| 1307105 | Klhdc3 | kelch domain containing 3 | ENCODES a protein that exhibits chromatin binding (ortholog); ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); ubiquitin-dependent protein catabolic process via the C-end degron rule pathway (orthol og); FOUND IN chromatin (ortholog); Cul2-RING ubiquitin ligase complex (ortholog); cytoplasm (ortholog); INTERACTS WITH acrylamide; bis(2-ethylhexyl) phthalate; bisphenol A | 9 | 21799870 | 21806337 | Rat | 85 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1316101 | KLHDC3 | kelch domain containing 3 | The protein encoded by this gene contains six repeated kelch motifs that are structurally similar to recombination activating gene 2, a protein involved in the activation of the V(D)J recombination. In mouse, this gene is found to be expressed specifically in testis. Its expression in pachytene sper matocytes is localized to cytoplasma and meiotic chromatin, suggesting that this gene may be involved in meiotic recombination. [provided by RefSeq, Jun 2012] | 6 | 43014249 | 43021294 | Human | 88 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1622274 | Klhdc3 | kelch domain containing 3 | Predicted to enable chromatin binding activity and ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in ubiquitin-dependent protein catabolic process via the C-end degron rule pathway. Located in chromatin and cytoplasm. Orthologous to human KLHDC3 HDC3 (kelch domain containing 3). [provided by Alliance of Genome Resources, Jul 2025] | 17 | 46985476 | 46991856 | Mouse | 90 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8862774 | Klhdc3 | kelch domain containing 3 | ENCODES a protein that exhibits chromatin binding (ortholog); ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); ubiquitin-dependent protein catabolic process via the C-end degron rule pathway (orthol og); FOUND IN chromatin (ortholog); Cul2-RING ubiquitin ligase complex (ortholog); cytoplasm (ortholog) | NW_004955437 | 8989671 | 8995845 | Chinchilla | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11716257 | KLHDC3 | kelch domain containing 3 | ENCODES a protein that exhibits chromatin binding (inferred); ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN meiotic cell cycle (inferred); proteasome-mediated ubiquitin-dependent protein catabolic process (inferred); ubiquitin-dependent protein catabolic process via the C- end degron rule pathway (inferred); FOUND IN chromatin (inferred); Cul2-RING ubiquitin ligase complex (inferred); cytoplasm (inferred) | 6 | 42606462 | 42613565 | Bonobo | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12418077 | KLHDC3 | kelch domain containing 3 | ENCODES a protein that exhibits chromatin binding (inferred); ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN meiotic cell cycle (inferred); proteasome-mediated ubiquitin-dependent protein catabolic process (inferred); ribosome biogenesis (inferred); FOUND IN chromatin (infe rred); Cul2-RING ubiquitin ligase complex (inferred); cytoplasm (inferred) | 12 | 11542449 | 11549012 | Dog | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12586686 | Klhdc3 | kelch domain containing 3 | ENCODES a protein that exhibits chromatin binding (inferred); ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN meiotic cell cycle (inferred); proteasome-mediated ubiquitin-dependent protein catabolic process (inferred); ubiquitin-dependent protein catabolic process via the C- end degron rule pathway (inferred); FOUND IN chromatin (inferred); Cul2-RING ubiquitin ligase complex (inferred); cytoplasm (inferred) | NW_004936476 | 16913494 | 16920108 | Squirrel | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625880461 | Klhdc3 | kelch domain containing 3 | ENCODES a protein that exhibits chromatin binding (ortholog); ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); ubiquitin-dependent protein catabolic process via the C-end degron rule pathway (orthol og); FOUND IN chromatin (ortholog); Cul2-RING ubiquitin ligase complex (ortholog); cytoplasm (ortholog) | | | | Black Rat | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18395397 | KLHDC3 | kelch domain containing 3 | ENCODES a protein that exhibits chromatin binding (inferred); ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN meiotic cell cycle (inferred); proteasome-mediated ubiquitin-dependent protein catabolic process (inferred); ubiquitin-dependent protein catabolic process via the C- end degron rule pathway (inferred); FOUND IN chromatin (inferred); Cul2-RING ubiquitin ligase complex (inferred); cytoplasm (inferred) | | | | Green Monkey | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18902680 | Klhdc3 | kelch domain containing 3 | ENCODES a protein that exhibits chromatin binding (inferred); ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN meiotic cell cycle (inferred); proteasome-mediated ubiquitin-dependent protein catabolic process (inferred); ubiquitin-dependent protein catabolic process via the C- end degron rule pathway (inferred); FOUND IN chromatin (inferred); Cul2-RING ubiquitin ligase complex (inferred); cytoplasm (inferred) | | | | Naked Mole-Rat | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13967864 | KLHDC3 | kelch domain containing 3 | ENCODES a protein that exhibits chromatin binding (inferred); ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN meiotic cell cycle (inferred); proteasome-mediated ubiquitin-dependent protein catabolic process (inferred); ubiquitin-dependent protein catabolic process via the C- end degron rule pathway (inferred); FOUND IN chromatin (inferred); Cul2-RING ubiquitin ligase complex (inferred); cytoplasm (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 18 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 155230919 | klhdc3 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155241231 | klhdc3.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405858971 | klhdc3.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405857806 | klhdc3.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 626187010 | klhdc3.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 626186223 | klhdc3.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405861905 | klhdc3.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405857396 | klhdc3.S | | | | | | African Clawed Frog | | symbol | gene, null |
