| 1320807 | TPD52L1 | TPD52 like 1 | This gene encodes a member of a family of proteins that contain coiled-coil domains and may form hetero- or homomers. The encoded protein is involved in cell proliferation and calcium signaling. It also interacts with the mitogen-activated protein kinase kinase kinase 5 (MAP3K5/ASK1) and positively regulates MAP3K5-induced apoptosis. Multiple alternatively spliced transcript variants have been observed. [provided by RefSeq, Jan 2016] | 6 | 125153773 | 125264407 | Human | 173 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1320808 | Tpd52l1 | tumor protein D52-like 1 | Predicted to enable protein homodimerization activity. Predicted to be involved in G2/M transition of mitotic cell cycle and positive regulation of signal transduction. Predicted to be located in early endosome and perinuclear region of cytoplasm. Predicted to be active in cytoplasm. Is expressed in brain; limb bud; otic capsule; and temporal bone petrous part. Orthologous to human TPD52L1 (TPD52 like 1). [provided by Alliance of Genome Resources, Jul 2025] | 10 | 31208369 | 31321989 | Mouse | 179 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1594796 | Tpd52l1 | TPD52 like 1 | ENCODES a protein that exhibits identical protein binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN G2/M transition of mitotic cell cycle (ortholog); positive regulation of apoptotic signaling pathway (ortholog); positive regulation of JNK cascade (ortholog); ASSOCIATED W ITH Prostatic Neoplasms (ortholog); FOUND IN cytoplasm (ortholog); perinuclear region of cytoplasm (ortholog); INTERACTS WITH (S)-colchicine; 1,3-dinitrobenzene; 17beta-estradiol | 1 | 27991114 | 28109767 | Rat | 166 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 8996910 | Tpd52l1 | TPD52 like 1 | ENCODES a protein that exhibits identical protein binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN G2/M transition of mitotic cell cycle (ortholog); positive regulation of apoptotic signaling pathway (ortholog); positive regulation of JNK cascade (ortholog); ASSOCIATED W ITH Prostatic Neoplasms (ortholog); FOUND IN cytoplasm (ortholog); perinuclear region of cytoplasm (ortholog) | NW_004955436 | 6648140 | 6672474 | Chinchilla | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12049921 | TPD52L1 | TPD52 like 1 | ENCODES a protein that exhibits identical protein binding (inferred); protein homodimerization activity (inferred); INVOLVED IN positive regulation of MAP kinase activity (ortholog); ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN cytoplasm (inferred); perinuclear region of cytoplasm (infer red) | 6 | 122943780 | 123053201 | Bonobo | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12087461 | TPD52L1 | TPD52 like 1 | ENCODES a protein that exhibits identical protein binding (inferred); protein homodimerization activity (inferred); INVOLVED IN positive regulation of MAP kinase activity (ortholog); ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN cytoplasm (inferred); perinuclear region of cytoplasm (infer red) | 1 | 64165833 | 64216851 | Dog | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12593882 | Tpd52l1 | TPD52 like 1 | ENCODES a protein that exhibits identical protein binding (inferred); protein homodimerization activity (inferred); INVOLVED IN positive regulation of MAP kinase activity (ortholog); ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN cytoplasm (inferred); perinuclear region of cytoplasm (infer red) | NW_004936639 | 4153418 | 4244427 | Squirrel | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14285319 | TPD52L1 | TPD52 like 1 | ENCODES a protein that exhibits identical protein binding (inferred); protein homodimerization activity (inferred); INVOLVED IN positive regulation of MAP kinase activity (ortholog); ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN cytoplasm (inferred); perinuclear region of cytoplasm (infer red); INTERACTS WITH deoxynivalenol | | | | Pig | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18907102 | Tpd52l1 | TPD52 like 1 | ENCODES a protein that exhibits identical protein binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN G2/M transition of mitotic cell cycle (ortholog); positive regulation of JNK cascade (ortholog); positive regulation of MAP kinase activity (ortholog); ASSOCIATED WITH Pros tatic Neoplasms (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog) | | | | Naked Mole-Rat | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18452362 | TPD52L1 | TPD52 like 1 | ENCODES a protein that exhibits identical protein binding (inferred); protein homodimerization activity (inferred); INVOLVED IN positive regulation of MAP kinase activity (ortholog); ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN cytoplasm (inferred); perinuclear region of cytoplasm (infer red) | | | | Green Monkey | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155239887 | tpd52l1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625845103 | Tpd52l1 | TPD52 like 1 | ENCODES a protein that exhibits identical protein binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN G2/M transition of mitotic cell cycle (ortholog); positive regulation of apoptotic signaling pathway (ortholog); positive regulation of JNK cascade (ortholog); ASSOCIATED W ITH Prostatic Neoplasms (ortholog); FOUND IN cytoplasm (ortholog); perinuclear region of cytoplasm (ortholog) | | | | Black Rat | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155256243 | tpd52l1.L | | | | | | African Clawed Frog | | symbol | gene, null |
