Enables ubiquitin protein ligase activity. Involved in positive regulation of JNK cascade and protein autoubiquitination. [provided by Alliance of Genome Resources, Jul 2025]
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in positive regulation of JNK cascade; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; and protein autoubiquitination. Is expressed in several structures, including central nervous syste
m; lung; metanephros; retina; and vibrissa. Orthologous to human SH3RF3 (SH3 domain containing ring finger 3). [provided by Alliance of Genome Resources, Jul 2025]
ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN positive regulation of JNK cascade (ortholog); protein autoubiquitination (ortholog); ASSOCIATED WITH amphetamine abuse (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodiox
ENCODES a protein that exhibits metal ion binding (inferred); transferase activity (inferred); ubiquitin protein ligase activity (inferred); INVOLVED IN positive regulation of JNK cascade (inferred); protein autoubiquitination (inferred); protein ubiquitination (inferred); ASSOCIATED WITH amphetamin