| 1306428 | Polr3f | RNA polymerase III subunit F | ENCODES a protein that exhibits 4 iron, 4 sulfur cluster binding (ortholog); double-stranded DNA binding (ortholog); INVOLVED IN positive regulation of innate immune response (ortholog); positive regulation of interferon-beta production (ortholog); termination of RNA polymerase III transcription (or tholog); PARTICIPATES IN RNA polymerase III transcription pathway; purine metabolic pathway; pyrimidine metabolic pathway; ASSOCIATED WITH immunodeficiency 101 (ortholog); FOUND IN RNA polymerase III complex (ortholog); INTERACTS WITH amitrole; bisphenol A; cyclosporin A | 3 | 152361798 | 152378169 | Rat | 89 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1315038 | POLR3F | RNA polymerase III subunit F | The protein encoded by this gene is one of more than a dozen subunits forming eukaryotic RNA polymerase III (RNA Pol III), which transcribes 5S ribosomal RNA and tRNA genes. This protein has been shown to bind both TFIIIB90 and TBP, two subunits of RNA polymerase III transcription initiation factor IIIB (TFIIIB). Unlike most of the other RNA Pol III subunits, the encoded protein is unique to this polymerase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] | 20 | 18467390 | 18484646 | Human | 102 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1552445 | Polr3f | polymerase (RNA) III (DNA directed) polypeptide F | Predicted to enable 4 iron, 4 sulfur cluster binding activity and double-stranded DNA binding activity. Predicted to be involved in positive regulation of innate immune response and positive regulation of interferon-beta production. Predicted to be part of RNA polymerase III complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and respiratory system. Human ortholog(s) of this gene implicated in immunodeficiency 101. Orthologous to human POLR3F (RNA polymerase III subunit F). [provided by Alliance of Genome Resources, Apr 2025] | 2 | 144369665 | 144383699 | Mouse | 101 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 9067021 | Polr3f | RNA polymerase III subunit F | ENCODES a protein that exhibits 4 iron, 4 sulfur cluster binding (ortholog); double-stranded DNA binding (ortholog); INVOLVED IN positive regulation of innate immune response (ortholog); positive regulation of interferon-beta production (ortholog); termination of RNA polymerase III transcription (or tholog); PARTICIPATES IN RNA polymerase III transcription pathway; ASSOCIATED WITH immunodeficiency 101 (ortholog); FOUND IN RNA polymerase III complex (ortholog) | NW_004955415 | 27022081 | 27036475 | Chinchilla | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11917546 | POLR3F | RNA polymerase III subunit F | ENCODES a protein that exhibits 4 iron, 4 sulfur cluster binding (inferred); double-stranded DNA binding (inferred); INVOLVED IN positive regulation of innate immune response (inferred); positive regulation of interferon-beta production (inferred); termination of RNA polymerase III transcription (in ferred); PARTICIPATES IN RNA polymerase III transcription pathway; ASSOCIATED WITH immunodeficiency 101 (ortholog); FOUND IN cytoplasm (inferred); DNA-directed RNA polymerase complex (inferred); nucleoplasm (inferred) | 20 | 18429402 | 18447634 | Bonobo | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12054275 | POLR3F | RNA polymerase III subunit F | ENCODES a protein that exhibits 4 iron, 4 sulfur cluster binding (inferred); double-stranded DNA binding (inferred); metal ion binding (inferred); INVOLVED IN COPII-coated vesicle budding (inferred); endoplasmic reticulum to Golgi vesicle-mediated transport (inferred); intracellular protein transpor t (inferred); PARTICIPATES IN RNA polymerase III transcription pathway; ASSOCIATED WITH immunodeficiency 101 (ortholog); FOUND IN COPII vesicle coat (inferred); cytoplasm (inferred); cytoplasmic vesicle (inferred) | 24 | 4715146 | 4727938 | Dog | 42 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12695989 | Polr3f | RNA polymerase III subunit F | ENCODES a protein that exhibits 4 iron, 4 sulfur cluster binding (inferred); double-stranded DNA binding (inferred); INVOLVED IN positive regulation of innate immune response (inferred); positive regulation of interferon-beta production (inferred); termination of RNA polymerase III transcription (in ferred); PARTICIPATES IN RNA polymerase III transcription pathway; ASSOCIATED WITH immunodeficiency 101 (ortholog); FOUND IN cytoplasm (inferred); DNA-directed RNA polymerase complex (inferred); nucleoplasm (inferred) | NW_004936485 | 1796857 | 1814186 | Squirrel | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14023361 | POLR3F | RNA polymerase III subunit F | ENCODES a protein that exhibits 4 iron, 4 sulfur cluster binding (inferred); double-stranded DNA binding (inferred); INVOLVED IN positive regulation of innate immune response (inferred); positive regulation of interferon-beta production (inferred); termination of RNA polymerase III transcription (in ferred); PARTICIPATES IN RNA polymerase III transcription pathway; ASSOCIATED WITH immunodeficiency 101 (ortholog); FOUND IN cytoplasm (inferred); DNA-directed RNA polymerase complex (inferred); nucleoplasm (inferred) | | | | Pig | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18396012 | POLR3F | RNA polymerase III subunit F | ENCODES a protein that exhibits 4 iron, 4 sulfur cluster binding (inferred); double-stranded DNA binding (inferred); INVOLVED IN positive regulation of innate immune response (inferred); positive regulation of interferon-beta production (inferred); termination of RNA polymerase III transcription (in ferred); PARTICIPATES IN RNA polymerase III transcription pathway; ASSOCIATED WITH immunodeficiency 101 (ortholog); FOUND IN cytoplasm (inferred); DNA-directed RNA polymerase complex (inferred); nucleoplasm (inferred) | | | | Green Monkey | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626042669 | Polr3f | RNA polymerase III subunit F | ENCODES a protein that exhibits 4 iron, 4 sulfur cluster binding (ortholog); double-stranded DNA binding (ortholog); INVOLVED IN positive regulation of innate immune response (ortholog); positive regulation of interferon-beta production (ortholog); termination of RNA polymerase III transcription (or tholog); PARTICIPATES IN RNA polymerase III transcription pathway; ASSOCIATED WITH immunodeficiency 101 (ortholog); FOUND IN RNA polymerase III complex (ortholog) | | | | Black Rat | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155233998 | polr3f | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18921721 | Polr3f | RNA polymerase III subunit F | ENCODES a protein that exhibits 4 iron, 4 sulfur cluster binding (ortholog); double-stranded DNA binding (ortholog); INVOLVED IN positive regulation of innate immune response (ortholog); positive regulation of interferon-beta production (ortholog); termination of RNA polymerase III transcription (or tholog); PARTICIPATES IN RNA polymerase III transcription pathway; ASSOCIATED WITH immunodeficiency 101 (ortholog); FOUND IN cytoplasm (inferred); DNA-directed RNA polymerase complex (inferred); nucleoplasm (inferred) | | | | Naked Mole-Rat | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155255401 | polr3f.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 2319371 | Polr3f-ps1 | RNA polymerase III subunit F, pseudogene 1 | | 14 | 73451223 | 73454756 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 41004689 | Polr3f-ps2 | RNA polymerase III subunit F, pseudogene 2 | | 14 | 69539211 | 69564430 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
