| 621021 | Pkia | cAMP-dependent protein kinase inhibitor alpha | ENCODES a protein that exhibits cAMP-dependent protein kinase inhibitor activity (ortholog); protein kinase A catalytic subunit binding (ortholog); INVOLVED IN negative regulation of cAMP-dependent protein kinase activity (ortholog); negative regulation of cAMP/PKA signal transduction (ortholog); ne gative regulation of catalytic activity (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 4,4'-diaminodiphenylmethane | 2 | 96306181 | 96380959 | Rat | 116 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 731267 | PKIA | cAMP-dependent protein kinase inhibitor alpha | The protein encoded by this gene is a member of the cAMP-dependent protein kinase (PKA) inhibitor family. This protein was demonstrated to interact with and inhibit the activities of both C alpha and C beta catalytic subunits of the PKA. Alternatively spliced transcript variants encoding the same pr otein have been reported. [provided by RefSeq, Jul 2008] | 8 | 78516340 | 78605267 | Human | 119 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 731268 | Pkia | protein kinase inhibitor, alpha | Enables cAMP-dependent protein kinase inhibitor activity and protein kinase A catalytic subunit binding activity. Acts upstream of or within negative regulation of macromolecule metabolic process; negative regulation of protein import into nucleus; and regulation of G2/M transition of mitotic cell c ycle. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human PKIA (cAMP-dependent protein kinase inhibitor alpha). [provided by Alliance of Genome Resources, Jul 2025] | 3 | 7431695 | 7510426 | Mouse | 125 | symbol , PhenoGen , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 8705978 | Pkia | cAMP-dependent protein kinase inhibitor alpha | ENCODES a protein that exhibits cAMP-dependent protein kinase inhibitor activity (ortholog); protein kinase A catalytic subunit binding (ortholog); INVOLVED IN negative regulation of cAMP-dependent protein kinase activity (ortholog); negative regulation of cAMP/PKA signal transduction (ortholog); ne gative regulation of catalytic activity (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog) | NW_004955444 | 2498785 | 2532881 | Chinchilla | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11812906 | PKIA | cAMP-dependent protein kinase inhibitor alpha | ENCODES a protein that exhibits cAMP-dependent protein kinase inhibitor activity (inferred); protein kinase A catalytic subunit binding (inferred); protein kinase inhibitor activity (inferred); INVOLVED IN negative regulation of cAMP-dependent protein kinase activity (ortholog); negative regulation of catalytic activity (ortholog); negative regulation of protein import into nucleus (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred) | 8 | 75046316 | 75136264 | Bonobo | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12359578 | PKIA | cAMP-dependent protein kinase inhibitor alpha | ENCODES a protein that exhibits protein kinase A catalytic subunit binding (ortholog); INVOLVED IN negative regulation of cAMP-dependent protein kinase activity (ortholog); negative regulation of cAMP/PKA signal transduction (ortholog); negative regulation of catalytic activity (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog) | 29 | 26182842 | 26278838 | Dog | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12714782 | Pkia | cAMP-dependent protein kinase inhibitor alpha | ENCODES a protein that exhibits cAMP-dependent protein kinase inhibitor activity (inferred); protein kinase A catalytic subunit binding (inferred); protein kinase inhibitor activity (inferred); INVOLVED IN negative regulation of cAMP-dependent protein kinase activity (ortholog); negative regulation of catalytic activity (ortholog); negative regulation of protein import into nucleus (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred) | NW_004936702 | 272724 | 365753 | Squirrel | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14156818 | PKIA | cAMP-dependent protein kinase inhibitor alpha | ENCODES a protein that exhibits protein kinase A catalytic subunit binding (ortholog); INVOLVED IN negative regulation of cAMP-dependent protein kinase activity (ortholog); negative regulation of cAMP/PKA signal transduction (ortholog); negative regulation of catalytic activity (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 22 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 18454222 | PKIA | cAMP-dependent protein kinase inhibitor alpha | ENCODES a protein that exhibits cAMP-dependent protein kinase inhibitor activity (inferred); protein kinase A catalytic subunit binding (inferred); protein kinase inhibitor activity (inferred); INVOLVED IN negative regulation of cAMP-dependent protein kinase activity (ortholog); negative regulation of catalytic activity (ortholog); negative regulation of protein import into nucleus (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred) | | | | Green Monkey | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18929016 | Pkia | cAMP-dependent protein kinase inhibitor alpha | ENCODES a protein that exhibits protein kinase A catalytic subunit binding (ortholog); INVOLVED IN negative regulation of cAMP-dependent protein kinase activity (ortholog); negative regulation of cAMP/PKA signal transduction (ortholog); negative regulation of catalytic activity (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog) | | | | Naked Mole-Rat | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155244261 | pkia | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626103533 | Pkia | cAMP-dependent protein kinase inhibitor alpha | ENCODES a protein that exhibits cAMP-dependent protein kinase inhibitor activity (ortholog); protein kinase A catalytic subunit binding (ortholog); INVOLVED IN negative regulation of cAMP-dependent protein kinase activity (ortholog); negative regulation of cAMP/PKA signal transduction (ortholog); ne gative regulation of catalytic activity (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog) | | | | Black Rat | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155238809 | pkia.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155244260 | pkia.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 10002976 | PKIA-AS1 | PKIA antisense RNA 1 | INTERACTS WITH benzo[a]pyrene | 8 | 78533892 | 78558503 | Human | 1 | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 16562724 | AC068700.1 | novel transcript, overlapping to PKIA | | | | | Human | | name | gene, lncrna |