| 1560468 | Otud3 | OTU deubiquitinase 3 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (ortholog); INVOLVED IN cellular response to nutrient levels (ortholog); negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (ortholog); protein deubiquitination (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; aflatoxin B1 | 5 | 156419099 | 156445341 | Rat | 67 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1604042 | OTUD3 | OTU deubiquitinase 3 | Enables cysteine-type deubiquitinase activity. Involved in cellular response to nutrient levels and protein deubiquitination. Acts upstream of or within negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; protein deubiquitination; and protein stabilization. Loc ated in cytoplasm. Is active in nucleus. [provided by Alliance of Genome Resources, Jul 2025] | 1 | 19882395 | 19912945 | Human | 76 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1621489 | Otud3 | OTU domain containing 3 | Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in cellular response to nutrient levels; protein deubiquitination; and protein stabilization. Predicted to act upstream of or within negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transd uction; protein K27-linked deubiquitination; and protein K48-linked deubiquitination. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in axial skeleton; olfactory epithelium; pancreas; and vomeronasal organ. Orthologous to human OTUD3 (OTU deubiquitinase 3). [provided by Alliance of Genome Resources, Apr 2025] | 4 | 138618374 | 138641322 | Mouse | 89 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8862373 | Otud3 | OTU deubiquitinase 3 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (ortholog); INVOLVED IN cellular response to nutrient levels (ortholog); negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (ortholog); protein deubiquitination (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog) | NW_004955452 | 488295 | 516162 | Chinchilla | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11933737 | OTUD3 | OTU deubiquitinase 3 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (inferred); cysteine-type peptidase activity (inferred); hydrolase activity (inferred); INVOLVED IN negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (ortholog); protein K11-linked deubiquit ination (ortholog); protein K27-linked deubiquitination (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred) | 1 | 18836697 | 18867568 | Bonobo | 33 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12208669 | OTUD3 | OTU deubiquitinase 3 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (inferred); cysteine-type peptidase activity (inferred); hydrolase activity (inferred); INVOLVED IN negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (ortholog); protein K11-linked deubiquit ination (ortholog); protein K27-linked deubiquitination (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred) | 2 | 78843627 | 78875215 | Dog | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12562376 | Otud3 | OTU deubiquitinase 3 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (inferred); cysteine-type peptidase activity (inferred); hydrolase activity (inferred); INVOLVED IN negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (ortholog); protein K11-linked deubiquit ination (ortholog); protein K27-linked deubiquitination (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred) | NW_004936474 | 5994019 | 6010101 | Squirrel | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13855090 | OTUD3 | OTU deubiquitinase 3 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (inferred); cysteine-type peptidase activity (inferred); hydrolase activity (inferred); INVOLVED IN negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (ortholog); protein K11-linked deubiquit ination (ortholog); protein K27-linked deubiquitination (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred) | | | | Pig | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18912778 | Otud3 | OTU deubiquitinase 3 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (inferred); cysteine-type peptidase activity (inferred); hydrolase activity (inferred); INVOLVED IN cellular response to nutrient levels (ortholog); negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal tran sduction (ortholog); protein K11-linked deubiquitination (ortholog); FOUND IN nucleus (ortholog) | | | | Naked Mole-Rat | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626080275 | Otud3 | OTU deubiquitinase 3 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (ortholog); INVOLVED IN cellular response to nutrient levels (ortholog); negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (ortholog); protein deubiquitination (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog) | | | | Black Rat | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18644645 | OTUD3 | OTU deubiquitinase 3 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (inferred); cysteine-type peptidase activity (inferred); hydrolase activity (inferred); INVOLVED IN negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (ortholog); protein K11-linked deubiquit ination (ortholog); protein K27-linked deubiquitination (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred) | | | | Green Monkey | 33 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155235406 | otud3 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155243018 | otud3.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155248362 | otud3.S | | | | | | African Clawed Frog | | symbol | gene, null |