| 1353149 | GPR171 | G protein-coupled receptor 171 | Predicted to enable G protein-coupled purinergic nucleotide receptor activity; neuropeptide binding activity; and neuropeptide receptor activity. Predicted to be involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway; regulation of feeding behavior; and regulation of s ensory perception of pain. Predicted to act upstream of or within negative regulation of myeloid cell differentiation. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025] | 3 | 151197754 | 151203216 | Human | 78 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1585271 | Gpr171 | G protein-coupled receptor 171 | ENCODES a protein that exhibits G protein-coupled peptide receptor activity (ortholog); neuropeptide binding (ortholog); neuropeptide receptor activity (ortholog); INVOLVED IN G protein-coupled receptor signaling pathway; adenylate cyclase-modulating G protein-coupled receptor signaling pathway (ort holog); negative regulation of myeloid cell differentiation (ortholog); FOUND IN plasma membrane; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 2 | 145510305 | 145515392 | Rat | 84 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1619850 | Gpr171 | G protein-coupled receptor 171 | Enables neuropeptide binding activity and neuropeptide receptor activity. Involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway; regulation of feeding behavior; and regulation of sensory perception of pain. Acts upstream of or within negative regulation of myeloid cel l differentiation. Located in plasma membrane. Orthologous to human GPR171 (G protein-coupled receptor 171). [provided by Alliance of Genome Resources, Jul 2025] | 3 | 59003869 | 59009242 | Mouse | 72 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8773861 | Gpr171 | G protein-coupled receptor 171 | ENCODES a protein that exhibits G protein-coupled peptide receptor activity (ortholog); neuropeptide binding (ortholog); neuropeptide receptor activity (ortholog); INVOLVED IN adenylate cyclase-modulating G protein-coupled receptor signaling pathway (ortholog); G protein-coupled receptor signaling p athway (ortholog); negative regulation of myeloid cell differentiation (ortholog); FOUND IN plasma membrane (ortholog) | NW_004955448 | 2335560 | 2341261 | Chinchilla | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11789299 | GPR171 | G protein-coupled receptor 171 | ENCODES a protein that exhibits G protein-coupled peptide receptor activity (inferred); G protein-coupled purinergic nucleotide receptor activity (inferred); G protein-coupled receptor activity (inferred); INVOLVED IN negative regulation of myeloid cell differentiation (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | 3 | 148226394 | 148231792 | Bonobo | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12078815 | GPR171 | G protein-coupled receptor 171 | ENCODES a protein that exhibits G protein-coupled peptide receptor activity (inferred); G protein-coupled receptor activity (inferred); neuropeptide binding (inferred); INVOLVED IN negative regulation of myeloid cell differentiation (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred ) | 23 | 45782265 | 45784517 | Dog | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12670347 | Gpr171 | G protein-coupled receptor 171 | ENCODES a protein that exhibits G protein-coupled peptide receptor activity (inferred); G protein-coupled purinergic nucleotide receptor activity (inferred); G protein-coupled receptor activity (inferred); INVOLVED IN negative regulation of myeloid cell differentiation (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | NW_004936758 | 1480035 | 1481490 | Squirrel | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14276722 | GPR171 | G protein-coupled receptor 171 | ENCODES a protein that exhibits G protein-coupled peptide receptor activity (inferred); G protein-coupled receptor activity (inferred); neuropeptide binding (inferred); INVOLVED IN negative regulation of myeloid cell differentiation (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred ) | | | | Pig | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18611864 | GPR171 | G protein-coupled receptor 171 | ENCODES a protein that exhibits G protein-coupled peptide receptor activity (inferred); G protein-coupled purinergic nucleotide receptor activity (inferred); G protein-coupled receptor activity (inferred); INVOLVED IN negative regulation of myeloid cell differentiation (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Green Monkey | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18915503 | Gpr171 | G protein-coupled receptor 171 | ENCODES a protein that exhibits G protein-coupled peptide receptor activity (ortholog); neuropeptide binding (ortholog); neuropeptide receptor activity (ortholog); INVOLVED IN adenylate cyclase-modulating G protein-coupled receptor signaling pathway (ortholog); negative regulation of myeloid cell di fferentiation (ortholog); regulation of feeding behavior (ortholog); FOUND IN plasma membrane (ortholog) | | | | Naked Mole-Rat | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 284119962 | gpr171 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625986029 | Gpr171 | G protein-coupled receptor 171 | ENCODES a protein that exhibits G protein-coupled peptide receptor activity (ortholog); neuropeptide binding (ortholog); neuropeptide receptor activity (ortholog); INVOLVED IN adenylate cyclase-modulating G protein-coupled receptor signaling pathway (ortholog); G protein-coupled receptor signaling p athway (ortholog); negative regulation of myeloid cell differentiation (ortholog); FOUND IN plasma membrane (ortholog) | | | | Black Rat | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 288053490 | gpr171.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 284833294 | gpr171.S | | | | | | African Clawed Frog | | symbol | gene, null |