ENCODES a protein that exhibits chromatin binding (ortholog); DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); INVOLVED IN cell cycle G1/S phase transition (ortholog); DNA damage checkpoint signaling (ortholog); DNA repair (ortholog); FOUND
Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in DNA-templated transcription; in utero embryonic development; and regulation of gene expression
. Predicted to be located in Cajal body. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; gut; and hemolymphoid system gland. Orthologous to human HINFP (histone H4 transcription factor). [provided by Alliance of Genome Resources, Jul 2025]
This gene encodes a transcription factor that interacts with methyl-CpG-binding protein-2 (MBD2), a component of the MeCP1 histone deacetylase (HDAC) complex, and plays a role in DNA methylation and transcription repression. Alternatively spliced transcript variants have been found for this gene.[pr
ENCODES a protein that exhibits chromatin binding (inferred); DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); INVOLVED IN cell cycle G1/S phase transition (inferred); DNA damage checkpoint signaling (inferred); DNA repair (inferred); FOUND