| 621005 | Stx3 | syntaxin 3 | ENCODES a protein that exhibits arachidonate binding; SNAP receptor activity; INVOLVED IN membrane fusion; neuron projection development; exocytic insertion of neurotransmitter receptor to postsynaptic membrane (ortholog); ASSOCIATED WITH Bardet-Biedl syndrome 1 (ortholog); Bardet-Biedl syndrome 17 (ortholog); genetic disease (ortholog); FOUND IN growth cone; neuron projection; plasma membrane; INTERACTS WITH 1-benzylpiperazine; 17beta-estradiol; acetamide | 1 | 217940697 | 218114865 | Rat | 237 | symbol , PhenoGen , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 732917 | Stx3 | syntaxin 3 | Predicted to enable SNAP receptor activity; SNARE binding activity; and arachidonate binding activity. Involved in exocytic insertion of neurotransmitter receptor to postsynaptic membrane; modulation of chemical synaptic transmission; and vesicle-mediated transport in synapse. Acts upstream of or wi thin exocytosis and long-term synaptic potentiation. Located in several cellular components, including cytoplasmic vesicle; photoreceptor inner segment; and photoreceptor outer segment. Part of SNARE complex. Is active in Schaffer collateral - CA1 synapse; glutamatergic synapse; and postsynapse. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and respiratory system. Human ortholog(s) of this gene implicated in congenital diarrhea. Orthologous to human STX3 (syntaxin 3). [provided by Alliance of Genome Resources, Jul 2025] | 19 | 11752482 | 11798933 | Mouse | 256 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 735349 | STX3 | syntaxin 3 | The gene is a member of the syntaxin family. The encoded protein is targeted to the apical membrane of epithelial cells where it forms clusters and is important in establishing and maintaining polarity necessary for protein trafficking involving vesicle fusion and exocytosis. Alternative splicing re sults in multiple transcript variants. [provided by RefSeq, May 2010] | 11 | 59754188 | 59805878 | Human | 260 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 8956558 | Stx3 | syntaxin 3 | ENCODES a protein that exhibits arachidonate binding (ortholog); SNAP receptor activity (ortholog); INVOLVED IN exocytic insertion of neurotransmitter receptor to postsynaptic membrane (ortholog); exocytosis (ortholog); long-term synaptic potentiation (ortholog); ASSOCIATED WITH Bardet-Biedl syndrom e 1 (ortholog); Bardet-Biedl syndrome 17 (ortholog); genetic disease (ortholog); FOUND IN apical plasma membrane (ortholog); azurophil granule (ortholog); cell-cell junction (ortholog) | NW_004955511 | 4183210 | 4219528 | Chinchilla | 69 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11699863 | STX3 | syntaxin 3 | ENCODES a protein that exhibits arachidonate binding (ortholog); INVOLVED IN exocytosis (ortholog); long-term synaptic potentiation (ortholog); membrane fusion (ortholog); ASSOCIATED WITH Bardet-Biedl syndrome 1 (ortholog); Bardet-Biedl syndrome 17 (ortholog); genetic disease (ortholog); FOUND IN gr owth cone (ortholog); neuron projection (ortholog); photoreceptor cell terminal bouton (ortholog) | 11 | 54976575 | 55027638 | Bonobo | 86 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12173760 | STX3 | syntaxin 3 | ENCODES a protein that exhibits arachidonate binding (ortholog); INVOLVED IN exocytosis (ortholog); long-term synaptic potentiation (ortholog); membrane fusion (ortholog); ASSOCIATED WITH Bardet-Biedl syndrome 1 (ortholog); Bardet-Biedl syndrome 17 (ortholog); genetic disease (ortholog); FOUND IN ap ical plasma membrane (ortholog); azurophil granule (ortholog); cell-cell junction (ortholog) | 21 | 50298040 | 50322773 | Dog | 80 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12556902 | Stx3 | syntaxin 3 | ENCODES a protein that exhibits arachidonate binding (ortholog); INVOLVED IN exocytosis (ortholog); long-term synaptic potentiation (ortholog); membrane fusion (ortholog); ASSOCIATED WITH Bardet-Biedl syndrome 1 (ortholog); Bardet-Biedl syndrome 17 (ortholog); genetic disease (ortholog); FOUND IN gr owth cone (ortholog); neuron projection (ortholog); photoreceptor cell terminal bouton (ortholog) | NW_004936581 | 2944230 | 2976957 | Squirrel | 86 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13889675 | STX3 | syntaxin 3 | ENCODES a protein that exhibits arachidonate binding (ortholog); INVOLVED IN exocytosis (ortholog); long-term synaptic potentiation (ortholog); membrane fusion (ortholog); ASSOCIATED WITH Bardet-Biedl syndrome 1 (ortholog); Bardet-Biedl syndrome 17 (ortholog); genetic disease (ortholog); FOUND IN gr owth cone (ortholog); neuron projection (ortholog); photoreceptor cell terminal bouton (ortholog) | | | | Pig | 84 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18770973 | STX3 | syntaxin 3 | ENCODES a protein that exhibits arachidonate binding (ortholog); INVOLVED IN exocytosis (ortholog); long-term synaptic potentiation (ortholog); membrane fusion (ortholog); ASSOCIATED WITH Bardet-Biedl syndrome 1 (ortholog); Bardet-Biedl syndrome 17 (ortholog); genetic disease (ortholog); FOUND IN gr owth cone (ortholog); neuron projection (ortholog); photoreceptor cell terminal bouton (ortholog) | | | | Green Monkey | 86 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18916469 | Stx3 | syntaxin 3 | ENCODES a protein that exhibits arachidonate binding (ortholog); INVOLVED IN exocytosis (ortholog); long-term synaptic potentiation (ortholog); membrane fusion (ortholog); ASSOCIATED WITH Bardet-Biedl syndrome 1 (ortholog); Bardet-Biedl syndrome 17 (ortholog); genetic disease (ortholog); FOUND IN ap ical plasma membrane (ortholog); azurophil granule (ortholog); cell-cell junction (ortholog) | | | | Naked Mole-Rat | 83 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626020692 | Stx3 | syntaxin 3 | ENCODES a protein that exhibits arachidonate binding (ortholog); SNAP receptor activity (ortholog); INVOLVED IN exocytic insertion of neurotransmitter receptor to postsynaptic membrane (ortholog); exocytosis (ortholog); long-term synaptic potentiation (ortholog); ASSOCIATED WITH Bardet-Biedl syndrom e 1 (ortholog); Bardet-Biedl syndrome 17 (ortholog); genetic disease (ortholog); FOUND IN apical plasma membrane (ortholog); azurophil granule (ortholog); cell-cell junction (ortholog) | | | | Black Rat | 69 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155255023 | stx3 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155259075 | stx3.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 287755602 | XB5896658 [provisional:stx3] | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 288060597 | XB5896658.L [provisional:stx3] | | | | | | African Clawed Frog | | symbol | gene, null |
| 329329280 | XB5896658.S [provisional:stx3] | | | | | | African Clawed Frog | | symbol | gene, null |