| 1352537 | PCDHGA12 | protocadherin gamma subfamily A, 12 | This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008] | 5 | 141430507 | 141512975 | Human | 36 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1587258 | Pcdhga12 | protocadherin gamma subfamily A, 12 | ENCODES a protein that exhibits calcium ion binding (inferred); INVOLVED IN cell adhesion (inferred); homophilic cell-cell adhesion (inferred); FOUND IN cell-cell junction (ortholog); membrane (ortholog); INTERACTS WITH bisphenol A; furan; 17alpha-ethynylestradiol (ortholog) | 18 | 29843897 | 29919095 | Rat | 33 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1623070 | Pcdhga12 | protocadherin gamma subfamily A, 12 | Predicted to be involved in cell adhesion. Predicted to act upstream of or within calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules. Located in cell-cell junction and membrane. Is expressed in several structures, including brain; facial prominence; sensory organ; skele ton; and tooth. Orthologous to human PCDHGA12 (protocadherin gamma subfamily A, 12). [provided by Alliance of Genome Resources, Apr 2025] | 18 | 37898633 | 37974926 | Mouse | 38 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 12715771 | LOC101968618 | protocadherin gamma-A12 | ENCODES a protein that exhibits calcium ion binding (inferred); INVOLVED IN cell adhesion (inferred); homophilic cell-cell adhesion (inferred); FOUND IN cell-cell junction (ortholog) | NW_004936504 | 12711899 | 12720086 | Squirrel | 12 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |