| 1308721 | Tspan32 | tetraspanin 32 | INVOLVED IN blood coagulation (ortholog); cytoskeleton organization (ortholog); defense response to protozoan (ortholog); FOUND IN cell surface (ortholog); integrin alphaIIb-beta3 complex (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 207619566 | 207633885 | Rat | 64 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] | | 1318659 | TSPAN32 | tetraspanin 32 | This gene, which is a member of the tetraspanin superfamily, is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann sy ndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. This gene is located among several imprinted genes; however, this gene, as well as the tumor-suppressing subchromosomal transferable fragment 4, escapes imprinting. This gene may play a role in malignancies and diseases that involve this region, and it is also involved in hematopoietic cell function. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] | 11 | 2302013 | 2318204 | Human | 66 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] | | 1318660 | Tspan32 | tetraspanin 32 | Acts upstream of or within several processes, including defense response to protozoan; integrin-mediated signaling pathway; and negative regulation of leukocyte activation. Located in cell surface. Part of integrin alphaIIb-beta3 complex. Is expressed in several structures, including central nervous system; ganglia; immune system; placenta; and tongue. Orthologous to human TSPAN32 (tetraspanin 32). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 142558644 | 142573223 | Mouse | 84 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] | | 1316004 | TSSC4 | tumor suppressing subtransferable candidate 4 | This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carc inoma, and lung, ovarian, and breast cancer. This gene is located among several imprinted genes; however, this gene, as well as the pan-hematopoietic expression gene (PHEMX), escapes imprinting. This gene may play a role in malignancies and disease that involve this region. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] | 11 | 2400750 | 2403876 | Human | 90 | description | gene, protein-coding, REVIEWED [RefSeq] | |