| 1304677 | Pank1 | pantothenate kinase 1 | ENCODES a protein that exhibits acetyl-CoA binding (ortholog); pantothenate kinase activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN coenzyme A biosynthetic process (ortholog); PARTICIPATES IN Fanconi syndrome pathway; fructose-1,6-bisphosphatase deficiency pathway; gluc oneogenesis pathway; ASSOCIATED WITH Nerve Degeneration (ortholog); FOUND IN cell periphery (ortholog); clathrin coat (ortholog); cytoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 17beta-estradiol 3-benzoate | 1 | 241737371 | 241808126 | Rat | 203 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1312259 | PANK1 | pantothenate kinase 1 | This gene encodes a member of the pantothenate kinase family. Pantothenate kinases are key regulatory enzymes in the biosynthesis of coenzyme A (CoA). The encoded protein catalyzes the first and rate-limiting enzymatic reaction in CoA biosynthesis and is regulated by CoA through feedback inhibition. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. This gene and an intronic miRNA on the same strand are co-regulated by the tumor suppressor p53 (see PMID 20833636). [provided by RefSeq, Apr 2011] | 10 | 89579495 | 89645242 | Human | 202 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1312260 | Pank1 | pantothenate kinase 1 | Enables pantothenate kinase activity. Involved in coenzyme A biosynthetic process. Located in cell periphery and cytoplasm. Is active in cytosol. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human PANK1 (pantothenate kinase 1). [provided by Alliance of Genome Resources, Jul 2025] | 19 | 34784335 | 34862420 | Mouse | 244 | symbol , PhenoGen , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 8880676 | Pank1 | pantothenate kinase 1 | ENCODES a protein that exhibits acetyl-CoA binding (ortholog); pantothenate kinase activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN coenzyme A biosynthetic process (ortholog); PARTICIPATES IN Fanconi syndrome pathway; fructose-1,6-bisphosphatase deficiency pathway; gluc oneogenesis pathway; ASSOCIATED WITH Nerve Degeneration (ortholog); FOUND IN cell periphery (ortholog); clathrin coat (ortholog); cytoplasm (ortholog) | NW_004955425 | 3384023 | 3433808 | Chinchilla | 33 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11904272 | PANK1 | pantothenate kinase 1 | ENCODES a protein that exhibits acetyl-CoA binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN coenzyme A biosynthetic process (ortholog); PARTICIPATES IN Fanconi syndrome pathway; fructose-1,6-bisphosphatase deficiency pathway; gluconeogenesis pathway; ASSOCIATED WITH Nerv e Degeneration (ortholog); FOUND IN cell periphery (ortholog); clathrin coat (ortholog); cytosol (ortholog) | 10 | 86302702 | 86428635 | Bonobo | 35 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12165233 | PANK1 | pantothenate kinase 1 | ENCODES a protein that exhibits acetyl-CoA binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN coenzyme A biosynthetic process (ortholog); PARTICIPATES IN Fanconi syndrome pathway; fructose-1,6-bisphosphatase deficiency pathway; gluconeogenesis pathway; ASSOCIATED WITH Nerv e Degeneration (ortholog); FOUND IN clathrin coat (ortholog); nucleus (ortholog); recycling endosome (ortholog) | 28 | 4476920 | 4534501 | Dog | 39 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12682019 | Pank1 | pantothenate kinase 1 | ENCODES a protein that exhibits acetyl-CoA binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN coenzyme A biosynthetic process (ortholog); PARTICIPATES IN Fanconi syndrome pathway; fructose-1,6-bisphosphatase deficiency pathway; gluconeogenesis pathway; ASSOCIATED WITH Nerv e Degeneration (ortholog); FOUND IN clathrin coat (ortholog); recycling endosome (ortholog) | NW_004936601 | 4578132 | 4639305 | Squirrel | 37 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14015196 | PANK1 | pantothenate kinase 1 | ENCODES a protein that exhibits acetyl-CoA binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN coenzyme A biosynthetic process (ortholog); PARTICIPATES IN Fanconi syndrome pathway; fructose-1,6-bisphosphatase deficiency pathway; gluconeogenesis pathway; ASSOCIATED WITH Nerv e Degeneration (ortholog); FOUND IN cell periphery (ortholog); clathrin coat (ortholog); nucleus (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 38 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18750465 | PANK1 | pantothenate kinase 1 | ENCODES a protein that exhibits acetyl-CoA binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN coenzyme A biosynthetic process (ortholog); PARTICIPATES IN Fanconi syndrome pathway; fructose-1,6-bisphosphatase deficiency pathway; gluconeogenesis pathway; ASSOCIATED WITH Nerv e Degeneration (ortholog); FOUND IN cell periphery (ortholog); clathrin coat (ortholog); cytosol (ortholog) | | | | Green Monkey | 34 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 288083230 | pank1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18914001 | Pank1 | pantothenate kinase 1 | ENCODES a protein that exhibits acetyl-CoA binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN coenzyme A biosynthetic process (ortholog); PARTICIPATES IN Fanconi syndrome pathway; fructose-1,6-bisphosphatase deficiency pathway; gluconeogenesis pathway; ASSOCIATED WITH Nerv e Degeneration (ortholog); FOUND IN cell periphery (ortholog); clathrin coat (ortholog); cytosol (ortholog) | | | | Naked Mole-Rat | 35 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625965683 | Pank1 | pantothenate kinase 1 | ENCODES a protein that exhibits acetyl-CoA binding (ortholog); pantothenate kinase activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN coenzyme A biosynthetic process (ortholog); PARTICIPATES IN Fanconi syndrome pathway; fructose-1,6-bisphosphatase deficiency pathway; gluc oneogenesis pathway; ASSOCIATED WITH Nerve Degeneration (ortholog); FOUND IN cell periphery (ortholog); clathrin coat (ortholog); cytoplasm (ortholog) | | | | Black Rat | 33 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 329329263 | pank1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 288083231 | pank1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 38661009 | PANK1-AS1 | PANK1 antisense RNA 1 | | 10 | 89644114 | 89652161 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 1591721 | Pank1-ps1 | pantothenate kinase 1, pseudogene 1 | | 1 | 156137305 | 156145466 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 16558684 | AL157400.5 | pantothenate kinase 1 (PANK1) pseudogene | | | | | Human | | name | gene, processed_pseudogene |