine; bisphenol A3173308835173318772Rat12symbol , PhenoGen , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1550456Wfdc15bWAP four-disulfide core domain 15BPredicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in antibacterial humoral response and innate immune response. Predicted to be located in extracellular region. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Jul 20252164056374164063583Mouse28symbol , PhenoGen , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
14115030WFDC10ALWAP four-disulfide core domain 10A-likePig4symbolgene, protein-coding, MODEL [RefSeq]
6502228Wfdc18l1WAP four-disulfide core domain 18 like 1106903654069038674Ratsymbol , PhenoGengene, protein-coding, MODEL [RefSeq]
1350490ANOS1anosmin 1Mutations in this gene cause the X-linked Kallmann syndrome. The encoded protein is similar in sequence to proteins known to function in neural cell adhesion and axonal migration. In addition, this cell surface protein is N-glycosylated and may have anti-protease activity. [provided by RefSeq, Jul 2X85288748732137Human212old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
18910104LOC101703307WAP four-disulfide core domain protein 15AENCODES a protein that exhibits peptidase inhibitor activity (inferred); FOUND IN extracellular region (inferred)Naked Mole-Rat2old_gene_symbolgene, protein-coding, MODEL [RefSeq]
13140894LOC110598145WAP four-disulfide core domain protein 15AENCODES a protein that exhibits peptidase inhibitor activity (inferred); INVOLVED IN defense response to bacterium (ortholog); FOUND IN extracellular region (inferred)NW_00493651476501147651139Squirrel4old_gene_symbolgene, protein-coding, MODEL [RefSeq]
1344308PI3peptidase inhibitor 3This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria, and fungal pathogens. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene member204517490245176544Human78old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
14139303LOC100621271WAP four-disulfide core domain protein 10AENCODES a protein that exhibits peptidase inhibitor activity (inferred); FOUND IN extracellular region (inferred)Pig6ensembl_gene_symbol , old_gene_symbolgene, protein-coding, MODEL [RefSeq]
8959704LOC102003392WAP four-disulfide core domain protein 10ANW_0049554451163430911635726Chinchillaold_gene_symbolgene, protein-coding, MODEL [RefSeq]
625980008LOC116900772protein WFDC11-likeBlack Ratnamegene, protein-coding, MODEL [RefSeq]
12734485LOC101974474protein WFDC10B-likeNW_00493651473557617358427Squirrelnamegene, protein-coding, MODEL [RefSeq]
124752433LOC120886829protein WFDC10B-likeSquirrelnamegene, protein-coding, MODEL [RefSeq]
16555592AL035660.1WAP four-disulfide core domain 15B (Wfdc15b) pseudogeneHumannamegene, unprocessed_pseudogene
40923402LOC119863887WAP four-disulfide core domain protein 10A-likeENCODES a protein that exhibits peptidase inhibitor activity (inferred); FOUND IN extracellular region (inferred)Dog6old_gene_namegene, protein-coding, MODEL [RefSeq]
38650088LOC105372630uncharacterized LOC105372630204523083745290352Humanold_gene_namegene, ncrna, MODEL [RefSeq]