| 735150 | P4ha3 | prolyl 4-hydroxylase subunit alpha 3 | ENCODES a protein that exhibits procollagen-proline 4-dioxygenase activity; PARTICIPATES IN AGAT deficiency pathway; arginine and proline metabolic pathway; guanidinoacetate methyltransferase deficiency pathway; FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum lumen (inferred); proco llagen-proline 4-dioxygenase complex (inferred); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl | 1 | 164040852 | 164075922 | Rat | 75 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1346978 | P4HA3 | prolyl 4-hydroxylase subunit alpha 3 | This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] | 11 | 74250146 | 74311640 | Human | 78 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1551556 | P4ha3 | procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide III | Predicted to enable procollagen-proline 4-dioxygenase activity. Predicted to be involved in collagen fibril organization. Predicted to be located in endoplasmic reticulum lumen. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including alimentary system; central nervous system; ear; respiratory system; and skeleton. Orthologous to human P4HA3 (prolyl 4-hydroxylase subunit alpha 3). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 99934637 | 99968908 | Mouse | 80 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8737378 | P4ha3 | prolyl 4-hydroxylase subunit alpha 3 | ENCODES a protein that exhibits procollagen-proline 4-dioxygenase activity (ortholog); PARTICIPATES IN AGAT deficiency pathway; arginine and proline metabolic pathway; guanidinoacetate methyltransferase deficiency pathway | NW_004955414 | 17344512 | 17376564 | Chinchilla | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11951977 | P4HA3 | prolyl 4-hydroxylase subunit alpha 3 | ENCODES a protein that exhibits procollagen-proline 4-dioxygenase activity (ortholog); PARTICIPATES IN AGAT deficiency pathway; arginine and proline metabolic pathway; guanidinoacetate methyltransferase deficiency pathway; FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum lumen (infer red) | 11 | 69333199 | 69385012 | Bonobo | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12250846 | P4HA3 | prolyl 4-hydroxylase subunit alpha 3 | ENCODES a protein that exhibits procollagen-proline 4-dioxygenase activity (ortholog); PARTICIPATES IN AGAT deficiency pathway; arginine and proline metabolic pathway; guanidinoacetate methyltransferase deficiency pathway; FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum lumen (infer red) | 21 | 23991474 | 24033086 | Dog | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12494438 | P4ha3 | prolyl 4-hydroxylase subunit alpha 3 | ENCODES a protein that exhibits procollagen-proline 4-dioxygenase activity (ortholog); PARTICIPATES IN AGAT deficiency pathway; arginine and proline metabolic pathway; guanidinoacetate methyltransferase deficiency pathway; FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum lumen (infer red) | NW_004936498 | 3313572 | 3346888 | Squirrel | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14134890 | P4HA3 | prolyl 4-hydroxylase subunit alpha 3 | ENCODES a protein that exhibits procollagen-proline 4-dioxygenase activity (ortholog); PARTICIPATES IN AGAT deficiency pathway; arginine and proline metabolic pathway; guanidinoacetate methyltransferase deficiency pathway; FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum lumen (infer red) | | | | Pig | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18900265 | P4ha3 | prolyl 4-hydroxylase subunit alpha 3 | ENCODES a protein that exhibits procollagen-proline 4-dioxygenase activity (ortholog); PARTICIPATES IN AGAT deficiency pathway; arginine and proline metabolic pathway; guanidinoacetate methyltransferase deficiency pathway; FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum lumen (infer red) | | | | Naked Mole-Rat | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626153002 | P4ha3 | prolyl 4-hydroxylase subunit alpha 3 | ENCODES a protein that exhibits procollagen-proline 4-dioxygenase activity (ortholog); PARTICIPATES IN AGAT deficiency pathway; arginine and proline metabolic pathway; guanidinoacetate methyltransferase deficiency pathway | | | | Black Rat | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155248729 | p4ha3 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18612466 | P4HA3 | prolyl 4-hydroxylase subunit alpha 3 | ENCODES a protein that exhibits procollagen-proline 4-dioxygenase activity (ortholog); PARTICIPATES IN AGAT deficiency pathway; arginine and proline metabolic pathway; guanidinoacetate methyltransferase deficiency pathway; FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum lumen (infer red) | | | | Green Monkey | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155241449 | p4ha3.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 12792124 | P4HA3-AS1 | P4HA3 antisense RNA 1 | | 11 | 74311362 | 74324705 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
