| 1311376 | Mmp19 | matrix metallopeptidase 19 | ENCODES a protein that exhibits metalloendopeptidase activity (ortholog); INVOLVED IN luteolysis; ovarian follicle development; ovulation from ovarian follicle; ASSOCIATED WITH Cavitary Optic Disc Anomalies (ortholog); COVID-19 (ortholog); interstitial lung disease 2 (ortholog); FOUND IN extracellul ar matrix (inferred); extracellular region (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 6-propyl-2-thiouracil | 7 | 1805732 | 1814054 | Rat | 125 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1322803 | MMP19 | matrix metallopeptidase 19 | This gene encodes a member of a family of proteins that are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded protein is secreted as an inactive proprotein, which is activated upon cleavage by extracellular proteases. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Jan 2013] | 12 | 55835433 | 55842936 | Human | 147 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1322804 | Mmp19 | matrix metallopeptidase 19 | This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded preproprotein undergoes proteolytic processing to generate a mature, zinc-d ependent endopeptidase enzyme. Mice lacking the encoded protein develop a diet-induced obesity due to adipocyte hypertophy, exhibit decreased susceptibility to chemical carcinogen-induced skin tumors and early onset of tumoral angiogenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016] | 10 | 128626779 | 128636696 | Mouse | 153 | symbol , PhenoGen | gene, protein-coding, REVIEWED [RefSeq] |
| 9020974 | Mmp19 | matrix metallopeptidase 19 | ENCODES a protein that exhibits metalloendopeptidase activity (ortholog); INVOLVED IN luteolysis (ortholog); ovarian follicle development (ortholog); ovulation from ovarian follicle (ortholog); ASSOCIATED WITH Cavitary Optic Disc Anomalies (ortholog); COVID-19 (ortholog); interstitial lung disease 2 (ortholog) | NW_004955458 | 3473279 | 3479620 | Chinchilla | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11809379 | MMP19 | matrix metallopeptidase 19 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN luteolysis (ortholog); ovarian follicle development (ortholog); ovulation from ovarian follicle (ortholog); ASSOCIATED WITH Cavitary Optic Disc Anomalies (ortholog); COVID-19 (ortholog); interstitial lung disease 2 (ortholog); FOUND IN extracellular matrix (inferred); extracellular region (inferred); extracellular space (inferred) | 12 | 33068282 | 33075324 | Bonobo | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12171186 | MMP19 | matrix metallopeptidase 19 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN luteolysis (ortholog); ovarian follicle development (ortholog); ovulation from ovarian follicle (ortholog); ASSOCIATED WITH Cavitary Optic Disc Anomalies (ortholog); COVID-19 (ortholog); interstitial lung disease 2 (ortholog); FOUND IN extracellular matrix (inferred); extracellular region (inferred) | 10 | 219193 | 224873 | Dog | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12596467 | Mmp19 | matrix metallopeptidase 19 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN luteolysis (ortholog); ovarian follicle development (ortholog); ovulation from ovarian follicle (ortholog); ASSOCIATED WITH Cavitary Optic Disc Anomalies (ortholog); COVID-19 (ortholog); interstitial lung disease 2 (ortholog); FOUND IN extracellular matrix (inferred); extracellular region (inferred); extracellular space (inferred) | NW_004936646 | 298854 | 304479 | Squirrel | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18737264 | MMP19 | matrix metallopeptidase 19 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN luteolysis (ortholog); ovarian follicle development (ortholog); ovulation from ovarian follicle (ortholog); ASSOCIATED WITH Cavitary Optic Disc Anomalies (ortholog); COVID-19 (ortholog); interstitial lung disease 2 (ortholog); FOUND IN extracellular matrix (inferred); extracellular space (inferred) | | | | Green Monkey | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18912202 | Mmp19 | matrix metallopeptidase 19 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN luteolysis (ortholog); ovarian follicle development (ortholog); ovulation from ovarian follicle (ortholog); ASSOCIATED WITH Cavitary Optic Disc Anomalies (ortholog); COVID-19 (ortholog); interstitial lung disease 2 (ortholog); FOUND IN cytoplasm (inferred); extracellular matrix (inferred); extracellular region (inferred) | | | | Naked Mole-Rat | 33 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 20866120 | MMP19 | matrix metallopeptidase 19 | | | | | Green Monkey | | symbol | gene, protein-coding |
| 155252152 | mmp19 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14187297 | MMP19 | matrix metallopeptidase 19 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN luteolysis (ortholog); ovarian follicle development (ortholog); ovulation from ovarian follicle (ortholog); ASSOCIATED WITH Cavitary Optic Disc Anomalies (ortholog); COVID-19 (ortholog); interstitial lung disease 2 (ortholog); FOUND IN extracellular matrix (inferred); extracellular region (inferred) | | | | Pig | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626090746 | Mmp19 | matrix metallopeptidase 19 | ENCODES a protein that exhibits metalloendopeptidase activity (ortholog); INVOLVED IN luteolysis (ortholog); ovarian follicle development (ortholog); ovulation from ovarian follicle (ortholog); ASSOCIATED WITH Cavitary Optic Disc Anomalies (ortholog); COVID-19 (ortholog); interstitial lung disease 2 (ortholog) | | | | Black Rat | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155250334 | mmp19.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 626184411 | mmp19l | | | | | | Tropical Clawed Frog | | symbol | gene, null |