| 1304641 | Stim2 | stromal interaction molecule 2 | ENCODES a protein that exhibits calcium channel regulator activity; calcium ion binding (ortholog); store-operated calcium channel activity (ortholog); INVOLVED IN activation of store-operated calcium channel activity; gene expression (ortholog); intracellular calcium ion homeostasis (ortholog); PAR TICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH Weight Gain (ortholog); FOUND IN endoplasmic reticulum (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cadmium dichloride | 14 | 61091550 | 61217281 | Rat | 104 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1312198 | STIM2 | stromal interaction molecule 2 | This gene is a member of the stromal interaction molecule (STIM) family and likely arose, along with related family member STIM1, from a common ancestral gene. The encoded protein functions to regulate calcium concentrations in the cytosol and endoplasmic reticulum, and is involved in the activation of plasma membrane Orai Ca(2+) entry channels. This gene initiates translation from a non-AUG (UUG) start site. A signal peptide is cleaved from the resulting protein. Multiple transcript variants result from alternative splicing. [provided by RefSeq, Dec 2009] | 4 | 26860841 | 27025381 | Human | 102 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1312199 | Stim2 | stromal interaction molecule 2 | Predicted to enable calcium channel regulator activity; calcium ion binding activity; and store-operated calcium channel activity. Predicted to be involved in activation of store-operated calcium channel activity; intracellular calcium ion homeostasis; and store-operated calcium entry. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum and plasma membrane. Is expressed in several structures, including adipose tissue; cardiovascular system; central nervous system; endocrine gland; and male reproductive gland or organ. Orthologous to human STIM2 (stromal interaction molecule 2). [provided by Alliance of Genome Resources, Apr 2025] | 5 | 54155865 | 54278399 | Mouse | 165 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8929889 | Stim2 | stromal interaction molecule 2 | ENCODES a protein that exhibits calcium channel regulator activity (ortholog); calcium ion binding (ortholog); store-operated calcium channel activity (ortholog); INVOLVED IN activation of store-operated calcium channel activity (ortholog); gene expression (ortholog); intracellular calcium ion homeo stasis (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH Weight Gain (ortholog); FOUND IN endoplasmic reticulum (ortholog); plasma membrane (ortholog) | NW_004955443 | 18281245 | 18424750 | Chinchilla | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11800185 | STIM2 | stromal interaction molecule 2 | ENCODES a protein that exhibits calcium channel regulator activity (ortholog); INVOLVED IN activation of store-operated calcium channel activity (ortholog); gene expression (ortholog); protein catabolic process (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH Weight Gain (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); plasma membrane (inferred) | 4 | 21262272 | 21424944 | Bonobo | 37 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12107905 | STIM2 | stromal interaction molecule 2 | ENCODES a protein that exhibits calcium channel regulator activity (ortholog); INVOLVED IN activation of store-operated calcium channel activity (ortholog); gene expression (ortholog); protein catabolic process (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH Weight Gain (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); plasma membrane (inferred) | 3 | 83560690 | 83703978 | Dog | 36 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12563270 | Stim2 | stromal interaction molecule 2 | ENCODES a protein that exhibits calcium channel regulator activity (ortholog); INVOLVED IN activation of store-operated calcium channel activity (ortholog); gene expression (ortholog); protein catabolic process (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH Weight Gain (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); plasma membrane (inferred) | NW_004936477 | 2824720 | 2950069 | Squirrel | 36 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155257372 | stim2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18931551 | Stim2 | stromal interaction molecule 2 | ENCODES a protein that exhibits calcium channel regulator activity (ortholog); store-operated calcium channel activity (ortholog); INVOLVED IN activation of store-operated calcium channel activity (ortholog); gene expression (ortholog); positive regulation of calcium ion transport (ortholog); PARTIC IPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH Weight Gain (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); plasma membrane (inferred) | | | | Naked Mole-Rat | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18377811 | STIM2 | stromal interaction molecule 2 | ENCODES a protein that exhibits calcium channel regulator activity (ortholog); INVOLVED IN activation of store-operated calcium channel activity (ortholog); gene expression (ortholog); protein catabolic process (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH Weight Gain (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); plasma membrane (inferred) | | | | Green Monkey | 35 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14133580 | STIM2 | stromal interaction molecule 2 | ENCODES a protein that exhibits calcium channel regulator activity (ortholog); INVOLVED IN activation of store-operated calcium channel activity (ortholog); gene expression (ortholog); protein catabolic process (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH Weight Gain (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); membrane (inferred) | | | | Pig | 37 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 625903021 | Stim2 | stromal interaction molecule 2 | ENCODES a protein that exhibits calcium channel regulator activity (ortholog); calcium ion binding (ortholog); store-operated calcium channel activity (ortholog); INVOLVED IN activation of store-operated calcium channel activity (ortholog); gene expression (ortholog); intracellular calcium ion homeo stasis (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH Weight Gain (ortholog); FOUND IN endoplasmic reticulum (ortholog); plasma membrane (ortholog) | | | | Black Rat | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 405858519 | stim2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405858187 | stim2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 626175154 | stim2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405864354 | stim2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405860565 | stim2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155255582 | stim2.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 13825087 | STIM2-AS1 | STIM2 antisense RNA 1 | | 4 | 26859624 | 26860599 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |