ENCODES a protein that exhibits nucleotidyltransferase activity (inferred); RNA binding (inferred); INVOLVED IN defense response to virus (inferred); immune system process (inferred); innate immune response (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; aflatoxin B1
Predicted to enable 2'-5'-oligoadenylate synthetase activity and double-stranded RNA binding activity. Predicted to be involved in several processes, including cellular response to cytokine stimulus; regulation of cytokine production; and regulation of innate immune response. Predicted to be located
in mitochondrion and ribosome. Predicted to be active in cytosol; membrane; and nucleoplasm. Predicted to colocalize with cytoplasm. Human ortholog(s) of this gene implicated in immunodeficiency 100. Orthologous to human OAS1 (2'-5'-oligoadenylate synthetase 1). [provided by Alliance of Genome Resources, Jul 2025]