| 621586 | Nrn1 | neuritin 1 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN nervous system development; neuron projection extension (ortholog); presynaptic modulation of chemical synaptic transmission (ortholog); FOUND IN postsynaptic endocytic zone; AMPA glutamate receptor complex (ortholog); extracellular space (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amitrole; bisphenol A | 17 | 28335426 | 28344354 | Rat | 117 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1351872 | NRN1 | neuritin 1 | This gene encodes a member of the neuritin family, and is expressed in postmitotic-differentiating neurons of the developmental nervous system and neuronal structures associated with plasticity in the adult. The expression of this gene can be induced by neural activity and neurotrophins. The encoded protein contains a consensus cleavage signal found in glycosylphoshatidylinositol (GPI)-anchored proteins. The encoded protein promotes neurite outgrowth and arborization, suggesting its role in promoting neuritogenesis. Overexpression of the encoded protein may be associated with astrocytoma progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] | 6 | 5997999 | 6007518 | Human | 118 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1617544 | Nrn1 | neuritin 1 | Enables identical protein binding activity. Involved in presynaptic modulation of chemical synaptic transmission and regulation of synapse maturation. Acts upstream of or within neuron projection extension. Located in extracellular space and plasma membrane. Part of AMPA glutamate receptor complex. Is active in glutamatergic synapse. Is expressed in several structures, including central nervous system; eye; genitourinary system; gut; and liver. Orthologous to human NRN1 (neuritin 1). [provided by Alliance of Genome Resources, Jul 2025] | 13 | 36909596 | 36918451 | Mouse | 137 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 9022740 | Nrn1 | neuritin 1 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN nervous system development (ortholog); neuron projection extension (ortholog); presynaptic modulation of chemical synaptic transmission (ortholog); FOUND IN AMPA glutamate receptor complex (ortholog); extracellular spa ce (ortholog); glutamatergic synapse (ortholog) | NW_004955465 | 7703301 | 7711927 | Chinchilla | 11 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12005655 | NRN1 | neuritin 1 | ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN nervous system development (ortholog); neuron projection extension (ortholog); FOUND IN postsynaptic endocytic zone (ortholog) | 6 | 5832603 | 5841975 | Bonobo | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12412109 | NRN1 | neuritin 1 | ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN nervous system development (ortholog); neuron projection extension (ortholog); FOUND IN postsynaptic endocytic zone (ortholog) | 35 | 6070456 | 6079214 | Dog | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12628321 | Nrn1 | neuritin 1 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN nervous system development (ortholog); neuron projection extension (ortholog); presynaptic modulation of chemical synaptic transmission (ortholog); FOUND IN AMPA glutamate receptor complex (ortholog); extracellular spa ce (ortholog); glutamatergic synapse (ortholog) | NW_004936534 | 6459431 | 6464253 | Squirrel | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14010778 | NRN1 | neuritin 1 | ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN nervous system development (ortholog); neuron projection extension (ortholog); FOUND IN postsynaptic endocytic zone (ortholog) | | | | Pig | 17 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 18585689 | NRN1 | neuritin 1 | ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN nervous system development (ortholog); neuron projection extension (ortholog); FOUND IN postsynaptic endocytic zone (ortholog) | | | | Green Monkey | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18915335 | Nrn1 | neuritin 1 | ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN nervous system development (ortholog); neuron projection extension (ortholog); FOUND IN postsynaptic endocytic zone (ortholog) | | | | Naked Mole-Rat | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 284396121 | nrn1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626014683 | Nrn1 | neuritin 1 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN nervous system development (ortholog); neuron projection extension (ortholog); presynaptic modulation of chemical synaptic transmission (ortholog); FOUND IN AMPA glutamate receptor complex (ortholog); extracellular spa ce (ortholog); glutamatergic synapse (ortholog) | | | | Black Rat | 11 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 284395808 | nrn1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 288057337 | nrn1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 1319310 | Nrn1l | neuritin 1-like | Enables identical protein binding activity. Acts upstream of or within neuron projection extension. Located in axon; extracellular space; and plasma membrane. Is expressed in several structures, including brain; genitourinary system; gut; retina; and spleen. Orthologous to human NRN1 ight:700;'>NRN1L (neuritin 1 like). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 106620199 | 106621655 | Mouse | 37 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1605881 | NRN1L | neuritin 1 like | The protein encoded by this gene is extracellular and enhances both neurite growth and neuronal survival. The encoded protein is found both as a GPI anchored membrane-bound form and as a secreted form. This activity-related ligand functions as a homodimer or heterodimer. [provided by RefSeq, Feb 201 7] | 16 | 67884885 | 67888855 | Human | 36 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 2301010 | Nrn1l | neuritin 1-like | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN neuron projection extension (ortholog); FOUND IN axon (ortholog); extracellular space (ortholog); membrane (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; bisphenol A | 19 | 50696281 | 50697741 | Rat | 30 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 8912141 | Nrn1l | neuritin 1 like | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN neuron projection extension (ortholog); FOUND IN axon (ortholog); extracellular space (ortholog); membrane (ortholog) | NW_004955484 | 8818768 | 8820477 | Chinchilla | 8 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11916578 | NRN1L | neuritin 1 like | ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN neuron projection extension (ortholog); FOUND IN axon (inferred); extracellular space (inferred); membrane (inferred) | 16 | 48226206 | 48230470 | Bonobo | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12346471 | NRN1L | neuritin 1 like | ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN neuron projection extension (ortholog); FOUND IN axon (inferred); extracellular space (inferred); membrane (inferred) | 5 | 81600442 | 81602175 | Dog | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12541472 | Nrn1l | neuritin 1 like | ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN neuron projection extension (ortholog); FOUND IN axon (inferred); extracellular space (inferred); membrane (inferred) | NW_004936475 | 18244787 | 18246303 | Squirrel | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14047535 | NRN1L | neuritin 1 like | ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN neuron projection extension (ortholog); FOUND IN axon (inferred); extracellular space (inferred); membrane (inferred) | | | | Pig | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18456013 | NRN1L | neuritin 1 like | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN neuron projection extension (ortholog); FOUND IN axon (ortholog); extracellular space (ortholog); membrane (ortholog) | | | | Green Monkey | 8 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18918070 | Nrn1l | neuritin 1 like | ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN neuron projection extension (ortholog); FOUND IN axon (inferred); extracellular space (inferred); membrane (inferred) | | | | Naked Mole-Rat | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 20865991 | NRN1L | neuritin 1 like | ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN nervous system development (inferred); neuron projection extension (inferred); FOUND IN axon (inferred); extracellular space (inferred); membrane (inferred) | | | | Green Monkey | 10 | symbol | gene, protein-coding |
| 286611659 | nrn1l | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626082776 | Nrn1l | neuritin 1 like | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN neuron projection extension (ortholog); FOUND IN axon (ortholog); extracellular space (ortholog); membrane (ortholog) | | | | Black Rat | 8 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 288057085 | nrn1l.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 286611933 | nrn1l.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 1562009 | Edc4 | enhancer of mRNA decapping 4 | INVOLVED IN deadenylation-independent decapping of nuclear-transcribed mRNA (inferred); nervous system development (inferred); PARTICIPATES IN microRNA pathway; RNA degradation pathway; FOUND IN cytoplasmic ribonucleoprotein granule (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS W ITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 19 | 50683924 | 50695916 | Rat | 77 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |