| 1566388 | Trim71 | tripartite motif containing 71 | ENCODES a protein that exhibits miRNA binding (ortholog); translation repressor activity (ortholog); ubiquitin protein ligase activity (ortholog); INVOLVED IN 3'-UTR-mediated mRNA destabilization (ortholog); fibroblast growth factor receptor signaling pathway (ortholog); G1/S transition of mitotic c ell cycle (ortholog); ASSOCIATED WITH Congenital Communicating Hydrocephalus 1 (ortholog); COVID-19 (ortholog); CRYPTOZOOSPERMIA (ortholog); FOUND IN P-body (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; atrazine; bisphenol A | 8 | 123076499 | 123129016 | Rat | 98 | symbol , old_gene_name , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1606726 | TRIM71 | tripartite motif containing 71 | The protein encoded by this gene is an E3 ubiquitin-protein ligase that binds with miRNAs and maintains the growth and upkeep of embryonic stem cells. This gene also is involved in the G1-S phase transition of the cell cycle. [provided by RefSeq, Dec 2015] | 3 | 32817997 | 32897824 | Human | 115 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1613794 | Trim71 | tripartite motif-containing 71 | Enables miRNA binding activity and ubiquitin protein ligase activity. Involved in several processes, including G1/S transition of mitotic cell cycle; miRNA-mediated gene silencing by inhibition of translation; and protein autoubiquitination. Acts upstream of or within neural tube closure; positive r egulation of miRNA-mediated gene silencing; and regulation of protein metabolic process. Located in P-body. Is expressed in several structures, including branchial arch; extraembryonic component; limb bud; nervous system; and reproductive system. Used to study hydrocephalus. Human ortholog(s) of this gene implicated in hydrocephalus. Orthologous to human TRIM71 (tripartite motif containing 71). [provided by Alliance of Genome Resources, Jul 2025] | 9 | 114340336 | 114393437 | Mouse | 134 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8797223 | Trim71 | tripartite motif containing 71 | ENCODES a protein that exhibits miRNA binding (ortholog); translation repressor activity (ortholog); ubiquitin protein ligase activity (ortholog); INVOLVED IN 3'-UTR-mediated mRNA destabilization (ortholog); fibroblast growth factor receptor signaling pathway (ortholog); G1/S transition of mitotic c ell cycle (ortholog); ASSOCIATED WITH Congenital Communicating Hydrocephalus 1 (ortholog); COVID-19 (ortholog); CRYPTOZOOSPERMIA (ortholog); FOUND IN P-body (ortholog) | NW_004955421 | 97130 | 174326 | Chinchilla | 31 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11897052 | TRIM71 | tripartite motif containing 71 | ENCODES a protein that exhibits metal ion binding (inferred); miRNA binding (inferred); RNA binding (inferred); INVOLVED IN neural tube closure (ortholog); positive regulation of miRNA-mediated gene silencing (ortholog); post-transcriptional regulation of gene expression (ortholog); ASSOCIATED WITH Congenital Communicating Hydrocephalus 1 (ortholog); COVID-19 (ortholog); CRYPTOZOOSPERMIA (ortholog); FOUND IN P-body (inferred) | 3 | 32745217 | 32824985 | Bonobo | 44 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12308511 | TRIM71 | tripartite motif containing 71 | ENCODES a protein that exhibits metal ion binding (inferred); miRNA binding (inferred); RNA binding (inferred); INVOLVED IN neural tube closure (ortholog); positive regulation of miRNA-mediated gene silencing (ortholog); post-transcriptional regulation of gene expression (ortholog); ASSOCIATED WITH Congenital Communicating Hydrocephalus 1 (ortholog); COVID-19 (ortholog); CRYPTOZOOSPERMIA (ortholog); FOUND IN cytoplasm (inferred); P-body (inferred) | 23 | 3888287 | 3959910 | Dog | 49 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12451016 | Trim71 | tripartite motif containing 71 | ENCODES a protein that exhibits metal ion binding (inferred); miRNA binding (inferred); RNA binding (inferred); INVOLVED IN neural tube closure (ortholog); positive regulation of miRNA-mediated gene silencing (ortholog); post-transcriptional regulation of gene expression (ortholog); ASSOCIATED WITH Congenital Communicating Hydrocephalus 1 (ortholog); COVID-19 (ortholog); CRYPTOZOOSPERMIA (ortholog); FOUND IN P-body (inferred) | NW_004936473 | 23223984 | 23290177 | Squirrel | 45 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 155238632 | trim71 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14180687 | TRIM71 | tripartite motif containing 71 | ENCODES a protein that exhibits metal ion binding (inferred); miRNA binding (inferred); RNA binding (inferred); INVOLVED IN neural tube closure (ortholog); positive regulation of miRNA-mediated gene silencing (ortholog); post-transcriptional regulation of gene expression (ortholog); ASSOCIATED WITH Congenital Communicating Hydrocephalus 1 (ortholog); COVID-19 (ortholog); CRYPTOZOOSPERMIA (ortholog); FOUND IN cytoplasm (inferred); P-body (inferred) | | | | Pig | 49 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18461513 | TRIM71 | tripartite motif containing 71 | ENCODES a protein that exhibits metal ion binding (inferred); miRNA binding (inferred); RNA binding (inferred); INVOLVED IN neural tube closure (ortholog); positive regulation of miRNA-mediated gene silencing (ortholog); post-transcriptional regulation of gene expression (ortholog); ASSOCIATED WITH Congenital Communicating Hydrocephalus 1 (ortholog); COVID-19 (ortholog); CRYPTOZOOSPERMIA (ortholog); FOUND IN P-body (inferred) | | | | Green Monkey | 45 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 626096067 | Trim71 | tripartite motif containing 71 | ENCODES a protein that exhibits miRNA binding (ortholog); translation repressor activity (ortholog); ubiquitin protein ligase activity (ortholog); INVOLVED IN 3'-UTR-mediated mRNA destabilization (ortholog); fibroblast growth factor receptor signaling pathway (ortholog); G1/S transition of mitotic c ell cycle (ortholog); ASSOCIATED WITH Congenital Communicating Hydrocephalus 1 (ortholog); COVID-19 (ortholog); CRYPTOZOOSPERMIA (ortholog); FOUND IN P-body (ortholog) | | | | Black Rat | 31 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18929520 | Trim71 | tripartite motif containing 71 | ENCODES a protein that exhibits translation repressor activity (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN 3'-UTR-mediated mRNA destabilization (ortholog); fibroblast growth factor receptor signaling pathway (ortholog); G1/S transition of mitotic cell cycle (ortholog); ASSOCIATED WITH Congenital Communicating Hydrocephalus 1 (ortholog); COVID-19 (ortholog); CRYPTOZOOSPERMIA (ortholog); FOUND IN P-body (inferred) | | | | Naked Mole-Rat | 41 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 405858391 | trim71.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 626186728 | trim71.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405864482 | trim71.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405865527 | trim71.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405864623 | trim71.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155243720 | trim71.S | | | | | | African Clawed Frog | | symbol | gene, null |