| 1345390 | KCNK5 | potassium two pore domain channel subfamily K member 5 | This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is mainly expressed in the cortical distal tubules and collecting ducts of the kidney. The protein is highly sensitive to external pH and this, in co mbination with its expression pattern, suggests it may play an important role in renal potassium transport. [provided by RefSeq, Jul 2008] | 6 | 39188971 | 39229475 | Human | 143 | symbol , old_gene_name , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1558222 | Kcnk5 | potassium channel, subfamily K, member 5 | Enables voltage-gated potassium channel activity. Acts upstream of or within potassium ion import across plasma membrane. Predicted to be active in plasma membrane. Is expressed in brain; brain meninges; and heart. Orthologous to human KCNK5 (potassium two pore domain channel subfamily K member 5). [provided by Alliance of Genome Resources, Jul 2025] | 14 | 20190125 | 20231850 | Mouse | 148 | symbol , old_gene_name , PhenoGen , description , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1564985 | Kcnk5 | potassium two pore domain channel subfamily K member 5 | ENCODES a protein that exhibits outward rectifier potassium channel activity (ortholog); potassium channel activity (ortholog); protein heterodimerization activity (ortholog); INVOLVED IN potassium ion export across plasma membrane (ortholog); potassium ion import across plasma membrane (ortholog); potassium ion transport (ortholog); ASSOCIATED WITH status epilepticus (ortholog); FOUND IN membrane (inferred); INTERACTS WITH (+)-pilocarpine; 1-naphthyl isothiocyanate; 2,3,4,7,8-Pentachlorodibenzofuran | 15 | 4171625 | 4213896 | Rat | 139 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8874612 | Kcnk5 | potassium two pore domain channel subfamily K member 5 | ENCODES a protein that exhibits outward rectifier potassium channel activity (ortholog); potassium channel activity (ortholog); protein heterodimerization activity (ortholog); INVOLVED IN potassium ion export across plasma membrane (ortholog); potassium ion import across plasma membrane (ortholog); potassium ion transport (ortholog); ASSOCIATED WITH status epilepticus (ortholog) | NW_004955437 | 4275806 | 4313772 | Chinchilla | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11815629 | KCNK5 | potassium two pore domain channel subfamily K member 5 | ENCODES a protein that exhibits voltage-gated potassium channel activity (ortholog); INVOLVED IN potassium ion export across plasma membrane (ortholog); potassium ion import across plasma membrane (ortholog); regulation of resting membrane potential (ortholog); ASSOCIATED WITH status epilepticus (or tholog); FOUND IN membrane (inferred); plasma membrane (inferred) | 6 | 38778331 | 38818792 | Bonobo | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12251227 | KCNK5 | potassium two pore domain channel subfamily K member 5 | ENCODES a protein that exhibits voltage-gated potassium channel activity (ortholog); INVOLVED IN potassium ion export across plasma membrane (ortholog); potassium ion import across plasma membrane (ortholog); regulation of resting membrane potential (ortholog); ASSOCIATED WITH status epilepticus (or tholog); FOUND IN membrane (inferred) | 12 | 8115839 | 8154716 | Dog | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12503167 | Kcnk5 | potassium two pore domain channel subfamily K member 5 | ENCODES a protein that exhibits outward rectifier potassium channel activity (inferred); potassium channel activity (inferred); potassium ion leak channel activity (inferred); INVOLVED IN potassium ion import across plasma membrane (ortholog); regulation of resting membrane potential (ortholog); ASS OCIATED WITH status epilepticus (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | NW_004936476 | 20410631 | 20452172 | Squirrel | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625908216 | Kcnk5 | potassium two pore domain channel subfamily K member 5 | ENCODES a protein that exhibits outward rectifier potassium channel activity (ortholog); potassium channel activity (ortholog); protein heterodimerization activity (ortholog); INVOLVED IN potassium ion export across plasma membrane (ortholog); potassium ion import across plasma membrane (ortholog); potassium ion transport (ortholog); ASSOCIATED WITH status epilepticus (ortholog) | | | | Black Rat | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18936564 | Kcnk5 | potassium two pore domain channel subfamily K member 5 | ENCODES a protein that exhibits outward rectifier potassium channel activity (inferred); potassium channel activity (inferred); potassium ion leak channel activity (inferred); INVOLVED IN potassium ion import across plasma membrane (ortholog); regulation of resting membrane potential (ortholog); ASS OCIATED WITH status epilepticus (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Naked Mole-Rat | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14214664 | KCNK5 | potassium two pore domain channel subfamily K member 5 | ENCODES a protein that exhibits voltage-gated potassium channel activity (ortholog); INVOLVED IN potassium ion export across plasma membrane (ortholog); potassium ion import across plasma membrane (ortholog); regulation of resting membrane potential (ortholog); ASSOCIATED WITH status epilepticus (or tholog); FOUND IN membrane (inferred); INTERACTS WITH ammonia | | | | Pig | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155239582 | kcnk5 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18545507 | KCNK5 | potassium two pore domain channel subfamily K member 5 | ENCODES a protein that exhibits voltage-gated potassium channel activity (ortholog); INVOLVED IN potassium ion export across plasma membrane (ortholog); potassium ion import across plasma membrane (ortholog); regulation of resting membrane potential (ortholog); ASSOCIATED WITH status epilepticus (or tholog); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Green Monkey | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626176851 | kcnk5.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 626183778 | kcnk5.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155258724 | kcnk5.S | | | | | | African Clawed Frog | | symbol | gene, null |