| 1306160 | Lrp1b | LDL receptor related protein 1B | ENCODES a protein that exhibits low-density lipoprotein particle receptor activity (ortholog); INVOLVED IN cholesterol homeostasis; in utero embryonic development (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); cancer (ortholog); chronic obstructive pulmonary disease (ortholog); FOUND IN membrane (ortholog); receptor complex (ortholog); INTERACTS WITH 1,3,4-thiadiazole; 17alpha-ethynylestradiol; 6-propyl-2-thiouracil | 3 | 45004001 | 47125147 | Rat | 86 | symbol , PhenoGen | gene, protein-coding, MODEL [RefSeq] |
| 1314617 | LRP1B | LDL receptor related protein 1B | This gene encodes a member of the low density lipoprotein (LDL) receptor family. These receptors play a wide variety of roles in normal cell function and development due to their interactions with multiple ligands. Disruption of this gene has been reported in several types of cancer. [provided by Re fSeq, Jun 2016] | 2 | 140231423 | 142131016 | Human | 108 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1314618 | Lrp1b | low density lipoprotein-related protein 1B | Enables low-density lipoprotein particle receptor activity. Acts upstream of or within in utero embryonic development. Located in membrane. Is expressed in several structures, including adrenal medulla; central nervous system; and eye. Human ortholog(s) of this gene implicated in gastrointestinal sy stem cancer (multiple); lung disease (multiple); and melanoma. Orthologous to human LRP1B (LDL receptor related protein 1B). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 40485302 | 42543747 | Mouse | 95 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8784459 | Lrp1b | LDL receptor related protein 1B | ENCODES a protein that exhibits low-density lipoprotein particle receptor activity (ortholog); INVOLVED IN cholesterol homeostasis (ortholog); in utero embryonic development (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); cancer (ortholog); chronic obstructive pulmonary disease (ortholog ); FOUND IN membrane (ortholog); receptor complex (ortholog) | NW_004955440 | 7048527 | 8475566 | Chinchilla | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12005496 | LRP1B | LDL receptor related protein 1B | ENCODES a protein that exhibits calcium ion binding (inferred); low-density lipoprotein particle receptor activity (inferred); INVOLVED IN cholesterol homeostasis (ortholog); in utero embryonic development (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); cancer (ortholog); chronic obstruc tive pulmonary disease (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); receptor complex (inferred) | 2B | 17702178 | 19611567 | Bonobo | 35 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12223301 | LRP1B | LDL receptor related protein 1B | ENCODES a protein that exhibits calcium ion binding (inferred); INVOLVED IN cholesterol homeostasis (ortholog); in utero embryonic development (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); cancer (ortholog); chronic obstructive pulmonary disease (ortholog); FOUND IN membrane (inferred) ; receptor complex (inferred) | 19 | 42608167 | 44427492 | Dog | 35 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12579423 | Lrp1b | LDL receptor related protein 1B | ENCODES a protein that exhibits calcium ion binding (inferred); low-density lipoprotein particle receptor activity (inferred); INVOLVED IN cholesterol homeostasis (ortholog); in utero embryonic development (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); cancer (ortholog); chronic obstruc tive pulmonary disease (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); receptor complex (inferred) | NW_004936469 | 35000773 | 36160216 | Squirrel | 37 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18583654 | LRP1B | LDL receptor related protein 1B | ENCODES a protein that exhibits calcium ion binding (inferred); low-density lipoprotein particle receptor activity (inferred); INVOLVED IN cholesterol homeostasis (ortholog); in utero embryonic development (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); cancer (ortholog); chronic obstruc tive pulmonary disease (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); receptor complex (inferred) | | | | Green Monkey | 35 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18917220 | Lrp1b | LDL receptor related protein 1B | ENCODES a protein that exhibits calcium ion binding (inferred); low-density lipoprotein particle receptor activity (inferred); INVOLVED IN cholesterol homeostasis (ortholog); in utero embryonic development (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); cancer (ortholog); chronic obstruc tive pulmonary disease (ortholog); FOUND IN membrane (ortholog) | | | | Naked Mole-Rat | 38 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 598153965 | lrp1b | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14152118 | LRP1B | LDL receptor related protein 1B | ENCODES a protein that exhibits low-density lipoprotein particle receptor activity (ortholog); INVOLVED IN cholesterol homeostasis (ortholog); in utero embryonic development (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); cancer (ortholog); chronic obstructive pulmonary disease (ortholog ); FOUND IN membrane (inferred); receptor complex (inferred) | | | | Pig | 33 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 598151368 | lrp1b | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 598152262 | lrp1b | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 598151373 | lrp1b | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626171838 | lrp1b.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 626186503 | lrp1b.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 626178572 | lrp1b.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 16557850 | AC078882.1 | novel transcript, sense overlapping to LRP1B | | | | | Human | | name | gene, lncrna |
