| 1306243 | Parp16 | poly (ADP-ribose) polymerase family, member 16 | ENCODES a protein that exhibits kinase binding (ortholog); NAD+ poly-ADP-ribosyltransferase activity (ortholog); NAD+-protein mono-ADP-ribosyltransferase activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); endoplasmic reticulum unfolded protein response (orth olog); IRE1-mediated unfolded protein response (ortholog); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum tubular network (ortholog); nuclear envelope (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 8 | 74626399 | 74644610 | Rat | 123 | symbol , old_gene_name , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1350046 | PARP16 | poly(ADP-ribose) polymerase family member 16 | Enables kinase binding activity; pentosyltransferase activity; and protein serine/threonine kinase activator activity. Involved in IRE1-mediated unfolded protein response; negative regulation of cytoplasmic translation; and protein auto-ADP-ribosylation. Located in endoplasmic reticulum tubular netw ork and nuclear envelope. [provided by Alliance of Genome Resources, Jul 2025] | 15 | 65230917 | 65286883 | Human | 109 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1551462 | Parp16 | poly (ADP-ribose) polymerase family, member 16 | Predicted to enable kinase binding activity; pentosyltransferase activity; and protein serine/threonine kinase activator activity. Acts upstream of or within cellular response to leukemia inhibitory factor. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic retic ulum tubular network and nuclear envelope. Is expressed in several structures, including alimentary system; brain; connective tissue; genitourinary system; and hemolymphoid system. Orthologous to human PARP16 (poly(ADP-ribose) polymerase family member 16). [provided by Alliance of Genome Resources, Apr 2025] | 9 | 65121918 | 65146502 | Mouse | 123 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8759701 | Parp16 | poly(ADP-ribose) polymerase family member 16 | ENCODES a protein that exhibits kinase binding (ortholog); NAD+ poly-ADP-ribosyltransferase activity (ortholog); NAD+-protein mono-ADP-ribosyltransferase activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); endoplasmic reticulum unfolded protein response (orth olog); IRE1-mediated unfolded protein response (ortholog); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum tubular network (ortholog); nuclear envelope (ortholog) | NW_004955450 | 10157731 | 10177939 | Chinchilla | 19 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11787506 | PARP16 | poly(ADP-ribose) polymerase family member 16 | ENCODES a protein that exhibits glycosyltransferase activity (inferred); kinase binding (inferred); NAD+ poly-ADP-ribosyltransferase activity (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; FOUN D IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); endoplasmic reticulum tubular network (inferred) | 15 | 44163785 | 44231895 | Bonobo | 25 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12081817 | PARP16 | poly(ADP-ribose) polymerase family member 16 | ENCODES a protein that exhibits glycosyltransferase activity (inferred); kinase binding (inferred); NAD+ poly-ADP-ribosyltransferase activity (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; FOUN D IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); endoplasmic reticulum tubular network (inferred) | 30 | 29626675 | 29649992 | Dog | 32 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12670707 | Parp16 | poly(ADP-ribose) polymerase family member 16 | ENCODES a protein that exhibits glycosyltransferase activity (inferred); kinase binding (inferred); NAD+ poly-ADP-ribosyltransferase activity (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; FOUN D IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); endoplasmic reticulum tubular network (inferred) | NW_004936471 | 25561136 | 25580801 | Squirrel | 28 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 155232517 | parp16 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18532745 | PARP16 | poly(ADP-ribose) polymerase family member 16 | ENCODES a protein that exhibits glycosyltransferase activity (inferred); kinase binding (inferred); NAD+ poly-ADP-ribosyltransferase activity (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; FOUN D IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); endoplasmic reticulum tubular network (inferred) | | | | Green Monkey | 25 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 14214574 | PARP16 | poly(ADP-ribose) polymerase family member 16 | ENCODES a protein that exhibits glycosyltransferase activity (inferred); kinase binding (inferred); NAD+ poly-ADP-ribosyltransferase activity (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; FOUN D IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); endoplasmic reticulum tubular network (inferred) | | | | Pig | 32 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18909601 | Parp16 | poly(ADP-ribose) polymerase family member 16 | ENCODES a protein that exhibits kinase binding (ortholog); NAD+-protein mono-ADP-ribosyltransferase activity (ortholog); NAD+-protein-aspartate ADP-ribosyltransferase activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); endoplasmic reticulum unfolded protein r esponse (ortholog); IRE1-mediated unfolded protein response (ortholog); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum tubular network (ortholog); nuclear envelope (ortholog) | | | | Naked Mole-Rat | 25 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 14388301 | Parp16 | | | | | | Fly | | symbol | gene, null |
| 625905393 | Parp16 | poly(ADP-ribose) polymerase family member 16 | ENCODES a protein that exhibits kinase binding (ortholog); NAD+ poly-ADP-ribosyltransferase activity (ortholog); NAD+-protein mono-ADP-ribosyltransferase activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); endoplasmic reticulum unfolded protein response (orth olog); IRE1-mediated unfolded protein response (ortholog); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum tubular network (ortholog); nuclear envelope (ortholog) | | | | Black Rat | 19 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 155245147 | parp16.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 401900154 | Parp16as | poly (ADP-ribose) polymerase family, member 16, antisense RNA | | | | | Mouse | | symbol , PhenoGen | gene, ncrna |