| 1311253 | Spcs2 | signal peptidase complex subunit 2 | ENCODES a protein that exhibits peptidase activity (inferred); INVOLVED IN signal peptide processing (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); signal peptidase complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; bisphenol A | 1 | 163575842 | 163595269 | Rat | 107 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1345346 | SPCS2 | signal peptidase complex subunit 2 | Predicted to enable peptidase activity. Involved in signal peptide processing. Located in endoplasmic reticulum membrane. Part of signal peptidase complex. [provided by Alliance of Genome Resources, Jul 2025] | 11 | 74949266 | 74979033 | Human | 105 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1553144 | Spcs2 | signal peptidase complex subunit 2 homolog (S. cerevisiae) | Predicted to be involved in protein targeting to ER and signal peptide processing. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of signal peptidase complex. Is expressed in several structures, including alimentary system; brain; integumental system; respiratory sys tem; and urinary system. Orthologous to human SPCS2 (signal peptidase complex subunit 2). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 99486775 | 99512576 | Mouse | 103 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8989048 | Spcs2 | signal peptidase complex subunit 2 | INVOLVED IN signal peptide processing (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); signal peptidase complex (ortholog) | NW_004955414 | 16807986 | 16825013 | Chinchilla | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11749220 | SPCS2 | signal peptidase complex subunit 2 | ENCODES a protein that exhibits peptidase activity (inferred); INVOLVED IN protein targeting to ER (inferred); signal peptide processing (inferred); FOUND IN endoplasmic reticulum membrane (inferred); membrane (inferred); signal peptidase complex (inferred) | 11 | 70013810 | 70042618 | Bonobo | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12238582 | SPCS2 | signal peptidase complex subunit 2 | ENCODES a protein that exhibits peptidase activity (inferred); INVOLVED IN signal peptide processing (inferred); FOUND IN signal peptidase complex | 21 | 23485367 | 23510249 | Dog | 15 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 12512884 | Spcs2 | signal peptidase complex subunit 2 | ENCODES a protein that exhibits peptidase activity (inferred); INVOLVED IN protein targeting to ER (inferred); signal peptide processing (inferred); FOUND IN endoplasmic reticulum membrane (inferred); membrane (inferred); signal peptidase complex (inferred) | NW_004936498 | 3848045 | 3872691 | Squirrel | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14116083 | SPCS2 | signal peptidase complex subunit 2 | ENCODES a protein that exhibits peptidase activity (inferred); INVOLVED IN signal peptide processing (inferred); FOUND IN endoplasmic reticulum membrane (inferred); membrane (inferred); signal peptidase complex (inferred) | | | | Pig | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155235156 | spcs2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18919375 | Spcs2 | signal peptidase complex subunit 2 | ENCODES a protein that exhibits peptidase activity (inferred); INVOLVED IN protein targeting to ER (inferred); signal peptide processing (inferred); FOUND IN endoplasmic reticulum membrane (inferred); membrane (inferred); signal peptidase complex (inferred) | | | | Naked Mole-Rat | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625900670 | Spcs2 | signal peptidase complex subunit 2 | INVOLVED IN signal peptide processing (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); signal peptidase complex (ortholog) | | | | Black Rat | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18633646 | SPCS2 | signal peptidase complex subunit 2 | ENCODES a protein that exhibits peptidase activity (inferred); INVOLVED IN protein targeting to ER (inferred); signal peptide processing (inferred); FOUND IN endoplasmic reticulum membrane (inferred); membrane (inferred); signal peptidase complex (inferred) | | | | Green Monkey | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155239118 | spcs2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155252463 | spcs2.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 2294507 | Spcs2-ps | signal peptidase complex subunit 2, pseudogene | INTERACTS WITH paracetamol | 2 | 129220088 | 129221316 | Mouse | 2 | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 2323226 | Spcs2-ps1 | signal peptidase complex subunit 2, pseudogene 1 | | 5 | 112029464 | 112030217 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 1342746 | SPCS2P1 | signal peptidase complex subunit 2 pseudogene 1 | | 15 | 43130991 | 43131685 | Human | | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, pseudo, INFERRED [RefSeq] |
| 7241987 | SPCS2P2 | signal peptidase complex subunit 2 pseudogene 2 | | 10 | 100143612 | 100144005 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 7241954 | SPCS2P3 | signal peptidase complex subunit 2 pseudogene 3 | | 5 | 816327 | 817291 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 7241942 | SPCS2P4 | signal peptidase complex subunit 2 pseudogene 4 | INTERACTS WITH benzo[a]pyrene; lead diacetate; sodium arsenite | 1 | 28095035 | 28096442 | Human | 6 | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |