| 1346308 | SGIP1 | SH3GL interacting endocytic adaptor 1 | SGIP1 functions as an endocytic protein that affects signaling by receptors in neuronal systems involved in energy homeostasis via its interaction with endophilins (see SH3GL3; MIM 603362) (Trevaskis et al., 2005 [PubMed 15919751] and Uezu et al., 2007 [PubMed 1 7626015]).[supplied by OMIM, Mar 2008] | 1 | 66533361 | 66751139 | Human | 84 | symbol , COSMIC , description , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1564957 | Sgip1 | SH3GL interacting endocytic adaptor 1 | ENCODES a protein that exhibits tubulin binding; microtubule binding (ortholog); phospholipid binding (ortholog); INVOLVED IN energy homeostasis; positive regulation of eating behavior; positive regulation of feeding behavior; ASSOCIATED WITH intellectual disability (ortholog); FOUND IN presynapse; AP-2 adaptor complex (ortholog); clathrin-coated pit (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 5 | 122755216 | 122963677 | Rat | 88 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1622259 | Sgip1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | Enables microtubule binding activity and phospholipid binding activity. Involved in positive regulation of receptor-mediated endocytosis and synaptic vesicle endocytosis. Located in clathrin-coated vesicle and plasma membrane. Part of AP-2 adaptor complex. Is active in presynapse. Is expressed in ce ntral nervous system; genitourinary system; and small intestine. Orthologous to human SGIP1 (SH3GL interacting endocytic adaptor 1). [provided by Alliance of Genome Resources, Jul 2025] | 4 | 102616351 | 102834623 | Mouse | 101 | symbol , PhenoGen , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 8905245 | Sgip1 | SH3GL interacting endocytic adaptor 1 | ENCODES a protein that exhibits microtubule binding (ortholog); phospholipid binding (ortholog); SH3 domain binding (ortholog); INVOLVED IN energy homeostasis (ortholog); plasma membrane tubulation (ortholog); positive regulation of eating behavior (ortholog); ASSOCIATED WITH intellectual disability (ortholog); FOUND IN AP-2 adaptor complex (ortholog); clathrin-coated pit (ortholog); clathrin-coated vesicle (ortholog) | NW_004955423 | 24155401 | 24353166 | Chinchilla | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11933206 | SGIP1 | SH3GL interacting endocytic adaptor 1 | ENCODES a protein that exhibits microtubule binding (inferred); phospholipid binding (inferred); SH3 domain binding (inferred); INVOLVED IN energy homeostasis (ortholog); plasma membrane tubulation (ortholog); positive regulation of eating behavior (ortholog); ASSOCIATED WITH intellectual disability (ortholog); FOUND IN AP-2 adaptor complex (inferred); clathrin-coated pit (inferred); clathrin-coated vesicle (inferred) | 1 | 65782856 | 65999721 | Bonobo | 41 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12111302 | SGIP1 | SH3GL interacting endocytic adaptor 1 | ENCODES a protein that exhibits microtubule binding (inferred); phospholipid binding (inferred); SH3 domain binding (inferred); INVOLVED IN energy homeostasis (ortholog); plasma membrane tubulation (ortholog); positive regulation of eating behavior (ortholog); ASSOCIATED WITH intellectual disability (ortholog); FOUND IN AP-2 adaptor complex (inferred); clathrin-coated pit (inferred); clathrin-coated vesicle (inferred) | 5 | 43741507 | 43944289 | Dog | 33 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12687020 | Sgip1 | SH3GL interacting endocytic adaptor 1 | ENCODES a protein that exhibits microtubule binding (inferred); phospholipid binding (inferred); SH3 domain binding (inferred); INVOLVED IN energy homeostasis (ortholog); plasma membrane tubulation (ortholog); positive regulation of eating behavior (ortholog); ASSOCIATED WITH intellectual disability (ortholog); FOUND IN AP-2 adaptor complex (inferred); clathrin-coated pit (inferred); clathrin-coated vesicle (inferred) | NW_004936591 | 4815222 | 5015250 | Squirrel | 41 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18926211 | Sgip1 | SH3GL interacting endocytic adaptor 1 | ENCODES a protein that exhibits microtubule binding (ortholog); phospholipid binding (ortholog); SH3 domain binding (ortholog); INVOLVED IN energy homeostasis (ortholog); plasma membrane tubulation (ortholog); positive regulation of eating behavior (ortholog); ASSOCIATED WITH intellectual disability (ortholog); FOUND IN AP-2 adaptor complex (ortholog); presynapse (ortholog) | | | | Naked Mole-Rat | 38 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626092630 | Sgip1 | SH3GL interacting endocytic adaptor 1 | ENCODES a protein that exhibits microtubule binding (ortholog); phospholipid binding (ortholog); SH3 domain binding (ortholog); INVOLVED IN energy homeostasis (ortholog); plasma membrane tubulation (ortholog); positive regulation of eating behavior (ortholog); ASSOCIATED WITH intellectual disability (ortholog); FOUND IN AP-2 adaptor complex (ortholog); clathrin-coated pit (ortholog); clathrin-coated vesicle (ortholog) | | | | Black Rat | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155250365 | sgip1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18723249 | SGIP1 | SH3GL interacting endocytic adaptor 1 | ENCODES a protein that exhibits microtubule binding (inferred); phospholipid binding (inferred); SH3 domain binding (inferred); INVOLVED IN energy homeostasis (ortholog); plasma membrane tubulation (ortholog); positive regulation of eating behavior (ortholog); ASSOCIATED WITH intellectual disability (ortholog); FOUND IN AP-2 adaptor complex (inferred); clathrin-coated pit (inferred); clathrin-coated vesicle (inferred) | | | | Green Monkey | 40 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14135042 | SGIP1 | SH3GL interacting endocytic adaptor 1 | ENCODES a protein that exhibits microtubule binding (ortholog); phospholipid binding (ortholog); tubulin binding (ortholog); INVOLVED IN energy homeostasis (ortholog); plasma membrane tubulation (ortholog); positive regulation of eating behavior (ortholog); ASSOCIATED WITH intellectual disability (o rtholog); FOUND IN AP-2 adaptor complex (ortholog); clathrin-coated vesicle (ortholog); presynapse (ortholog) | | | | Pig | 35 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155254791 | sgip1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155253820 | sgip1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 16558152 | AL139147.1 | novel transcript, antisense to SGIP1 | | | | | Human | | name | gene, lncrna |