| 1348930 | SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | The protein encoded by this gene is a GTPase activator, working with the GTPase CDC42 to negatively regulate neuronal migration. The encoded protein interacts with the transmembrane receptor ROBO1 to inactivate CDC42. [provided by RefSeq, Sep 2016] | 12 | 63844700 | 64162217 | Human | 128 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1557733 | Srgap1 | SLIT-ROBO Rho GTPase activating protein 1 | Enables GTPase activator activity and small GTPase binding activity. Acts upstream of or within Rho protein signal transduction and cell migration. Predicted to be active in cytoplasm. Is expressed in mesonephros mesenchyme; metanephros; nervous system; neural retina; and vomeronasal organ. Used to study focal segmental glomerulosclerosis. Human ortholog(s) of this gene implicated in papillary thyroid carcinoma. Orthologous to human SRGAP1 (SLIT-ROBO Rho GTPase activating protein 1). [provided by Alliance of Genome Resources, Apr 2025] | 10 | 121616896 | 121883740 | Mouse | 118 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1566260 | Srgap1 | SLIT-ROBO Rho GTPase activating protein 1 | ENCODES a protein that exhibits GTPase activator activity (ortholog); small GTPase binding (ortholog); INVOLVED IN cell migration (ortholog); Rho protein signal transduction (ortholog); ASSOCIATED WITH Brain Hypoxia-Ischemia; basal cell carcinoma (ortholog); CAKUT (ortholog); INTERACTS WITH 17alpha- ethynylestradiol; 17beta-estradiol; 2,3,7,8-Tetrachlorodibenzofuran | 7 | 59215007 | 59479600 | Rat | 108 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 8814575 | Srgap1 | SLIT-ROBO Rho GTPase activating protein 1 | ENCODES a protein that exhibits GTPase activator activity (ortholog); small GTPase binding (ortholog); INVOLVED IN cell migration (ortholog); Rho protein signal transduction (ortholog); ASSOCIATED WITH basal cell carcinoma (ortholog); Brain Hypoxia-Ischemia (ortholog); CAKUT (ortholog) | NW_004955458 | 10842745 | 10991500 | Chinchilla | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11733231 | SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | ENCODES a protein that exhibits GTPase activator activity (inferred); small GTPase binding (inferred); INVOLVED IN cell migration (ortholog); Rho protein signal transduction (ortholog); ASSOCIATED WITH basal cell carcinoma (ortholog); Brain Hypoxia-Ischemia (ortholog); CAKUT (ortholog) | 12 | 24760093 | 25066794 | Bonobo | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12067958 | SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | ENCODES a protein that exhibits GTPase activator activity (inferred); small GTPase binding (inferred); INVOLVED IN cell migration (ortholog); Rho protein signal transduction (ortholog); ASSOCIATED WITH basal cell carcinoma (ortholog); Brain Hypoxia-Ischemia (ortholog); CAKUT (ortholog) | 10 | 6677409 | 6947495 | Dog | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12654425 | Srgap1 | SLIT-ROBO Rho GTPase activating protein 1 | ENCODES a protein that exhibits GTPase activator activity (inferred); small GTPase binding (inferred); INVOLVED IN cell migration (ortholog); Rho protein signal transduction (ortholog); ASSOCIATED WITH basal cell carcinoma (ortholog); Brain Hypoxia-Ischemia (ortholog); CAKUT (ortholog) | NW_004936545 | 2277449 | 2557330 | Squirrel | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155257536 | srgap1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14213201 | SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | ENCODES a protein that exhibits GTPase activator activity (inferred); small GTPase binding (inferred); INVOLVED IN cell migration (ortholog); Rho protein signal transduction (ortholog); ASSOCIATED WITH basal cell carcinoma (ortholog); Brain Hypoxia-Ischemia (ortholog); CAKUT (ortholog); INTERACTS WI TH deoxynivalenol | | | | Pig | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18481456 | SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | ENCODES a protein that exhibits GTPase activator activity (inferred); small GTPase binding (inferred); INVOLVED IN cell migration (ortholog); Rho protein signal transduction (ortholog); ASSOCIATED WITH basal cell carcinoma (ortholog); Brain Hypoxia-Ischemia (ortholog); CAKUT (ortholog) | | | | Green Monkey | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18928758 | Srgap1 | SLIT-ROBO Rho GTPase activating protein 1 | ENCODES a protein that exhibits GTPase activator activity (inferred); small GTPase binding (inferred); INVOLVED IN cell migration (ortholog); Rho protein signal transduction (ortholog); ASSOCIATED WITH basal cell carcinoma (ortholog); Brain Hypoxia-Ischemia (ortholog); CAKUT (ortholog) | | | | Naked Mole-Rat | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626050714 | Srgap1 | SLIT-ROBO Rho GTPase activating protein 1 | ENCODES a protein that exhibits GTPase activator activity (ortholog); small GTPase binding (ortholog); INVOLVED IN cell migration (ortholog); Rho protein signal transduction (ortholog); ASSOCIATED WITH basal cell carcinoma (ortholog); Brain Hypoxia-Ischemia (ortholog); CAKUT (ortholog) | | | | Black Rat | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 405863869 | srgap1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405856924 | srgap1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 628359329 | srgap1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405861028 | srgap1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 628359443 | srgap1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405861711 | srgap1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405862829 | srgap1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405856082 | srgap1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405858036 | srgap1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 626468922 | srgap1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405858312 | srgap1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 16572697 | AC025576.3 | novel transcript, antisense to SRGAP1 | | | | | Human | | name | gene, lncrna |