| 621754 | Pggt1b | protein geranylgeranyltransferase type I subunit beta | ENCODES a protein that exhibits CAAX-protein geranylgeranyltransferase activity; heterocyclic compound binding; peptide binding; INVOLVED IN positive regulation of cell cycle; positive regulation of cell population proliferation; protein geranylgeranylation; ASSOCIATED WITH Lung Neoplasms (ortholog) ; FOUND IN CAAX-protein geranylgeranyltransferase complex; INTERACTS WITH (+)-schisandrin B; ammonium chloride; amphetamine | 18 | 41138536 | 41182145 | Rat | 116 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 734288 | PGGT1B | protein geranylgeranyltransferase type I subunit beta | Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994 [PubMed 8106351]). The enzyme is composed of a 48-kD alpha subunit (FNTA; MIM 134635) and a 43-kD beta subunit, encoded by the PGGT1B gene. The FNTA gene encodes the alpha subunit for both GGTase-I and the related enzyme farnesyltransferase.[supplied by OMIM, Mar 2010] | 5 | 115204012 | 115262877 | Human | 102 | symbol , COSMIC , description , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1332546 | Pggt1b | protein geranylgeranyltransferase type I, beta subunit | Predicted to enable heterocyclic compound binding activity; protein geranylgeranyltransferase activity; and zinc ion binding activity. Predicted to contribute to CAAX-protein geranylgeranyltransferase activity; peptide binding activity; and small molecule binding activity. Predicted to be involved i n several processes, including positive regulation of cell cycle; positive regulation of cell population proliferation; and protein geranylgeranylation. Part of CAAX-protein geranylgeranyltransferase complex. Orthologous to human PGGT1B (protein geranylgeranyltransferase type I subunit beta). [provided by Alliance of Genome Resources, Apr 2025] | 18 | 46368411 | 46414173 | Mouse | 148 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8889248 | Pggt1b | protein geranylgeranyltransferase type I subunit beta | ENCODES a protein that exhibits CAAX-protein geranylgeranyltransferase activity (ortholog); heterocyclic compound binding (ortholog); peptide binding (ortholog); INVOLVED IN CAAX-box protein maturation (ortholog); positive regulation of cell cycle (ortholog); positive regulation of cell population p roliferation (ortholog); ASSOCIATED WITH Lung Neoplasms (ortholog); FOUND IN CAAX-protein geranylgeranyltransferase complex (ortholog) | NW_004955408 | 34994545 | 35049037 | Chinchilla | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11916161 | PGGT1B | protein geranylgeranyltransferase type I subunit beta | ENCODES a protein that exhibits heterocyclic compound binding (ortholog); peptide binding (ortholog); small molecule binding (ortholog); INVOLVED IN positive regulation of cell cycle (ortholog); positive regulation of cell population proliferation (ortholog); protein geranylgeranylation (ortholog); ASSOCIATED WITH Lung Neoplasms (ortholog); FOUND IN CAAX-protein geranylgeranyltransferase complex (ortholog) | 5 | 110558684 | 110622175 | Bonobo | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12364582 | PGGT1B | protein geranylgeranyltransferase type I subunit beta | ENCODES a protein that exhibits CAAX-protein geranylgeranyltransferase activity (ortholog); heterocyclic compound binding (ortholog); peptide binding (ortholog); INVOLVED IN positive regulation of cell cycle (ortholog); positive regulation of cell population proliferation (ortholog); protein geranyl geranylation (ortholog); ASSOCIATED WITH Lung Neoplasms (ortholog); FOUND IN CAAX-protein geranylgeranyltransferase complex (ortholog) | 11 | 4967504 | 5020491 | Dog | 37 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12554245 | Pggt1b | protein geranylgeranyltransferase type I subunit beta | ENCODES a protein that exhibits heterocyclic compound binding (ortholog); peptide binding (ortholog); small molecule binding (ortholog); INVOLVED IN positive regulation of cell cycle (ortholog); positive regulation of cell population proliferation (ortholog); protein geranylgeranylation (ortholog); ASSOCIATED WITH Lung Neoplasms (ortholog); FOUND IN CAAX-protein geranylgeranyltransferase complex (ortholog) | NW_004936742 | 394061 | 450717 | Squirrel | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155239656 | pggt1b | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18437703 | PGGT1B | protein geranylgeranyltransferase type I subunit beta | ENCODES a protein that exhibits heterocyclic compound binding (ortholog); peptide binding (ortholog); small molecule binding (ortholog); INVOLVED IN positive regulation of cell cycle (ortholog); positive regulation of cell population proliferation (ortholog); protein geranylgeranylation (ortholog); ASSOCIATED WITH Lung Neoplasms (ortholog); FOUND IN CAAX-protein geranylgeranyltransferase complex (ortholog) | | | | Green Monkey | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18929349 | Pggt1b | protein geranylgeranyltransferase type I subunit beta | ENCODES a protein that exhibits heterocyclic compound binding (ortholog); peptide binding (ortholog); small molecule binding (ortholog); INVOLVED IN positive regulation of cell cycle (ortholog); positive regulation of cell population proliferation (ortholog); protein geranylgeranylation (ortholog); ASSOCIATED WITH Lung Neoplasms (ortholog); FOUND IN CAAX-protein geranylgeranyltransferase complex (ortholog) | | | | Naked Mole-Rat | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14182805 | PGGT1B | protein geranylgeranyltransferase type I subunit beta | ENCODES a protein that exhibits CAAX-protein geranylgeranyltransferase activity (ortholog); heterocyclic compound binding (ortholog); peptide binding (ortholog); INVOLVED IN positive regulation of cell cycle (ortholog); positive regulation of cell population proliferation (ortholog); protein geranyl geranylation (ortholog); ASSOCIATED WITH Lung Neoplasms (ortholog); FOUND IN CAAX-protein geranylgeranyltransferase complex (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 34 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625906256 | Pggt1b | protein geranylgeranyltransferase type I subunit beta | ENCODES a protein that exhibits CAAX-protein geranylgeranyltransferase activity (ortholog); heterocyclic compound binding (ortholog); peptide binding (ortholog); INVOLVED IN CAAX-box protein maturation (ortholog); positive regulation of cell cycle (ortholog); positive regulation of cell population p roliferation (ortholog); ASSOCIATED WITH Lung Neoplasms (ortholog); FOUND IN CAAX-protein geranylgeranyltransferase complex (ortholog) | | | | Black Rat | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155247005 | pggt1b.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155239657 | pggt1b.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 16566127 | AC008494.3 | novel transcript, antisense to PGGT1B | | | | | Human | | name | gene, lncrna |
| 7206858 | PGGT1BP1 | protein geranylgeranyltransferase type I subunit beta pseudogene 1 | | 10 | 50726645 | 50727993 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 7254810 | PGGT1BP2 | protein geranylgeranyltransferase type I subunit beta pseudogene 2 | | 10 | 79891851 | 79893199 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |