| 1588939 | Ric3 | RIC3 acetylcholine receptor chaperone | ENCODES a protein that exhibits acetylcholine receptor binding; protein folding chaperone (ortholog); INVOLVED IN positive regulation of cytosolic calcium ion concentration; synaptic transmission, cholinergic; positive regulation of protein localization to cell surface (ortholog); FOUND IN endoplasm ic reticulum (ortholog); membrane (ortholog); INTERACTS WITH bisphenol A; indole-3-methanol; N-nitrosodiethylamine | 1 | 172465638 | 172521349 | Rat | 55 | symbol , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1606245 | RIC3 | RIC3 acetylcholine receptor chaperone | This gene encodes a member of the resistance to inhibitors of cholinesterase 3-like family which functions as a chaperone of specific 5-hydroxytryptamine type 3 receptor and nicotinic acetylcholine receptor subtypes. The encoded protein influences the folding and assembly of these receptor subunits in the endoplasmic reticulum and expression on the cell surface. This protein contains an N-terminal transmembrane domain, a proline-rich spacer, and a cytosolic C-terminal coiled-coil domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016] | 11 | 8092965 | 8169025 | Human | 52 | symbol , COSMIC , name , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1619704 | Ric3 | RIC3 acetylcholine receptor chaperone | Enables protein folding chaperone. Acts upstream of or within protein-containing complex assembly. Located in endoplasmic reticulum and membrane. Orthologous to human RIC3 (RIC3 acetylcholine receptor chaperone). [provided b y Alliance of Genome Resources, Jul 2025] | 7 | 108633475 | 108682538 | Mouse | 54 | symbol , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8883181 | Ric3 | RIC3 acetylcholine receptor chaperone | ENCODES a protein that exhibits acetylcholine receptor binding (ortholog); protein folding chaperone (ortholog); INVOLVED IN positive regulation of cytosolic calcium ion concentration (ortholog); positive regulation of protein localization to cell surface (ortholog); protein-containing complex assem bly (ortholog); FOUND IN endoplasmic reticulum (ortholog); membrane (ortholog) | NW_004955414 | 23925149 | 23967772 | Chinchilla | 10 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 11919661 | RIC3 | RIC3 acetylcholine receptor chaperone | ENCODES a protein that exhibits acetylcholine receptor binding (ortholog); INVOLVED IN positive regulation of cytosolic calcium ion concentration (ortholog); protein-containing complex assembly (ortholog); synaptic transmission, cholinergic (ortholog); FOUND IN endoplasmic reticulum (inferred); endo plasmic reticulum membrane (inferred); membrane (inferred) | 11 | 8210061 | 8287211 | Bonobo | 17 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 12278526 | RIC3 | RIC3 acetylcholine receptor chaperone | ENCODES a protein that exhibits acetylcholine receptor binding (ortholog); INVOLVED IN positive regulation of cytosolic calcium ion concentration (ortholog); protein-containing complex assembly (ortholog); synaptic transmission, cholinergic (ortholog); FOUND IN endoplasmic reticulum (inferred); endo plasmic reticulum membrane (inferred); membrane (inferred) | 21 | 31629824 | 31681832 | Dog | 17 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 12727082 | Ric3 | RIC3 acetylcholine receptor chaperone | ENCODES a protein that exhibits acetylcholine receptor binding (ortholog); INVOLVED IN positive regulation of cytosolic calcium ion concentration (ortholog); protein-containing complex assembly (ortholog); synaptic transmission, cholinergic (ortholog); FOUND IN endoplasmic reticulum (inferred); endo plasmic reticulum membrane (inferred); membrane (inferred) | NW_004936528 | 9790594 | 9829120 | Squirrel | 17 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 14081816 | RIC3 | RIC3 acetylcholine receptor chaperone | ENCODES a protein that exhibits acetylcholine receptor binding (ortholog); INVOLVED IN positive regulation of cytosolic calcium ion concentration (ortholog); protein-containing complex assembly (ortholog); synaptic transmission, cholinergic (ortholog); FOUND IN endoplasmic reticulum (inferred); endo plasmic reticulum membrane (inferred); membrane (inferred) | | | | Pig | 17 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 18911436 | Ric3 | RIC3 acetylcholine receptor chaperone | ENCODES a protein that exhibits acetylcholine receptor binding (ortholog); protein folding chaperone (ortholog); INVOLVED IN positive regulation of cytosolic calcium ion concentration (ortholog); positive regulation of protein localization to cell surface (ortholog); protein-containing complex assem bly (ortholog); FOUND IN endoplasmic reticulum (ortholog); membrane (ortholog) | | | | Naked Mole-Rat | 16 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 18453544 | RIC3 | RIC3 acetylcholine receptor chaperone | ENCODES a protein that exhibits acetylcholine receptor binding (ortholog); INVOLVED IN positive regulation of cytosolic calcium ion concentration (ortholog); protein-containing complex assembly (ortholog); synaptic transmission, cholinergic (ortholog); FOUND IN endoplasmic reticulum (inferred); endo plasmic reticulum membrane (inferred); membrane (inferred) | | | | Green Monkey | 17 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 625906504 | Ric3 | RIC3 acetylcholine receptor chaperone | ENCODES a protein that exhibits acetylcholine receptor binding (ortholog); protein folding chaperone (ortholog); INVOLVED IN positive regulation of cytosolic calcium ion concentration (ortholog); positive regulation of protein localization to cell surface (ortholog); protein-containing complex assem bly (ortholog); FOUND IN endoplasmic reticulum (ortholog); membrane (ortholog) | | | | Black Rat | 10 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 155231766 | ric3 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155231765 | ric3.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155240031 | ric3.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 14392839 | RIC3-DT | RIC3 divergent transcript | | 11 | 8169070 | 8180247 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
