Gpx6 Gene Search Result

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13 records found for search term Gpx6

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
628789	Gpx6	glutathione peroxidase 6	ENCODES a protein that exhibits glutathione peroxidase activity (inferred); oxidoreductase activity (inferred); peroxidase activity (inferred); INVOLVED IN cellular oxidant detoxification (inferred); response to oxidative stress (inferred); PARTICIPATES IN arachidonic acid metabolic pathway; glutath ... (more) ione metabolic pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); Huntington's disease (ortholog); ovarian carcinoma (ortholog); FOUND IN extracellular region (inferred); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil	17	48104197	48111816	Rat	70	symbol , PhenoGen	gene, protein-coding, REVIEWED [RefSeq]
733327	Gpx6	glutathione peroxidase 6	This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidases catalyze the reduction of a variety of hydroperoxides using glutathione as a specific electron donor substrate, and thereby protect cells against oxidative damage. Expression of this gene is restricted to embryo ... (more) s and adult olfactory epithelium. The mouse and rat orthologs contain a cysteine (Cys) residue at the active site, unlike the human counterpart, which is a selenoprotein, containing selenocysteine (Sec) instead. [provided by RefSeq, Jul 2017]	13	21479635	21503795	Mouse	70	symbol , PhenoGen	gene, protein-coding, REVIEWED [RefSeq]
735998	GPX6	glutathione peroxidase 6	The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of hydrogen peroxide, organic hydroperoxides and lipid hydroperoxides, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, ... (more) which vary in cellular location and substrate specificity. Expression of this gene has been observed in embryos and olfactory epithelium; however, the exact function of this gene is not known. This isozyme is a selenoprotein in humans, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. The orthologs of this gene in mouse and rat (and some other species) contain a cysteine (Cys) residue in place of the Sec residue, and their corresponding mRNAs lack SECIS element. [provided by RefSeq, Jul 2017]	6	28503296	28515793	Human	69	symbol , old_gene_name , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
11761334	GPX6	glutathione peroxidase 6	ENCODES a protein that exhibits glutathione peroxidase activity (inferred); oxidoreductase activity (inferred); peroxidase activity (inferred); INVOLVED IN cellular oxidant detoxification (inferred); response to oxidative stress (inferred); ASSOCIATED WITH autism spectrum disorder (ortholog); Huntin ... (more) gton's disease (ortholog); ovarian carcinoma (ortholog); FOUND IN extracellular region (inferred)	6	28317217	28330024	Bonobo	12	symbol	gene, protein-coding, MODEL [RefSeq]
12357178	GPX6	glutathione peroxidase 6	ENCODES a protein that exhibits glutathione peroxidase activity (inferred); oxidoreductase activity (inferred); peroxidase activity (inferred); INVOLVED IN cellular oxidant detoxification (inferred); response to oxidative stress (inferred); ASSOCIATED WITH autism spectrum disorder (ortholog); Huntin ... (more) gton's disease (ortholog); ovarian carcinoma (ortholog); FOUND IN extracellular region (inferred)	35	25620843	25630288	Dog	12	symbol	gene, protein-coding, VALIDATED [RefSeq]
12552694	Gpx6	glutathione peroxidase 6	ENCODES a protein that exhibits glutathione peroxidase activity (inferred); oxidoreductase activity (inferred); peroxidase activity (inferred); INVOLVED IN cellular oxidant detoxification (inferred); response to oxidative stress (inferred); ASSOCIATED WITH autism spectrum disorder (ortholog); Huntin ... (more) gton's disease (ortholog); ovarian carcinoma (ortholog); FOUND IN extracellular region (inferred)	NW_004936914	535324	543114	Squirrel	12	symbol	gene, protein-coding, MODEL [RefSeq]
18470559	GPX6	glutathione peroxidase 6	ASSOCIATED WITH autism spectrum disorder (ortholog); Huntington's disease (ortholog); ovarian carcinoma (ortholog)				Green Monkey	3	symbol	gene, protein-coding, MODEL [RefSeq]
626079692	Gpx6	glutathione peroxidase 6	ASSOCIATED WITH autism spectrum disorder (ortholog); Huntington's disease (ortholog); ovarian carcinoma (ortholog)				Black Rat	3	symbol	gene, protein-coding, MODEL [RefSeq]
13864596	GPX6	glutathione peroxidase 6	ENCODES a protein that exhibits glutathione peroxidase activity (inferred); oxidoreductase activity (inferred); peroxidase activity (inferred); INVOLVED IN cellular oxidant detoxification (inferred); response to oxidative stress (inferred); ASSOCIATED WITH autism spectrum disorder (ortholog); Huntin ... (more) gton's disease (ortholog); ovarian carcinoma (ortholog); FOUND IN extracellular region (inferred); INTERACTS WITH ethanol; malathion; zearalenone				Pig	15	symbol	gene, protein-coding, VALIDATED [RefSeq]
1315932	GPX7	glutathione peroxidase 7	Enables catalase activity. Predicted to be involved in cellular response to oxidative stress. Located in endoplasmic reticulum. Implicated in Barrett's adenocarcinoma and Barrett's esophagus. [provided by Alliance of Genome Resources, Jul 2025]	1	52602371	52609051	Human	163	old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]
1315933	Gpx7	glutathione peroxidase 7	Predicted to enable catalase activity. Predicted to be involved in cellular oxidant detoxification and response to oxidative stress. Predicted to be located in endoplasmic reticulum. Is expressed in several structures, including alimentary system; brain; integumental system; nose; and skeleton. Huma ... (more) n ortholog(s) of this gene implicated in Barrett's adenocarcinoma and Barrett's esophagus. Orthologous to human GPX7 (glutathione peroxidase 7). [provided by Alliance of Genome Resources, Apr 2025]	4	108257414	108263910	Mouse	188	old_gene_symbol	gene, protein-coding, PROVISIONAL [RefSeq]
18936718	LOC101698217	glutathione peroxidase 6	ENCODES a protein that exhibits glutathione peroxidase activity (inferred); oxidoreductase activity (inferred); peroxidase activity (inferred); INVOLVED IN cellular oxidant detoxification (inferred); response to oxidative stress (inferred); FOUND IN extracellular region (inferred)				Naked Mole-Rat	9	old_gene_symbol	gene, protein-coding, MODEL [RefSeq]
8938760	LOC102008207	glutathione peroxidase 6		NW_004955465	13770938	13774725	Chinchilla		ensembl_gene_symbol , old_gene_symbol	gene, protein-coding, MODEL [RefSeq]