| 1309828 | Irag1 | inositol 1,4,5-triphosphate receptor associated 1 | INVOLVED IN negative regulation of smooth muscle contraction (ortholog); phosphatidylinositol-mediated signaling (ortholog); relaxation of vascular associated smooth muscle (ortholog); FOUND IN cytoplasm (inferred); membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-th iouracil; bisphenol A | 1 | 174416383 | 174528913 | Rat | 100 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1320377 | IRAG1 | inositol 1,4,5-triphosphate receptor associated 1 | This gene is similar to a putative mouse tumor suppressor gene (Mrvi1) that is frequently disrupted by mouse AIDS-related virus (MRV). The encoded protein, which is found in the membrane of the endoplasmic reticulum, is similar to Jaw1, a lymphoid-restricted pro tein whose expression is down-regulated during lymphoid differentiation. This protein is a substrate of cGMP-dependent kinase-1 (PKG1) that can function as a regulator of IP3-induced calcium release. Studies in mouse suggest that MRV integration at Mrvi1 induces myeloid leukemia by altering the expression of a gene important for myeloid cell growth and/or differentiation, and thus this gene may function as a myeloid leukemia tumor suppressor gene. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene, and alternative translation start sites, including a non-AUG (CUG) start site, are used. [provided by RefSeq, May 2011] | 11 | 10573095 | 10693755 | Human | 103 | old_gene_name , description , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1320378 | Irag1 | inositol 1,4,5-triphosphate receptor associated 1 | This gene is a putative tumor suppressor gene that is frequently disrupted by mouse AIDS-related virus (MRV). The encoded protein participates in signaling by nitric oxide (NO) to inhibit intracellular calcium release and platelet aggregation in cardiovascular tissue. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2013] | 7 | 110467464 | 110582116 | Mouse | 140 | old_gene_name , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 8940088 | Irag1 | inositol 1,4,5-triphosphate receptor associated 1 | INVOLVED IN negative regulation of smooth muscle contraction (ortholog); phosphatidylinositol-mediated signaling (ortholog); relaxation of vascular associated smooth muscle (ortholog) | NW_004955414 | 26185226 | 26297647 | Chinchilla | 5 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12023311 | IRAG1 | inositol 1,4,5-triphosphate receptor associated 1 | INVOLVED IN negative regulation of smooth muscle contraction (ortholog); phosphatidylinositol-mediated signaling (ortholog); relaxation of vascular associated smooth muscle (ortholog); FOUND IN cytoplasm (inferred); membrane (inferred) | 11 | 10708215 | 10828102 | Bonobo | 7 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12215356 | IRAG1 | inositol 1,4,5-triphosphate receptor associated 1 | INVOLVED IN negative regulation of smooth muscle contraction (ortholog); phosphatidylinositol-mediated signaling (ortholog); relaxation of vascular associated smooth muscle (ortholog); FOUND IN cytoplasm (inferred); membrane (inferred) | 21 | 33737154 | 33862802 | Dog | 7 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12703544 | Irag1 | inositol 1,4,5-triphosphate receptor associated 1 | INVOLVED IN negative regulation of smooth muscle contraction (ortholog); phosphatidylinositol-mediated signaling (ortholog); relaxation of vascular associated smooth muscle (ortholog); FOUND IN cytoplasm (inferred); membrane (inferred) | NW_004936528 | 7663732 | 7781679 | Squirrel | 7 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 18581897 | IRAG1 | inositol 1,4,5-triphosphate receptor associated 1 | INVOLVED IN negative regulation of smooth muscle contraction (ortholog); phosphatidylinositol-mediated signaling (ortholog); relaxation of vascular associated smooth muscle (ortholog); FOUND IN cytoplasm (inferred); membrane (inferred) | | | | Green Monkey | 7 | old_gene_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 18905835 | Irag1 | inositol 1,4,5-triphosphate receptor associated 1 | INVOLVED IN negative regulation of smooth muscle contraction (ortholog); phosphatidylinositol-mediated signaling (ortholog); relaxation of vascular associated smooth muscle (ortholog); FOUND IN cytoplasm (inferred); membrane (inferred) | | | | Naked Mole-Rat | 7 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 14185038 | IRAG1 | inositol 1,4,5-triphosphate receptor associated 1 | INVOLVED IN negative regulation of smooth muscle contraction (ortholog); phosphatidylinositol-mediated signaling (ortholog); relaxation of vascular associated smooth muscle (ortholog); FOUND IN cytoplasm (inferred); membrane (inferred) | | | | Pig | 7 | old_gene_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 5552950 | IRAG1-AS1 | IRAG1 antisense RNA 1 | INTERACTS WITH aflatoxin B1; benzo[a]pyrene; propanal | 11 | 10541236 | 10599932 | Human | 3 | old_gene_name , old_gene_symbol | gene, ncrna, VALIDATED [RefSeq] |
| 625974458 | Irag1 | inositol 1,4,5-triphosphate receptor associated 1 | INVOLVED IN negative regulation of smooth muscle contraction (ortholog); phosphatidylinositol-mediated signaling (ortholog); relaxation of vascular associated smooth muscle (ortholog) | | | | Black Rat | 5 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
