| 1345614 | HEPHL1 | hephaestin like 1 | Enables ferroxidase activity. Involved in intracellular iron ion homeostasis. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025] | 11 | 94021354 | 94114208 | Human | 83 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1564835 | Hephl1 | hephaestin-like 1 | ENCODES a protein that exhibits ferroxidase activity (ortholog); INVOLVED IN intracellular iron ion homeostasis (ortholog); ASSOCIATED WITH Lichen Planus Follicularis (ortholog); Pili Torti, Developmental Delay, Neurological Abnormalities (ortholog); FOUND IN membrane (inferred); INTERACTS WITH alph a-Zearalanol; bisphenol A; paracetamol | 8 | 20178190 | 20246698 | Rat | 47 | symbol , old_gene_name , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1622024 | Hephl1 | hephaestin-like 1 | Predicted to enable ferroxidase activity. Predicted to be involved in intracellular iron ion homeostasis. Predicted to act upstream of or within multicellular organismal-level iron ion homeostasis. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in severa l structures, including extraembryonic component; genitourinary system; hippocampal formation; integumental system; and retina. Orthologous to human HEPHL1 (hephaestin like 1). [provided by Alliance of Genome Resources, Jul 2025] | 9 | 14963137 | 15023466 | Mouse | 71 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8748342 | Hephl1 | hephaestin like 1 | ENCODES a protein that exhibits ferroxidase activity (ortholog); INVOLVED IN intracellular iron ion homeostasis (ortholog); ASSOCIATED WITH Lichen Planus Follicularis (ortholog); Pili Torti, Developmental Delay, Neurological Abnormalities (ortholog) | NW_004955414 | 461212 | 551323 | Chinchilla | 5 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11898122 | HEPHL1 | hephaestin like 1 | ENCODES a protein that exhibits copper ion binding (inferred); ferroxidase activity (inferred); metal ion binding (inferred); INVOLVED IN intracellular iron ion homeostasis (inferred); iron ion transport (inferred); monoatomic ion transport (inferred); ASSOCIATED WITH Lichen Planus Follicularis (ort holog); Pili Torti, Developmental Delay, Neurological Abnormalities (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | 11 | 89035265 | 89127508 | Bonobo | 17 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12388437 | HEPHL1 | hephaestin like 1 | ENCODES a protein that exhibits copper ion binding (inferred); ferroxidase activity (inferred); metal ion binding (inferred); INVOLVED IN intracellular iron ion homeostasis (inferred); monoatomic ion transport (inferred); ASSOCIATED WITH Lichen Planus Follicularis (ortholog); Pili Torti, Development al Delay, Neurological Abnormalities (ortholog); FOUND IN membrane (inferred); INTERACTS WITH bisphenol A | 21 | 6720472 | 6813946 | Dog | 15 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12494942 | Hephl1 | hephaestin like 1 | ENCODES a protein that exhibits copper ion binding (inferred); ferroxidase activity (inferred); metal ion binding (inferred); INVOLVED IN intracellular iron ion homeostasis (inferred); iron ion transport (inferred); monoatomic ion transport (inferred); ASSOCIATED WITH Lichen Planus Follicularis (ort holog); Pili Torti, Developmental Delay, Neurological Abnormalities (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | NW_004936674 | 778160 | 846119 | Squirrel | 16 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18411760 | HEPHL1 | hephaestin like 1 | ENCODES a protein that exhibits copper ion binding (inferred); ferroxidase activity (inferred); metal ion binding (inferred); INVOLVED IN intracellular iron ion homeostasis (inferred); iron ion transport (inferred); monoatomic ion transport (inferred); ASSOCIATED WITH Lichen Planus Follicularis (ort holog); Pili Torti, Developmental Delay, Neurological Abnormalities (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Green Monkey | 17 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 625980097 | Hephl1 | hephaestin like 1 | ENCODES a protein that exhibits ferroxidase activity (ortholog); INVOLVED IN intracellular iron ion homeostasis (ortholog); ASSOCIATED WITH Lichen Planus Follicularis (ortholog); Pili Torti, Developmental Delay, Neurological Abnormalities (ortholog) | | | | Black Rat | 5 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18918354 | Hephl1 | hephaestin like 1 | ENCODES a protein that exhibits copper ion binding (inferred); ferroxidase activity (inferred); metal ion binding (inferred); INVOLVED IN intracellular iron ion homeostasis (inferred); iron ion transport (inferred); monoatomic ion transport (inferred); ASSOCIATED WITH Lichen Planus Follicularis (ort holog); Pili Torti, Developmental Delay, Neurological Abnormalities (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Naked Mole-Rat | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155250883 | hephl1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14091759 | HEPHL1 | hephaestin like 1 | ENCODES a protein that exhibits copper ion binding (inferred); ferroxidase activity (inferred); metal ion binding (inferred); INVOLVED IN intracellular iron ion homeostasis (inferred); monoatomic ion transport (inferred); ASSOCIATED WITH Lichen Planus Follicularis (ortholog); Pili Torti, Development al Delay, Neurological Abnormalities (ortholog); FOUND IN membrane (inferred) | | | | Pig | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155245665 | hephl1.L | | | | | | African Clawed Frog | | symbol | gene, null |
