Pcdhgc5 Gene Search Result

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1353179	PCDHGC5	protocadherin gamma subfamily C, 5	This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster ... (more) includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008]	5	141489081	141512975	Human	30	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
1623077	Pcdhgc5	protocadherin gamma subfamily C, 5	Acts upstream of or within negative regulation of neuron apoptotic process and synapse organization. Located in membrane. Is expressed in brain; cerebellum; and cerebral cortex. Orthologous to human PCDHGC5 (protocadherin gamma subfamily C, 5). [provided by Alli ... (more) ance of Genome Resources, Apr 2025]	18	37952599	37974926	Mouse	31	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
2312582	Pcdhgc5	protocadherin gamma subfamily C, 5	ENCODES a protein that exhibits calcium ion binding (inferred); INVOLVED IN negative regulation of neuron apoptotic process (ortholog); synapse organization (ortholog); FOUND IN membrane (ortholog); INTERACTS WITH bisphenol A; 17beta-estradiol (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog)	18	29898430	29917566	Rat	26	symbol , PhenoGen	gene, protein-coding, PROVISIONAL [RefSeq]