Selt Gene Search Result

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10 records found for search term Selt

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
14387279	SelT						Fly		symbol	gene, null
14387278	selt-1.1						Roundworm		symbol	gene, null
14387281	selt-1.2						Roundworm		symbol	gene, null
1359128	Selenot	selenoprotein T	ENCODES a protein that exhibits thioredoxin-disulfide reductase (NADPH) activity; INVOLVED IN cellular oxidant detoxification; positive regulation of cytosolic calcium ion concentration; positive regulation of growth hormone secretion; FOUND IN endoplasmic reticulum membrane; endoplasmic reticulum ( ... (more) ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 6-propyl-2-thiouracil; amitrole	2	144954324	144971375	Rat	81	old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]
1553437	Selenot	selenoprotein T	This gene encodes a selenoprotein, containing a selenocysteine (Sec) residue at the active site. Sec is encoded by the UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, that ... (more) is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein is localized in the endoplasmic reticulum. It belongs to the SelWTH family that possesses a thioredoxin-like fold and a conserved CxxU (C is cysteine, U is Sec) motif found in several redox active proteins. Studies in mice indicate a crucial role for this gene in the protection of dopaminergic neurons against oxidative stress in Parkinson's disease, and in the control of glucose homeostasis in pancreatic beta-cells. A pseudogene of this locus has been identified on chromosome 8. [provided by RefSeq, Aug 2017]	3	58484057	58500965	Mouse	100	old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]
1602000	SELENOT	selenoprotein T	This gene encodes a selenoprotein, containing a selenocysteine (Sec) residue at the active site. Sec is encoded by the UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, that ... (more) is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein is localized in the endoplasmic reticulum. It belongs to the SelWTH family that possesses a thioredoxin-like fold and a conserved CxxU (C is cysteine, U is Sec) motif found in several redox active proteins. Studies in mice indicate a crucial role for this gene in the protection of dopaminergic neurons against oxidative stress in Parkinson's disease, and in the control of glucose homeostasis in pancreatic beta-cells. Pseudogenes of this locus have been identified on chromosomes 9 and 5. [provided by RefSeq, Sep 2017]	3	150603321	150630436	Human	84	old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]
12123879	SELENOT	selenoprotein T	ENCODES a protein that exhibits oxidoreductase activity (inferred); thioredoxin-disulfide reductase (NADPH) activity (inferred); INVOLVED IN glucose homeostasis (ortholog); insulin secretion involved in cellular response to glucose stimulus (ortholog); pancreas development (ortholog); FOUND IN endop ... (more) lasmic reticulum (inferred); endoplasmic reticulum membrane (inferred)	23	45247088	45271229	Dog	16	old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]
14276735	SELENOT	selenoprotein T	ENCODES a protein that exhibits thioredoxin-disulfide reductase (NADPH) activity (ortholog); INVOLVED IN cell redox homeostasis (ortholog); cellular oxidant detoxification (ortholog); glucose homeostasis (ortholog); FOUND IN endoplasmic reticulum (ortholog)				Pig	16	old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]
18416356	SELENOT	selenoprotein T	ENCODES a protein that exhibits thioredoxin-disulfide reductase (NADPH) activity (ortholog); INVOLVED IN cell redox homeostasis (ortholog); cellular oxidant detoxification (ortholog); glucose homeostasis (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog)				Green Monkey	13	old_gene_symbol	gene, protein-coding, MODEL [RefSeq]
18908627	Selenot	selenoprotein T	ENCODES a protein that exhibits oxidoreductase activity (inferred); thioredoxin-disulfide reductase (NADPH) activity (inferred); INVOLVED IN glucose homeostasis (ortholog); insulin secretion involved in cellular response to glucose stimulus (ortholog); pancreas development (ortholog); FOUND IN endop ... (more) lasmic reticulum (ortholog)				Naked Mole-Rat	15	old_gene_symbol	gene, protein-coding, MODEL [RefSeq]