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30 records found for search term Insig2
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
631417Insig2insulin induced gene 2ENCODES a protein that exhibits oxysterol binding (ortholog); protein sequestering activity (ortholog); INVOLVED IN response to fatty acid; response to insulin; response to lipid; PARTICIPATES IN sterol regulatory element-binding protein signaling pathway; ASSOCIATED WITH end stage renal disease; Ex133502516035052937Rat243symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
735428INSIG2insulin induced gene 2The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (2118088471118110997Human238symbol , old_gene_name , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
735429Insig2insulin induced gene 2Predicted to enable oxysterol binding activity and protein sequestering activity. Acts upstream of or within several processes, including cholesterol biosynthetic process; ear morphogenesis; and negative regulation of lipid biosynthetic process. Predicted to be part of SREBP-SCAP-Insig complex. Pred1121232082121260391Mouse262symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
9034186Insig2insulin induced gene 2ENCODES a protein that exhibits oxysterol binding (ortholog); protein sequestering activity (ortholog); INVOLVED IN cholesterol biosynthetic process (ortholog); cholesterol metabolic process (ortholog); cranial suture morphogenesis (ortholog); PARTICIPATES IN sterol regulatory element-binding proteiNW_0049554591157158211596069Chinchilla31symbolgene, protein-coding, MODEL [RefSeq]
11966770INSIG2insulin induced gene 2ENCODES a protein that exhibits lipid binding (inferred); oxysterol binding (inferred); protein sequestering activity (inferred); INVOLVED IN cholesterol biosynthetic process (ortholog); cholesterol metabolic process (ortholog); cranial suture morphogenesis (ortholog); PARTICIPATES IN sterol regulat2B50469715068757Bonobo43symbolgene, protein-coding, MODEL [RefSeq]
12102123INSIG2insulin induced gene 2ENCODES a protein that exhibits oxysterol binding (ortholog); protein sequestering activity (ortholog); INVOLVED IN cholesterol biosynthetic process (ortholog); cholesterol metabolic process (ortholog); cranial suture morphogenesis (ortholog); PARTICIPATES IN sterol regulatory element-binding protei193179698431811556Dog38symbolgene, protein-coding, MODEL [RefSeq]
12640653Insig2insulin induced gene 2ENCODES a protein that exhibits lipid binding (inferred); oxysterol binding (inferred); protein sequestering activity (inferred); INVOLVED IN cholesterol biosynthetic process (ortholog); cholesterol metabolic process (ortholog); cranial suture morphogenesis (ortholog); PARTICIPATES IN sterol regulatNW_0049364695212006352140646Squirrel43symbolgene, protein-coding, MODEL [RefSeq]
13845174INSIG2insulin induced gene 2ENCODES a protein that exhibits oxysterol binding (ortholog); INVOLVED IN cholesterol biosynthetic process (ortholog); cholesterol metabolic process (ortholog); cranial suture morphogenesis (ortholog); PARTICIPATES IN sterol regulatory element-binding protein signaling pathway; ASSOCIATED WITH end sPig46symbolgene, protein-coding, PROVISIONAL [RefSeq]
18659067INSIG2insulin induced gene 2ENCODES a protein that exhibits lipid binding (inferred); oxysterol binding (inferred); protein sequestering activity (inferred); INVOLVED IN cholesterol biosynthetic process (ortholog); cholesterol metabolic process (ortholog); cranial suture morphogenesis (ortholog); PARTICIPATES IN sterol regulatGreen Monkey43symbolgene, protein-coding, MODEL [RefSeq]
18916257Insig2insulin induced gene 2ENCODES a protein that exhibits oxysterol binding (ortholog); protein sequestering activity (ortholog); INVOLVED IN cholesterol biosynthetic process (ortholog); cholesterol metabolic process (ortholog); cranial suture morphogenesis (ortholog); PARTICIPATES IN sterol regulatory element-binding proteiNaked Mole-Rat38symbolgene, protein-coding, MODEL [RefSeq]
405860057insig2Tropical Clawed Frogsymbolgene, null
405860194insig2Tropical Clawed Frogsymbolgene, null
405860277insig2Tropical Clawed Frogsymbolgene, null
405860851insig2Tropical Clawed Frogsymbolgene, null
405861310insig2Tropical Clawed Frogsymbolgene, null
405861359insig2Tropical Clawed Frogsymbolgene, null
405862390insig2Tropical Clawed Frogsymbolgene, null
405862480insig2Tropical Clawed Frogsymbolgene, null
405864349insig2Tropical Clawed Frogsymbolgene, null
405865004insig2Tropical Clawed Frogsymbolgene, null
405865270insig2Tropical Clawed Frogsymbolgene, null
405865604insig2Tropical Clawed Frogsymbolgene, null
626105403Insig2insulin induced gene 2ENCODES a protein that exhibits oxysterol binding (ortholog); protein sequestering activity (ortholog); INVOLVED IN cholesterol biosynthetic process (ortholog); cholesterol metabolic process (ortholog); cranial suture morphogenesis (ortholog); PARTICIPATES IN sterol regulatory element-binding proteiBlack Rat31symbolgene, protein-coding, MODEL [RefSeq]
626172910insig2Tropical Clawed Frogsymbolgene, null
626172926insig2Tropical Clawed Frogsymbolgene, null
626181236insig2Tropical Clawed Frogsymbolgene, null
626183812insig2Tropical Clawed Frogsymbolgene, null
626186301insig2Tropical Clawed Frogsymbolgene, null
626188445insig2Tropical Clawed Frogsymbolgene, null
13905178INSIG2Pinsulin induced gene 2 pseudogenePigsymbolgene, pseudo, INFERRED [RefSeq]