ENCODES a protein that exhibits DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN inferior colliculus development (ortholog); negative regulation of neuron apoptoti
c process (ortholog); positive regulation of DNA-templated transcription (ortholog); FOUND IN transcription regulator complex (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran
Enables DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within inferior colliculus development; negative regulation of neuron apoptotic process; and positive regula
tion of transcription by RNA polymerase II. Part of transcription regulator complex. Is expressed in several structures, including brain; ganglia; genitourinary system; heart; and retina. Orthologous to human TFAP2D (transcription factor AP-2 delta). [provided by Alliance of Genome Resources, Jul 2025]