| 735102 | Mybpc1 | myosin binding protein C1 | ENCODES a protein that exhibits myosin binding (ortholog); INVOLVED IN cardiac muscle contraction (inferred); cell adhesion (inferred); muscle contraction (inferred); ASSOCIATED WITH congenital myopathy (ortholog); congenital myopathy 16 (ortholog); distal arthrogryposis (ortholog); FOUND IN myosin filament (inferred); INTERACTS WITH 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 7 | 24817770 | 24903681 | Rat | 88 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1351602 | MYBPC1 | myosin binding protein C1 | This gene encodes a member of the myosin-binding protein C family. Myosin-binding protein C family members are myosin-associated proteins found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The encoded protein is the slow skeletal muscle isoform of myosin-binding protein C and plays an important role in muscle contraction by recruiting muscle-type creatine kinase to myosin filaments. Mutations in this gene are associated with distal arthrogryposis type I. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] | 12 | 101594971 | 101695841 | Human | 152 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1550682 | Mybpc1 | myosin binding protein C, slow-type | Predicted to enable myosin binding activity. Predicted to be involved in sarcomere organization. Predicted to act upstream of or within muscle contraction. Predicted to be located in cytoskeleton. Predicted to be active in M band. Is expressed in several structures, including brain; hindlimb; reprod uctive system; skeletal musculature; and urinary system. Used to study congenital myopathy. Human ortholog(s) of this gene implicated in congenital myopathy 16; distal arthrogryposis type 1B; and lethal congenital contracture syndrome 4. Orthologous to human MYBPC1 (myosin binding protein C1). [provided by Alliance of Genome Resources, Jul 2025] | 10 | 88354141 | 88441051 | Mouse | 96 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8927112 | Mybpc1 | myosin binding protein C1 | ENCODES a protein that exhibits myosin binding (ortholog); ASSOCIATED WITH congenital myopathy (ortholog); congenital myopathy 16 (ortholog); distal arthrogryposis (ortholog) | NW_004955405 | 36992798 | 37066154 | Chinchilla | 11 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11978009 | MYBPC1 | myosin binding protein C1 | ENCODES a protein that exhibits actin binding (inferred); myosin binding (inferred); structural constituent of muscle (inferred); INVOLVED IN cell adhesion (inferred); sarcomere organization (inferred); ASSOCIATED WITH congenital myopathy (ortholog); congenital myopathy 16 (ortholog); distal arthrog ryposis (ortholog); FOUND IN M band (inferred); myosin filament (inferred) | 12 | 99179611 | 99269521 | Bonobo | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12184991 | MYBPC1 | myosin binding protein C1 | ENCODES a protein that exhibits actin binding (inferred); myosin binding (inferred); INVOLVED IN cell adhesion (inferred); ASSOCIATED WITH congenital myopathy (ortholog); congenital myopathy 16 (ortholog); distal arthrogryposis (ortholog); FOUND IN myosin filament (inferred) | 15 | 40504974 | 40590441 | Dog | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12686552 | Mybpc1 | myosin binding protein C1 | ENCODES a protein that exhibits actin binding (inferred); myosin binding (inferred); INVOLVED IN cardiac muscle contraction (inferred); cell adhesion (inferred); sarcomere organization (inferred); ASSOCIATED WITH congenital myopathy (ortholog); congenital myopathy 16 (ortholog); distal arthrogryposi s (ortholog); FOUND IN M band (inferred); myosin filament (inferred) | NW_004936492 | 12373240 | 12455371 | Squirrel | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 285696947 | mybpc1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18914797 | Mybpc1 | myosin binding protein C1 | ENCODES a protein that exhibits myosin binding (ortholog); INVOLVED IN cardiac muscle contraction (inferred); cell adhesion (inferred); sarcomere organization (inferred); ASSOCIATED WITH congenital myopathy (ortholog); congenital myopathy 16 (ortholog); distal arthrogryposis (ortholog); FOUND IN M b and (inferred); myosin filament (inferred) | | | | Naked Mole-Rat | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14170127 | MYBPC1 | myosin binding protein C1 | ENCODES a protein that exhibits actin binding (inferred); myosin binding (inferred); INVOLVED IN cell adhesion (inferred); ASSOCIATED WITH congenital myopathy (ortholog); congenital myopathy 16 (ortholog); distal arthrogryposis (ortholog); FOUND IN myosin filament (inferred); INTERACTS WITH deoxyniv alenol | | | | Pig | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18510695 | MYBPC1 | myosin binding protein C1 | ENCODES a protein that exhibits actin binding (inferred); myosin binding (inferred); structural constituent of muscle (inferred); INVOLVED IN cell adhesion (inferred); sarcomere organization (inferred); ASSOCIATED WITH congenital myopathy (ortholog); congenital myopathy 16 (ortholog); distal arthrog ryposis (ortholog); FOUND IN M band (inferred); myosin filament (inferred) | | | | Green Monkey | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625976697 | Mybpc1 | myosin binding protein C1 | ENCODES a protein that exhibits myosin binding (ortholog); ASSOCIATED WITH congenital myopathy (ortholog); congenital myopathy 16 (ortholog); distal arthrogryposis (ortholog) | | | | Black Rat | 11 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 285697667 | mybpc1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 284802559 | mybpc1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 16561344 | AC117505.1 | novel transcript, antisense to MYBPC1 | | | | | Human | | name | gene, lncrna |
