| 1310649 | Grwd1 | glutamate-rich WD repeat containing 1 | ENCODES a protein that exhibits chromatin binding (ortholog); DNA replication origin binding (ortholog); histone binding (ortholog); INVOLVED IN DNA replication (ortholog); nucleosome assembly (ortholog); nucleosome disassembly (ortholog); ASSOCIATED WITH Animal Disease Models (ortholog); congenital diarrhea (ortholog); congenital diarrhea 14 (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; bisphenol A | 1 | 105437708 | 105443410 | Rat | 136 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1321677 | Grwd1 | glutamate-rich WD repeat containing 1 | Predicted to enable DNA replication origin binding activity; chromatin binding activity; and histone binding activity. Predicted to be involved in DNA replication; nucleosome organization; and ribosome biogenesis. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of protein-co ntaining complex. Predicted to be active in nucleolus. Is expressed in embryo. Orthologous to human GRWD1 (glutamate rich WD repeat containing 1). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 45474647 | 45480218 | Mouse | 142 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1344190 | GRWD1 | glutamate rich WD repeat containing 1 | This gene encodes a glutamate-rich protein that contains five WD-repeat motifs. The encoded protein may play a critical role in ribosome biogenesis and may also play a role in histone methylation through interactions with CUL4-DDB1 ubiquitin E3 ligase. [provided by RefSeq, Feb 2012] | 19 | 48445983 | 48457022 | Human | 133 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8924514 | Grwd1 | glutamate rich WD repeat containing 1 | ENCODES a protein that exhibits chromatin binding (ortholog); DNA replication origin binding (ortholog); histone binding (ortholog); INVOLVED IN DNA replication (ortholog); nucleosome assembly (ortholog); nucleosome disassembly (ortholog); ASSOCIATED WITH Animal Disease Models (ortholog); congenital diarrhea (ortholog); congenital diarrhea 14 (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | NW_004955559 | 2033743 | 2039493 | Chinchilla | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11883380 | GRWD1 | glutamate rich WD repeat containing 1 | ENCODES a protein that exhibits chromatin binding (ortholog); DNA replication origin binding (ortholog); histone binding (ortholog); INVOLVED IN nucleosome assembly (ortholog); nucleosome disassembly (ortholog); ASSOCIATED WITH Animal Disease Models (ortholog); congenital diarrhea (ortholog); congen ital diarrhea 14 (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); protein-containing complex (ortholog) | 19 | 45447004 | 45455976 | Bonobo | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12177597 | GRWD1 | glutamate rich WD repeat containing 1 | ENCODES a protein that exhibits chromatin binding (inferred); DNA replication origin binding (inferred); histone binding (inferred); INVOLVED IN DNA replication (inferred); nucleosome assembly (inferred); nucleosome disassembly (inferred); ASSOCIATED WITH Animal Disease Models (ortholog); congenital diarrhea (ortholog); congenital diarrhea 14 (ortholog); FOUND IN chromosome (inferred); nucleolus (inferred); nucleoplasm (inferred) | 1 | 107814402 | 107821107 | Dog | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12574999 | Grwd1 | glutamate rich WD repeat containing 1 | ENCODES a protein that exhibits chromatin binding (inferred); DNA replication origin binding (inferred); histone binding (inferred); INVOLVED IN DNA replication (inferred); nucleosome assembly (inferred); nucleosome disassembly (inferred); ASSOCIATED WITH Animal Disease Models (ortholog); congenital diarrhea (ortholog); congenital diarrhea 14 (ortholog); FOUND IN chromosome (inferred); nucleolus (inferred); nucleoplasm (inferred) | NW_004936664 | 2548178 | 2555234 | Squirrel | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13896186 | GRWD1 | glutamate rich WD repeat containing 1 | ENCODES a protein that exhibits chromatin binding (inferred); DNA replication origin binding (inferred); histone binding (inferred); INVOLVED IN DNA replication (inferred); nucleosome assembly (inferred); nucleosome disassembly (inferred); ASSOCIATED WITH Animal Disease Models (ortholog); congenital diarrhea (ortholog); congenital diarrhea 14 (ortholog); FOUND IN chromosome (inferred); nucleolus (inferred); nucleoplasm (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155239730 | grwd1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625851969 | Grwd1 | glutamate rich WD repeat containing 1 | ENCODES a protein that exhibits chromatin binding (ortholog); DNA replication origin binding (ortholog); histone binding (ortholog); INVOLVED IN DNA replication (ortholog); nucleosome assembly (ortholog); nucleosome disassembly (ortholog); ASSOCIATED WITH Animal Disease Models (ortholog); congenital diarrhea (ortholog); congenital diarrhea 14 (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | | | | Black Rat | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18371328 | GRWD1 | glutamate rich WD repeat containing 1 | ENCODES a protein that exhibits chromatin binding (inferred); DNA replication origin binding (inferred); histone binding (inferred); INVOLVED IN DNA replication (inferred); nucleosome assembly (inferred); nucleosome disassembly (inferred); ASSOCIATED WITH Animal Disease Models (ortholog); congenital diarrhea (ortholog); congenital diarrhea 14 (ortholog); FOUND IN chromosome (inferred); nucleolus (inferred); nucleoplasm (inferred) | | | | Green Monkey | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18920574 | Grwd1 | glutamate rich WD repeat containing 1 | ENCODES a protein that exhibits chromatin binding (ortholog); DNA replication origin binding (ortholog); histone binding (ortholog); INVOLVED IN DNA replication (ortholog); nucleosome assembly (ortholog); nucleosome disassembly (ortholog); ASSOCIATED WITH Animal Disease Models (ortholog); congenital diarrhea (ortholog); congenital diarrhea 14 (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); protein-containing complex (ortholog) | | | | Naked Mole-Rat | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155237295 | grwd1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155236635 | grwd1.S | | | | | | African Clawed Frog | | symbol | gene, null |