| 1311255 | Ttll3 | tubulin tyrosine ligase like 3 | ENCODES a protein that exhibits protein-glycine ligase activity (ortholog); protein-glycine ligase activity, initiating (ortholog); INVOLVED IN cilium assembly (ortholog); flagellated sperm motility (ortholog); protein polyglycylation (ortholog); FOUND IN axoneme (ortholog); cilium (ortholog); micro tubule cytoskeleton (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide | 4 | 148088575 | 148113526 | Rat | 91 | symbol , old_gene_name , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1322614 | TTLL3 | tubulin tyrosine ligase like 3 | Enables protein-glycine ligase activity. Predicted to be involved in several processes, including axoneme assembly; flagellated sperm motility; and protein polyglycylation. Predicted to be located in cilium. Predicted to be active in axoneme; microtubule cytoskeleton; and sperm flagellum. [provided by Alliance of Genome Resources, Jul 2025] | 3 | 9809727 | 9836365 | Human | 99 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1615777 | Ttll3 | tubulin tyrosine ligase-like family, member 3 | Enables protein-glycine ligase activity, initiating. Involved in flagellated sperm motility and protein polyglycylation. Acts upstream of or within cilium assembly. Located in axoneme; microtubule cytoskeleton; and sperm flagellum. Is expressed in midbrain ventricular layer; node; and pons ventricul ar layer. Orthologous to human TTLL3 (tubulin tyrosine ligase like 3). [provided by Alliance of Genome Resources, Jul 2025] | 6 | 113366221 | 113391553 | Mouse | 119 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8899060 | Ttll3 | tubulin tyrosine ligase like 3 | ENCODES a protein that exhibits protein-glycine ligase activity (ortholog); protein-glycine ligase activity, initiating (ortholog); INVOLVED IN cilium assembly (ortholog); flagellated sperm motility (ortholog); protein polyglycylation (ortholog); FOUND IN axoneme (ortholog); cilium (ortholog); micro tubule cytoskeleton (ortholog) | NW_004955561 | 1330378 | 1353217 | Chinchilla | 13 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11725041 | TTLL3 | tubulin tyrosine ligase like 3 | ENCODES a protein that exhibits protein-glycine ligase activity (ortholog); INVOLVED IN cilium assembly (ortholog); flagellated sperm motility (ortholog); protein polyglycylation (ortholog); FOUND IN cilium (ortholog); sperm flagellum (ortholog) | 3 | 9759871 | 9786690 | Bonobo | 17 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12112472 | TTLL3 | tubulin tyrosine ligase like 3 | ENCODES a protein that exhibits protein-glycine ligase activity (ortholog); INVOLVED IN cilium assembly (ortholog); protein polyglycylation (ortholog); FOUND IN axoneme (ortholog); cilium (ortholog); microtubule cytoskeleton (ortholog) | 20 | 8414289 | 8439071 | Dog | 20 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 155246012 | ttll3 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 41412207 | TTLL3 | tubulin tyrosine ligase like 3 | | | | | Green Monkey | | symbol | gene, protein-coding |
| 14232481 | TTLL3 | tubulin tyrosine ligase like 3 | ENCODES a protein that exhibits protein-glycine ligase activity (ortholog); INVOLVED IN cilium assembly (ortholog); protein polyglycylation (ortholog); FOUND IN axoneme (ortholog); cilium (ortholog); microtubule cytoskeleton (ortholog) | | | | Pig | 26 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 626105223 | Ttll3 | tubulin tyrosine ligase like 3 | ENCODES a protein that exhibits protein-glycine ligase activity (ortholog); protein-glycine ligase activity, initiating (ortholog); INVOLVED IN cilium assembly (ortholog); flagellated sperm motility (ortholog); protein polyglycylation (ortholog); FOUND IN axoneme (ortholog); cilium (ortholog); micro tubule cytoskeleton (ortholog) | | | | Black Rat | 13 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18496860 | TTLL3 | tubulin tyrosine ligase like 3 | ENCODES a protein that exhibits protein-glycine ligase activity (ortholog); INVOLVED IN cilium assembly (ortholog); flagellated sperm motility (ortholog); protein polyglycylation (ortholog); FOUND IN cilium (ortholog); sperm flagellum (ortholog) | | | | Green Monkey | 17 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 5013864 | ARPC4-TTLL3 | ARPC4-TTLL3 readthrough | This locus represents naturally occurring read-through transcription between the neighboring ARPC4 (actin related protein 2/3 complex, subunit 4) and TTLL3 (tubulin tyrosine ligase-like family, member 3) genes. The read-through transcript encodes a fusion protei n that shares sequence identity with each individual gene product. [provided by RefSeq, Nov 2010] | 3 | 9792548 | 9836356 | Human | 17 | symbol , old_gene_name , COSMIC , name , description , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 18919239 | LOC101698131 | actin-related protein 2/3 complex subunit 4 | ENCODES a protein that exhibits acid-amino acid ligase activity (inferred); actin binding (inferred); actin filament binding (inferred); INVOLVED IN actin filament polymerization (inferred); Arp2/3 complex-mediated actin nucleation (inferred); cilium assembly (inferred); FOUND IN actin cytoskeleton (inferred); Arp2/3 protein complex (inferred); axoneme (inferred) | | | | Naked Mole-Rat | 22 | old_gene_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12645670 | LOC101960992 | actin-related protein 2/3 complex subunit 4 | ENCODES a protein that exhibits actin binding (inferred); actin filament binding (inferred); ATP binding (inferred); INVOLVED IN actin filament polymerization (inferred); Arp2/3 complex-mediated actin nucleation (inferred); cilium assembly (inferred); FOUND IN actin cytoskeleton (inferred); Arp2/3 p rotein complex (inferred); axoneme (inferred) | NW_004936602 | 3340215 | 3363576 | Squirrel | 28 | old_gene_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 16565276 | AC022382.1 | novel transcript, antisense to TTLL3 | | | | | Human | | name | gene, lncrna |
| 14388689 | TTLL3A | | | | | | Fly | | symbol | gene, null |
| 14381342 | TTLL3B | | | | | | Fly | | symbol | gene, null |
| 1320803 | ARPC4 | actin related protein 2/3 complex subunit 4 | This gene encodes one of seven subunits of the human Arp2/3 protein complex. This complex controls actin polymerization in cells and has been conserved throughout eukaryotic evolution. This gene encodes the p20 subunit, which is necessary for actin nucleation and high-affinity binding to F-actin. Al ternative splicing results in multiple transcript variants. Naturally occurring read-through transcription exists between this gene and the downstream tubulin tyrosine ligase-like family, member 3 (TTLL3), which results in the production of a fusion protein. [provided by RefSeq, Nov 2010] | 3 | 9792518 | 9807101 | Human | 147 | description | gene, protein-coding, REVIEWED [RefSeq] |